Suppression of Cisplatin-Induced Hepatic Injury in Rats Through Alarmin High-Mobility Group Box-1 Pathway by Ganoderma lucidum: Theoretical and Experimental Study

Autor: Hassan HM, Al-Wahaibi LH, Elmorsy MA, Mahran YF

Publikováno v: Drug Design, Development and Therapy, Vol Volume 14, Pp 2335-2353 (2020)

Hanan M Hassan,1 Lamya H Al-Wahaibi,2 Mohammed A Elmorsy,3 Yasmen F Mahran4,5 1Department of Pharmacology and Biochemistry, Faculty of Pharmacy, Delta University for Science & Technology, Gamasa City, Dakhliya, Egypt; 2Department of Chemistry, Colleg

Externí odkaz: https://doaj.org/article/818cc54584db43c792db06bccfe2dd9b

Radioprotective Effects of Carvacrol and/or Thymol against Gamma Irradiation-Induced Acute Nephropathy: In Silico and In Vivo Evidence of the Involvement of Insulin-like Growth Factor-1 (IGF-1) and Calcitonin Gene-Related Peptide.

Autor: Mahran YF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt., Al-Kharashi LA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11211, Saudi Arabia., Atawia RT; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.; Department of Pharmaceutical Sciences, College of Pharmacy, Southwestern Oklahoma State University, Weatherford, OK 73096, USA., Alanazi RT; Student, Pharmacy College, King Saud University, Riyadh 11211, Saudi Arabia., Dhahi AMB; Student, Pharmacy College, King Saud University, Riyadh 11211, Saudi Arabia., Alsubaie R; Student, Pharmacy College, King Saud University, Riyadh 11211, Saudi Arabia., Badr AM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11211, Saudi Arabia.

Publikováno v: Biomedicines [Biomedicines] 2023 Sep 13; Vol. 11 (9). Date of Electronic Publication: 2023 Sep 13.

Anti-Alzheimer Activity of Combinations of Cocoa with Vinpocetine or Other Nutraceuticals in Rat Model: Modulation of Wnt3/β-Catenin/GSK-3β/Nrf2/HO-1 and PERK/CHOP/Bcl-2 Pathways.

Autor: Abu-Elfotuh K; Clinical Pharmacy Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11651, Egypt., Tolba AMA; Anatomy Department, Faculty of Medicine, Girls Branch, Al-Azhar University, Cairo 11651, Egypt., Hussein FH; College of Dentistry, University of Alkafeel, Najaf 54001, Iraq., Hamdan AME; Department of Pharmacy Practice, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia., Rabeh MA; Department of Pharmacognosy, College of Pharmacy, King Khalid University, Abha 62521, Saudi Arabia., Alshahri SA; Department of Pharmacognosy, College of Pharmacy, King Khalid University, Abha 62521, Saudi Arabia., Ali AA; Pharmacology and Toxicology Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11651, Egypt., Mosaad SM; Research Unit, Egypt Healthcare Authority, Ismailia Branch, Ismailia 41522, Egypt., Mahmoud NA; Physiology Department, Faculty of Medicine (Girls), Al-Azhar University, Cairo 11651, Egypt., Elsaeed MY; Physiology Department, Faculty of Medicine (Boys), Al-Azhar University, Demietta 34517, Egypt., Abdelglil RM; Department of Anatomy and Embryology, Faculty of Medicine (Girls), Al-Azhar University, Cairo 11651, Egypt., El-Awady RR; Biochemistry and Molecular Biology Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11651, Egypt., Galal ERM; Biochemistry and Molecular Biology Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11651, Egypt., Kamal MM; Pharmacology and Toxicology Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11651, Egypt., Elsisi AMM; Biochemistry and Molecular Biology Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11651, Egypt.; Biochemistry Department, Faculty of Pharmacy, Nahda University (NUB), Beni-Suef 62521, Egypt., Darwish A; Biochemistry Department, Faculty of Pharmacy, Sohag University, Sohag 82524, Egypt., Gowifel AMH; Pharmacology and Toxicology Department, Faculty of Pharmacy, Modern University for Technology and Information (MTI), Cairo 11571, Egypt., Mahran YF; Pharmacology & Toxicology Department, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.

Publikováno v: Pharmaceutics [Pharmaceutics] 2023 Jul 31; Vol. 15 (8). Date of Electronic Publication: 2023 Jul 31.

TLR4/Inflammasomes Cross-Talk and Pyroptosis Contribute to N-Acetyl Cysteine and Chlorogenic Acid Protection against Cisplatin-Induced Nephrotoxicity.

Autor: Badr AM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11211, Saudi Arabia.; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt., Al-Kharashi LA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11211, Saudi Arabia., Attia H; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11211, Saudi Arabia.; Department of Biochemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt., Alshehri S; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11211, Saudi Arabia., Alajami HN; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11211, Saudi Arabia., Ali RA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11211, Saudi Arabia., Mahran YF; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2023 Feb 22; Vol. 16 (3). Date of Electronic Publication: 2023 Feb 22.

The protective effect of thymoquinone or/and thymol against monosodium glutamate-induced attention-deficit/hyperactivity disorder (ADHD)-like behavior in rats: Modulation of Nrf2/HO-1, TLR4/NF-κB/NLRP3/caspase-1 and Wnt/β-Catenin signaling pathways in rat model.

Autor: Abu-Elfotuh K; Pharmacology and Toxicology Department, Faculty of Pharmacy, Al-Azhar University, Cairo 11651, Egypt., Abdel-Sattar SA; Pharmacology and Toxicology Department, Faculty of Pharmacy, Al-Azhar University, Cairo 11651, Egypt., Abbas AN; University of Sulaimanyia, College of Dentistry, Kurdistan, Iraq., Mahran YF; Pharmacology and Toxicology Department, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt., Alshanwani AR; Physiology Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Hamdan AME; Department of Pharmacy Practice, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia. Electronic address: a_hamdan@ut.edu.sa., Atwa AM; Pharmacology and Toxicology Department, Faculty of Pharmacy, Egyptian Russian University, Cairo, Egypt., Reda E; Pharmacology and Toxicology Department, Faculty of Pharmacy, Sinai University, East Kantara Branch, New City, El Ismailia 41611, Egypt., Ahmed YM; Pharmacology and Toxicology Department, Faculty of Pharmacy, Nahda University, Beni-Suef, Egypt., Zaghlool SS; Pharmacology and Toxicology Department, Faculty of Pharmacy, Modern University for Technology and Information (MTI), Mokattam, Cairo 11571, Egypt., El-Din MN; Pharmacology and Toxicology Department, Faculty of Pharmacy, University of Sadat City (USC), Menoufia, Egypt.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Nov; Vol. 155, pp. 113799. Date of Electronic Publication: 2022 Oct 06.