A phase II and pharmacodynamic study of gefitinib in patients with refractory or recurrent epithelial ovarian cancer

Autor: Lori M. Minasian, Virginia Espina, Seth M. Steinberg, Edwin M. Posadas, Elise C. Kohn, Bradford J. Wood, Virginia Kwitkowski, Meghan S. Liel, Andrew K. Godwin, Mahrukh M. Hussain

Publikováno v: Cancer. 109:1323-1330

BACKGROUND The primary objective of this study was to evaluate the biochemical effects of gefitinib on its target signal-transduction pathways in patients with recurrent epithelial ovarian cancer (EOC). The secondary objectives included assessing cli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d81832b0fe1754e4d8aabd1a4569af8
https://doi.org/10.1002/cncr.22545

Phase II Trial of Carboxyamidotriazole in Patients With Relapsed Epithelial Ovarian Cancer

Autor: Lori M. Minasian, Ahalya Premkumar, Gisele Sarosy, Eddie Reed, William D. Figg, Seth M. Steinberg, Vyta Kulpa Oliver, Herbert L. Kotz, Suoping Zhai, Elise C. Kohn, Miranda Raggio, Mahrukh M. Hussain

Publikováno v: Journal of Clinical Oncology. 21:4356-4363

Purpose: Carboxyamidotriazole (CAI) is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel–mediated signaling pathways. It inhibits angiogenesis, tumor growth, invasion, and metastasis. We hypothesized that CAI would

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da69144b90446b6b260bccd51f3fe94d
https://doi.org/10.1200/jco.2003.04.136

Angiogenesis and Metastasis

Autor: Gregory J. Sieczkiewicz, Mahrukh M. Hussain, Elise C. Kohn

Publikováno v: Ovarian Cancer ISBN: 9781475735895

Epithelial ovarian cancer constitutes approximately 85% of all ovarian malignancies. The lack of overt symptoms and good screening strategies precludes early diagnosis and thus greater than 70% of patients present with extensive local disease and per

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f8a2e1e3d7592ce07d074dcc4efc5b8
https://doi.org/10.1007/978-1-4757-3587-1_17

A phase II and pharmacodynamic study of gefitinib in patients with refractory or recurrent epithelial ovarian cancerThis is a US government work and, as such, is in the public domain in the United States of America.

Autor: Edwin M. Posadas, Meghan S. Liel, Virginia Kwitkowski, Lori Minasian, Andrew K. Godwin, Mahrukh M. Hussain, Virginia Espina, Bradford J. Wood, Seth M. Steinberg, Elise C. Kohn

Publikováno v: Cancer (0008543X); Apr2007, Vol. 109 Issue 7, p1323-1330, 8p

A pilot study to assess the utility of a freely downloadable mobile application simulator for undergraduate clinical skills training: a single-blinded, randomised controlled trial.

Autor: Bartlett RD; UCL Medical School, University College London, London, UK. richard.bartlett.11@ucl.ac.uk., Radenkovic D; UCL Medical School, University College London, London, UK., Mitrasinovic S; UCL Medical School, University College London, London, UK., Cole A; UCL Medical School, University College London, London, UK., Pavkovic I; UCL School of Pharmacy, University College London, London, UK., Denn PCP; UCL School of Pharmacy, University College London, London, UK., Hussain M; UCL Medical School, University College London, London, UK., Kogler M; UCL School of Pharmacy, University College London, London, UK., Koutsopodioti N; UCL Medical School, University College London, London, UK., Uddin W; UCL School of Pharmacy, University College London, London, UK., Beckley I; UCL Medical School, University College London, London, UK., Abubakar H; UCL School of Pharmacy, University College London, London, UK., Gill D; UCL Medical School, University College London, London, UK.; Academic Centre for Medical Education, University College London, London, UK., Smith D; Department of Urology, University College London Hospital NHS Foundation Trust, London, UK.

Publikováno v: BMC medical education [BMC Med Educ] 2017 Dec 11; Vol. 17 (1), pp. 247. Date of Electronic Publication: 2017 Dec 11.