Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mahon L, Maguire"'
Autor:
Mahon L. Maguire, Debra J. McAndrew, Hannah A. Lake, Philip J. Ostrowski, Sevasti Zervou, Stefan Neubauer, Craig A. Lygate, Jurgen E. Schneider
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 25, Iss 1, Pp 1-10 (2023)
Abstract Background Phosphorus cardiovascular magnetic resonance spectroscopy (31P-CMRS) has emerged as an important tool for the preclinical assessment of myocardial energetics in vivo. However, the high rate and diminutive size of the mouse heart i
Externí odkaz:
https://doaj.org/article/2f14a28b965446bc9091be7fea4b46e5
Autor:
Arash Yavari, Mohamed Bellahcene, Annalisa Bucchi, Syevda Sirenko, Katalin Pinter, Neil Herring, Julia J. Jung, Kirill V. Tarasov, Emily J. Sharpe, Markus Wolfien, Gabor Czibik, Violetta Steeples, Sahar Ghaffari, Chinh Nguyen, Alexander Stockenhuber, Joshua R. St. Clair, Christian Rimmbach, Yosuke Okamoto, Dongmei Yang, Mingyi Wang, Bruce D. Ziman, Jack M. Moen, Daniel R. Riordon, Christopher Ramirez, Manuel Paina, Joonho Lee, Jing Zhang, Ismayil Ahmet, Michael G. Matt, Yelena S. Tarasova, Dilair Baban, Natasha Sahgal, Helen Lockstone, Rathi Puliyadi, Joseph de Bono, Owen M. Siggs, John Gomes, Hannah Muskett, Mahon L. Maguire, Youlia Beglov, Matthew Kelly, Pedro P. N. dos Santos, Nicola J. Bright, Angela Woods, Katja Gehmlich, Henrik Isackson, Gillian Douglas, David J. P. Ferguson, Jürgen E. Schneider, Andrew Tinker, Olaf Wolkenhauer, Keith M. Channon, Richard J. Cornall, Eduardo B. Sternick, David J. Paterson, Charles S. Redwood, David Carling, Catherine Proenza, Robert David, Mirko Baruscotti, Dario DiFrancesco, Edward G. Lakatta, Hugh Watkins, Houman Ashrafian
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
AMPK regulates cellular energy balance using its γ subunit as an energy sensor of cellular AMP and ADP to ATP ratios. Here, the authors show that γ2 AMPK activation lowers heart rate by reducing the activity of pacemaker cells, whereas loss of γ2
Externí odkaz:
https://doaj.org/article/93dc1bb6f94248b0bbd5f23512479816
Autor:
Jana Koth, Mahon L. Maguire, Darryl McClymont, Leonie Diffley, Victoria L. Thornton, John Beech, Roger K. Patient, Paul R. Riley, Jürgen E. Schneider
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The adult zebrafish is a well-established model for studying heart regeneration, but due to its tissue opaqueness, repair has been primarily assessed using destructive histology, precluding repeated investigations of the same animal. We pres
Externí odkaz:
https://doaj.org/article/df3a001c45664798981cda1674ac34b4
Autor:
Stephen Faulkner, Jürgen E. Schneider, Mahon L. Maguire, Kezi Yao, Louise R. Tear, Manuel Tropiano, Nicola J. Farrer
Publikováno v:
Dalton Trans
The kinetically stable heptadentate gadolinium complex Gd.pDO3A (1.Gd) demonstrates significant31P nuclear magnetic resonance (NMR) relaxation enhancement of biologically relevant phosphate species; adenosine triphosphate (ATP), phosphocreatine (PCr)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483d51e98fa02e2b1a58d0ca3eba2305
https://europepmc.org/articles/PMC7610995/
https://europepmc.org/articles/PMC7610995/
Autor:
Jürgen E. Schneider, Sevasti Zervou, Hannah A Lake, Mahon L. Maguire, Stefan Neubauer, Debra J. McAndrew, Craig A. Lygate, Fang Cao
Publikováno v:
Basic Research in Cardiology
Mitochondrial creatine kinase (Mt-CK) is a major determinant of cardiac energetic status and is down-regulated in chronic heart failure, which may contribute to disease progression. We hypothesised that cardiomyocyte-specific overexpression of Mt-CK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba23fde81e23071c4f6e8828db8518dc
https://eprints.whiterose.ac.uk/155800/1/Cao2020_Article_OverexpressionOfMitochondrialC.pdf
https://eprints.whiterose.ac.uk/155800/1/Cao2020_Article_OverexpressionOfMitochondrialC.pdf
Autor:
Mala, Gunadasa-Rohling, Megan, Masters, Mahon L, Maguire, Sean C, Smart, Jürgen E, Schneider, Paul R, Riley
Publikováno v:
Circulation. 138(21)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99f0ca9ac4629262676ba5406c4832a1
https://pubmed.ncbi.nlm.nih.gov/30779647
https://pubmed.ncbi.nlm.nih.gov/30779647
Autor:
Mala Gunadasa-Rohling, Jürgen E. Schneider, Sean Smart, Paul R. Riley, Mahon L. Maguire, Megan Masters
We present longitudinal magnetic resonance imaging (MRI) of neonatal mouse hearts during the first three weeks following coronary artery ligation to mimic heart attack. We confirm heart regeneration in individual animals injured on post-natal day 1 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64ef46fc81f32b8353ebb2ea21d79aa
https://doi.org/10.1101/329474
https://doi.org/10.1101/329474
Autor:
Eileen McNeill, Ricardo Carnicer, Carolyn A. Carr, Christakis Constantinides, Mangala Srinivas, Mahon L. Maguire, Jürgen E. Schneider, Edyta Swider
Publikováno v:
PLoS ONE
PLOS ONE
PLoS One, 13, 1
PLoS One, 13
PLoS ONE, Vol 13, Iss 1, p e0190558 (2018)
PLOS ONE
PLoS One, 13, 1
PLoS One, 13
PLoS ONE, Vol 13, Iss 1, p e0190558 (2018)
PurposeTo a) achieve cardiac 19F-Magnetic Resonance Imaging (MRI) of perfluoro-crown-ether (PFCE) labeled cardiac progenitor stem cells (CPCs) and bone-derived bone marrow macrophages, b) determine label concentration and cellular load limits, and c)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00b2b7b4d998f092a10175e5bebc29a
https://doi.org/10.1371/journal.pone.0190558
https://doi.org/10.1371/journal.pone.0190558
Autor:
Mahon L. Maguire
Publikováno v:
Protocols and Methodologies in Basic Science and Clinical Cardiac MRI ISBN: 9783319530000
Heart disease, and specifically heart failure, result from a complex interaction of genetics, metabolism, and physical insult/ischaemia that lead to changes in myocardial metabolism, gene expression, hypertrophy, cell death, or scarring. Magnetic res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86ea97941e22d7df681ac93df4a4a0f7
https://doi.org/10.1007/978-3-319-53001-7_5
https://doi.org/10.1007/978-3-319-53001-7_5
Autor:
Claus Svendsen, David J. Spurgeon, Steven Lofts, Mahon L. Maguire, Stephanie Sdepanian, Julian L. Griffin, Oliver A.H. Jones
Publikováno v:
Environmental Toxicology and Chemistry. 33:61-64
Metabolic profiling can be used to assess the changes in biochemical profiles of soil communities living in contaminated sites. The term “community metabolomics” is proposed for the application of metabolomics techniques to the study of the entir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf28b6a52172a94a8d8505b433bdbc2a
https://doi.org/10.1002/etc.2418
https://doi.org/10.1002/etc.2418