Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Mahrukh K Ganapathi"'
Autor:
Susan A.J. Vaziri, Emmanuel J Tavares, Ali R Golshayan, Brian I Rini, Hakan eAydin, Ming eZhou, Linda eSercia, Laura eWood, Mahrukh K Ganapathi, Ronald M Bukowski, Ram eGanapathi
Publikováno v:
Frontiers in Oncology, Vol 2 (2012)
In sporadic clear cell renal cell carcinoma (CCRCC), the von Hippel Lindau (VHL) gene is inactivated by mutation or methylation in the majority of primary (P) tumors. Due to differing effects of wild-type (WT) and mutant (MT) VHL gene on downstream s
Externí odkaz:
https://doaj.org/article/ed11f9d27d1a4e088b609c548e081d2a
Autor:
Ram N. Ganapathi, Nury Steuerwald, Kaitlin E. Klotz, Eric J. Norris, Wendell D. Jones, Mahrukh K. Ganapathi, Jaroslaw P. Maciejewski, Yogin Patel
Publikováno v:
Leukemia & Lymphoma. 62:473-477
All trans retinoic acid (ATRA) has demonstrated curative activity in acute promyelocytic leukemia (APL), a distinct subtype of acute myeloid leukemia (AML), that is characterized by a chromosomal t...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6de4777c2af091aca85327407d830003
https://doi.org/10.1080/10428194.2020.1827245
https://doi.org/10.1080/10428194.2020.1827245
Autor:
David L. Tait, Wendell D. Jones, Chad A. Livasy, Eric J. Norris, Mahrukh K. Ganapathi, Darla Destephanis, Ram N. Ganapathi, Qing Zhang, Ashley P. Sutker
Publikováno v:
The Journal of Pathology
High grade serous ovarian carcinoma (HGSC) without identifiable serous tubal intraepithelial carcinoma (STIC) within the fallopian tube (FT) occurs in approximately 50% of patients. The objective of this study was to use a multisite tumor sampling ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c70569dd536173d710ae0cefdeff96
https://doi.org/10.1002/path.5264
https://doi.org/10.1002/path.5264
Autor:
Eric J, Norris, Yogin C, Patel, Kaitlin E, Klotz, Nury, Steuerwald, Wendell D, Jones, Jaroslaw P, Maciejewski, Ram N, Ganapathi, Mahrukh K, Ganapathi
Publikováno v:
Leukemialymphoma. 62(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18b476e41046d2692a2ec2902ffacc9b
https://pubmed.ncbi.nlm.nih.gov/33064055
https://pubmed.ncbi.nlm.nih.gov/33064055
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Frontiers in Oncology
Aurora A kinase (AAK) involved in G2-M transition is functionally involved in centrosome maturation and maintaining an active spindle assembly checkpoint. We tested the hypothesis that in platinum-taxane resistant high grade serous ovarian cancer (HG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619b66ab797daac173b819496f767d1a
Autor:
Mahrukh K. Ganapathi
Publikováno v:
Acute Phase Proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98bdbd423e2d6604947559f802e9990a
https://doi.org/10.1201/9781003068587-35
https://doi.org/10.1201/9781003068587-35
Autor:
Ram N. Ganapathi, Cheryl L. Willman, Frederick R. Appelbaum, Jerald P. Radich, John E. Godwin, Eric R. Koegle, Shannon McDonough, Megan Othus, Stephen H. Petersdorf, Anjali S. Advani, Mahrukh K. Ganapathi, Andrew P. Michelson, Alan F. List
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Anthracyclines used in the treatment of acute myelogenous leukemia (AML) inhibit the activity of the mammalian topoisomerase II (topo II) isoforms, topo II α and topo IIβ. In 230 patients with non-M3 AML who received frontline ara-C/daunorubicin we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729db0b940d7f3fc374fc55e32a22296
https://doi.org/10.1038/s41598-020-62345-9
https://doi.org/10.1038/s41598-020-62345-9
Autor:
Chad A. Livasy, David L. Tait, Marius Surleac, Issam Hamadeh, Qing Zhang, Andrei J. Petrescu, Eric J. Norris, Mahrukh K. Ganapathi, Darla Destephanis, Jeffrey S. Kneisl, Ram N. Ganapathi, Wendell D. Jones
Publikováno v:
Gynecologic Oncology Reports
Gynecologic Oncology Reports, Vol 23, Iss C, Pp 41-44 (2018)
Gynecologic Oncology Reports, Vol 23, Iss C, Pp 41-44 (2018)
Neurofibromatosis type 1 (NF1) is caused by mutations in the NF1 gene encoding neurofibromin, which negatively regulates Ras signaling. NF1 patients have an increased risk of developing early onset breast cancer, however, the association between NF1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d380e99688888d8861b594d0958771
https://doi.org/10.1016/j.gore.2018.01.005
https://doi.org/10.1016/j.gore.2018.01.005
Autor:
Marius Surleac, Ram N. Ganapathi, Dale Grabowski, Toshiyuki Kozuki, Eric J. Norris, Paul Elson, Andrei J. Petrescu, Kenichi Chikamori, Marius A. Micluta, Mahrukh K. Ganapathi, Andrew C.G. Porter, Gerald A. Hoeltge
Publikováno v:
Nucleic Acids Research
Topoisomerase (topo) IIα and IIβ maintain genome stability and are targets for anti-tumor drugs. In this study, we demonstrate that the decatenation checkpoint is regulated, not only by topo IIα, as previously reported, but also by topo IIβ. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6efccaa7abff0da8ea4b1d98f679e4
https://doi.org/10.1093/nar/gkx325
https://doi.org/10.1093/nar/gkx325
Autor:
Jalid Sehouli, Chad M. Michener, Charles V. Biscotti, Mahrukh K. Ganapathi, Iona Braicu, Ram N. Ganapathi, Wendell D. Jones
Publikováno v:
Cancers
Volume 12
Issue 3
Cancers, Vol 12, Iss 3, p 620 (2020)
Volume 12
Issue 3
Cancers, Vol 12, Iss 3, p 620 (2020)
Immune cell infiltrates within the tumor microenvironment can influence treatment response and outcome in several cancers. In this study, we developed RNA-based immune signatures from pan-cancer analysis that could serve as potential markers across t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30095adf7f94b7aee08de71290dd87ab
https://doi.org/10.3390/cancers12030620
https://doi.org/10.3390/cancers12030620