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pro vyhledávání: '"Mahood, RA"'
ESI-IMS-MS: A method for rapid analysis of protein aggregation and its inhibition by small molecules
Electrospray ionisation-ion mobility spectrometry-mass spectrometry (ESI-IMS-MS) is a powerful method for the study of conformational changes in protein complexes, including oligomeric species populated during protein self-aggregation into amyloid fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::54e48a8d6a40ffe06868864a0e4be098
https://eprints.whiterose.ac.uk/91940/8/RadfordESI-IMS-MSamethodforrapidanalysis.pdf
https://eprints.whiterose.ac.uk/91940/8/RadfordESI-IMS-MSamethodforrapidanalysis.pdf
Autor:
Mahood, Rachel Alexandra
Amyloidoses are a group of protein misfolding disorders which are characterised by the abnormal accumulation of highly ordered filamentous assemblies, known as amyloid fibrils. More than 50 human disease states are attributed to this phenomenon, many
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.675531
Autor:
Young LM; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom; School of Molecular and Cellular Biology, University of Leeds, LS2 9JT, United Kingdom. Electronic address: bs08lw@leeds.ac.uk., Saunders JC; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom; School of Molecular and Cellular Biology, University of Leeds, LS2 9JT, United Kingdom. Electronic address: bsjct@leeds.ac.uk., Mahood RA; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom; School of Molecular and Cellular Biology, University of Leeds, LS2 9JT, United Kingdom. Electronic address: bs08ram@leeds.ac.uk., Revill CH; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom; School of Chemistry, University of Leeds, LS2 9JT, United Kingdom. Electronic address: C.H.Revill@leeds.ac.uk., Foster RJ; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom; School of Chemistry, University of Leeds, LS2 9JT, United Kingdom. Electronic address: R.Foster@leeds.ac.uk., Ashcroft AE; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom; School of Molecular and Cellular Biology, University of Leeds, LS2 9JT, United Kingdom. Electronic address: A.E.Ashcroft@leeds.ac.uk., Radford SE; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom; School of Molecular and Cellular Biology, University of Leeds, LS2 9JT, United Kingdom. Electronic address: S.E.Radford@leeds.ac.uk.
Publikováno v:
Methods (San Diego, Calif.) [Methods] 2016 Feb 15; Vol. 95, pp. 62-9. Date of Electronic Publication: 2015 May 22.
Autor:
Saunders JC; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK.; School of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK., Young LM; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK.; School of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK., Mahood RA; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK.; School of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK., Jackson MP; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK.; School of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK., Revill CH; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK.; School of Chemistry, University of Leeds, LS2 9JT, UK., Foster RJ; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK.; School of Chemistry, University of Leeds, LS2 9JT, UK., Smith DA; Avacta Analytical plc, Wetherby, LS23 7FZ, UK., Ashcroft AE; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK.; School of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK., Brockwell DJ; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK.; School of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK., Radford SE; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK.; School of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK.
Publikováno v:
Nature chemical biology [Nat Chem Biol] 2016 Feb; Vol. 12 (2), pp. 94-101. Date of Electronic Publication: 2015 Dec 14.
Autor:
Young LM; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, University of Leeds, LS2 9JT, UK. s.e.radford@leeds.ac.uk a.e.ashcroft@leeds.ac.uk., Mahood RA, Saunders JC, Tu LH, Raleigh DP, Radford SE, Ashcroft AE
Publikováno v:
The Analyst [Analyst] 2015 Oct 21; Vol. 140 (20), pp. 6990-9.
Autor:
Young LM; Astbury Centre for Structural Molecular Biology, University of Leeds, LS2 9JT, UK.; School of Molecular and Cellular Biology, University of Leeds, LS2 9JT, UK., Saunders JC; Astbury Centre for Structural Molecular Biology, University of Leeds, LS2 9JT, UK.; School of Molecular and Cellular Biology, University of Leeds, LS2 9JT, UK., Mahood RA; Astbury Centre for Structural Molecular Biology, University of Leeds, LS2 9JT, UK.; School of Molecular and Cellular Biology, University of Leeds, LS2 9JT, UK., Revill CH; Astbury Centre for Structural Molecular Biology, University of Leeds, LS2 9JT, UK.; School of Chemistry, University of Leeds, LS2 9JT, UK., Foster RJ; Astbury Centre for Structural Molecular Biology, University of Leeds, LS2 9JT, UK.; School of Chemistry, University of Leeds, LS2 9JT, UK., Tu LH; Department of Chemistry, Stony Brook University, Stony Brook, NY 11794-3400, USA., Raleigh DP; Department of Chemistry, Stony Brook University, Stony Brook, NY 11794-3400, USA., Radford SE; Astbury Centre for Structural Molecular Biology, University of Leeds, LS2 9JT, UK.; School of Molecular and Cellular Biology, University of Leeds, LS2 9JT, UK., Ashcroft AE; Astbury Centre for Structural Molecular Biology, University of Leeds, LS2 9JT, UK.; School of Molecular and Cellular Biology, University of Leeds, LS2 9JT, UK.
Publikováno v:
Nature chemistry [Nat Chem] 2015 Jan; Vol. 7 (1), pp. 73-81. Date of Electronic Publication: 2014 Dec 08.