Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mahrous A. Abou-Salim"'
Autor:
Mater H. Mahnashi, Mohammed Nahari, Hassan Almasoudi, Abdulaziz Alhasaniah, Sara Elgazwi, Mahrous A. Abou-Salim
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
Novel series of nitric oxide-releasing thiazolidine-2,4-diones (NO-TZD-3a-d,5,6) and 3,4,5-trimethoxychalcone-based multifunctional 1,4-dihydropyrimidines (CDHPM-10a-g) have been designed and synthesised as potent broad-spectrum anticancer agents wit
Externí odkaz:
https://doaj.org/article/dc720d31e73c4bbc888d61047edd25b4
Autor:
Mater Mahnashi, Mohammed Merae Alshahrani, Amer Al Ali, Abdulaziz Asiri, Mahrous A. Abou-Salim
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
A novel series of multifunctional pyrazolo[3,4-d]pyrimidine-based glutamate analogs (6a–l and 7a,b) have been designed and synthesized as antifolate anticancer agents. Among the tested compounds, 6i exhibited the most potent anti-proliferative acti
Externí odkaz:
https://doaj.org/article/37b6cde31fe648ccb84d13abb5096226
Autor:
Mahrous A. Abou-Salim, Mohamed A. Shaaban, Mohammed K. Abd El Hameid, Mohammed M. Alanazi, Fathi Halaweish, Yaseen A. M. M. Elshaier
Publikováno v:
Molecules, Vol 28, Iss 6, p 2754 (2023)
A new series of nitric oxide-releasing estra-1,3,5,16-tetraene analogs (NO-∆-16-CIEAs) was designed and synthesized as dual inhibitors for EGFR and MRP2 based on our previous findings on estra-1,3,5-triene analog NO-CIEA 17 against both HepG2 and H
Externí odkaz:
https://doaj.org/article/dc273985dc934dbd84e002d06f76197e
Autor:
Mater H. Mahnashi, Fardous F. El-Senduny, Mohammed Abdulrahman Alshahrani, Mahrous A. Abou-Salim
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 246 (2022)
Over the past few decades, the development of broad-spectrum anticancer agents with anti-angiogenic activity has witnessed considerable progress. In this study, a new series of pyrazolo[3,4-d]pyrimidines based on a phenylfuroxan scaffold were designe
Externí odkaz:
https://doaj.org/article/ccb199febb934fdc8f552c034cc49b83
Autor:
Abdel Haleem M. Hussein, Ahmed A. Khames, Abu-Bakr A. El-Adasy, Ahmed A. Atalla, Mohamed Abdel-Rady, Mohamed I. A. Hassan, Mahrous A. Abou-Salim, Yaseen A. M. M. Elshaier, Assem Barakat
Publikováno v:
Molecules, Vol 26, Iss 4, p 902 (2021)
The elaboration of new small molecules that target phosphodiesterase enzymes (PDEs), especially those of type 5 (PDE5), is an interesting and emerging topic nowadays. A new series of heterocycle-based aminothiazoles were designed and synthesized from
Externí odkaz:
https://doaj.org/article/0762ef94b998490a8d922f4b9b9bf0bf
Publikováno v:
Saudi Pharmaceutical Journal, Vol 24, Iss 2, Pp 119-132 (2016)
In continuation to our previous work, thiazolopyrimidines 2a–x were synthesized through intramolecular cyclization of 2-phenacylthio-dihydropyrimidine hydrobromides 1a–x using polyphosphoric acid. On the other hand, thiazolo[3,2-a]pyrimidine-3-on
Externí odkaz:
https://doaj.org/article/c7df7dcf4f694deb9d41e1d87874d376
Autor:
Mater H. Mahnashi, Yahya S. Alqahtani, Bandar A. Alyami, Ali O. Alqarni, Mohammad Ahmed Alshrahili, Mahrous A. Abou-Salim, Mohammed N. Alqahtani, Sadaf Mushtaq, Abdul Sadiq, Muhammad Saeed Jan
Publikováno v:
Evidence-Based Complementary and Alternative Medicine.
Background. The current study aims to give a scientific origin for employing Habenaria plantaginea Lindl. as a potential candidate against nociception, inflammation, and pyrexia. The pharmacological studies were performed on crude extract and subfrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42855738f1453f0b0480dbe7e9373de9
Autor:
Mater H, Mahnashi, Yahya S, Alqahtani, Bandar A, Alyami, Ali O, Alqarni, Mohammad, Ahmed Alshrahili, Mahrous A, Abou-Salim, Mohammed N, Alqahtani, Sadaf, Mushtaq, Abdul, Sadiq, Muhammad Saeed, Jan
Publikováno v:
Evidence-based complementary and alternative medicine : eCAM. 2022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::86d2649963e00968f361adba1f4f3acb
https://pubmed.ncbi.nlm.nih.gov/35399645
https://pubmed.ncbi.nlm.nih.gov/35399645
Autor:
Mahrous A. Abou-Salim, Abdel Haleem M. Hussein, Yaseen A.M.M. Elshaier, Assem Barakat, Mohamed Abdel-Rady, Abu-Bakr A. A. M. El-Adasy, A. A. Atalla, Mohamed Ibrahim Abu Hassan, Ahmed Khames
Publikováno v:
Molecules, Vol 26, Iss 902, p 902 (2021)
Molecules
Volume 26
Issue 4
Molecules
Volume 26
Issue 4
The elaboration of new small molecules that target phosphodiesterase enzymes (PDEs), especially those of type 5 (PDE5), is an interesting and emerging topic nowadays. A new series of heterocycle-based aminothiazoles were designed and synthesized from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a90e37a5d3d38451c89762f42070762
https://www.mdpi.com/1420-3049/26/4/902
https://www.mdpi.com/1420-3049/26/4/902
Publikováno v:
Saudi Pharmaceutical Journal, Vol 24, Iss 2, Pp 119-132 (2016)
In continuation to our previous work, thiazolopyrimidines 2a-x were synthesized through intramolecular cyclization of 2-phenacylthio-dihydropyrimidine hydrobromides 1a-x using polyphosphoric acid. On the other hand, thiazolo[3,2-a]pyrimidine-3-one 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81aca50102ac50fcd4d37733fc36698c