Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Mahomi Kuroiwa"'
Autor:
Hideo Hagihara, Hirotaka Shoji, Mahomi Kuroiwa, Isabella A. Graef, Gerald R. Crabtree, Akinori Nishi, Tsuyoshi Miyakawa
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-15 (2022)
Abstract Calcineurin (Cn), a phosphatase important for synaptic plasticity and neuronal development, has been implicated in the etiology and pathophysiology of neuropsychiatric disorders, including schizophrenia, intellectual disability, autism spect
Externí odkaz:
https://doaj.org/article/aeec4a2f46d940b491afbe3c0d41d828
Autor:
Tetsushi Niiyama, Mahomi Kuroiwa, Yusaku Yoshioka, Yosuke Kitahara, Takahide Shuto, Tatsuyuki Kakuma, Keisuke Ohta, Kei-ichiro Nakamura, Akinori Nishi, Mami Noda
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Thyroid hormones are critical for the regulation of development and differentiation of neurons and glial cells in the central nervous system (CNS). We have previously reported the sex-dependent changes of glial morphology in the brain under the state
Externí odkaz:
https://doaj.org/article/bcdb8003fa7d47fa85965380121b400b
Autor:
Yosuke Kitahara, Keisuke Ohta, Hiroshi Hasuo, Takahide Shuto, Mahomi Kuroiwa, Naoki Sotogaku, Akinobu Togo, Kei-ichiro Nakamura, Akinori Nishi
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147307 (2016)
A selective serotonin reuptake inhibitor is the most commonly prescribed antidepressant for the treatment of major depression. However, the mechanisms underlying the actions of selective serotonin reuptake inhibitors are not fully understood. In the
Externí odkaz:
https://doaj.org/article/f554dde0148746218c8c43969d9918c9
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 53:275-279
Autor:
Katsunori, Kobayashi, Kisako, Shikano, Mahomi, Kuroiwa, Mio, Horikawa, Wakana, Ito, Akinori, Nishi, Eri, Segi-Nishida, Hidenori, Suzuki
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(33)
Dopamine D
Autor:
Mahomi Kuroiwa, Akinori Nishi, Yukie Kawahara, Yoshinori N. Ohnishi, Takaichi Fukuda, Takahide Shuto, Keita Sugiyama, Yuta Miyamoto
Publikováno v:
J Neurosci
The Journal of neuroscience 41(30):6388-6414, 2021
The Journal of neuroscience 41(30):6388-6414, 2021
The striatum is the main structure of the basal ganglia. The striatum receives inputs from various cortical areas, and its subregions play distinct roles in motor and emotional functions. Recently, striatal maps based on corticostriatal connectivity
Autor:
Katsunori Kobayashi, Kisako Shikano, Mahomi Kuroiwa, Mio Horikawa, Wakana Ito, Akinori Nishi, Eri Segi-Nishida, Hidenori Suzuki
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Dopamine D 1 receptors (D 1 Rs) in the hippocampal dentate gyrus (DG) are essential for antidepressant effects. However, the midbrain dopaminergic neurons, the major source of dopamine in the brain, only sparsely project to DG, suggesting possible ac
Autor:
Mahomi Kuroiwa, Takahide Shuto, Taku Nagai, Mutsuki Amano, Kozo Kaibuchi, Angus C. Nairn, Akinori Nishi
Publikováno v:
Neurochemistry international. 162
Dopamine regulates psychomotor function by D1 receptor/PKA-dependent phosphorylation of DARPP-32. DARPP-32, phosphorylated at Thr34 by PKA, inhibits protein phosphatase 1 (PP1), and amplifies the phosphorylation of other PKA/PP1 substrates following
Autor:
Minae Niwa, Tom Macpherson, Takatoshi Hikida, Akinori Nishi, Naoki Sotogaku, Makiko Morita, Takahide Shuto, Mahomi Kuroiwa, Akira Sawa
Publikováno v:
Neurosci Res
Development of drug addictive behaviors is modulated by both genetic and environmental risk factors. However, the molecular mechanisms remain unknown. To address the role of adolescent stress in the development of drug addiction, we combined a transg
Autor:
Yong-Seok Oh, Paul Greengard, Takahide Shuto, Yong Kim, Tsuyoshi Miyakawa, Akinori Nishi, Jin Hyeok Jang, Mahomi Kuroiwa, Chang Hoon Shin, Yukie Kawahara, Yuuki Hanada, Yoshinori N. Ohnishi, Naoki Sotogaku
Publikováno v:
Molecular Psychiatry
Depression is a leading cause of disability. Current pharmacological treatment of depression is insufficient, and development of improved treatments especially for treatment-resistant depression is desired. Understanding the neurobiology of antidepre