Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Maho Sugawa"'
Autor:
Hsu-Wen Chao, Masao Doi, Jean-Michel Fustin, Huatao Chen, Kimihiko Murase, Yuki Maeda, Hida Hayashi, Rina Tanaka, Maho Sugawa, Naoki Mizukuchi, Yoshiaki Yamaguchi, Jun-ichirou Yasunaga, Masao Matsuoka, Mashito Sakai, Michihiro Matsumoto, Shinshichi Hamada, Hitoshi Okamura
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Circadian clock regulates hepatic gene expression and functions. Here Chao et al. show that alteration of circadian clock genes by Period deletion induces polyploidy in hepatocytes due to impaired regulation of Erk signaling by mitogen-activated prot
Externí odkaz:
https://doaj.org/article/00c4c91b8a014bdc961074b75b4bbb0b
Autor:
Kojiro Tsujihana, Kosuke Tanegashima, Yasuko Santo, Hiroyuki Yamada, Sota Akazawa, Ryuta Nakao, Keiko Tominaga, Risa Saito, Yasumasa Nishito, Ryu-Ichiro Hata, Tomonori Nakamura, Iori Murai, Yuka Kono, Maho Sugawa, Miki Tanioka, Gyohei Egawa, Masao Doi, Tadashi Isa, Kenji Kabashima, Takahiko Hara, Hitoshi Okamura
Publikováno v:
Proceedings of the National Academy of Sciences (PNAS). 119(25)
The epidermis is the outermost layer of the skin and the body’s primary barrier to external pathogens; however, the early epidermal immune response remains to be mechanistically understood. We show that the chemokine CXCL14, produced by epidermal k
Publikováno v:
The Journal of Cell Biology
The IFT-B complex powered by kinesin-II is believed to be responsible for anterograde ciliary protein trafficking. Funabashi et al. identify composite interactions of the kinesin-II heterotrimer KIF3A–KIF3B–KAP3 with the IFT-B–connecting tetram
Autor:
Tomoaki Hirano, Mariko Takahara, Yuta Tsurumi, Kentaro Nakamura, Maho Sugawa, Yohei Katoh, Kazuhisa Nakayama
Publikováno v:
Human Molecular Genetics. 27:516-528
The intraflagellar transport (IFT) machinery containing the IFT-A and IFT-B complexes mediates ciliary protein trafficking. Mutations in the genes encoding the six subunits of the IFT-A complex (IFT43, IFT121, IFT122, IFT139, IFT140, and IFT144) are
Autor:
Michihiro Matsumoto, Maho Sugawa, Hitoshi Okamura, Jun-ichirou Yasunaga, Hida Hayashi, Huatao Chen, Rina Tanaka, Shinshichi Hamada, Jean-Michel Fustin, Naoki Mizukuchi, Yoshiaki Yamaguchi, Yuki Maeda, Masao Doi, Hsu Wen Chao, Masao Matsuoka, Mashito Sakai, Kimihiko Murase
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Chao, HW, Doi, M, Fustin, JM, Chen, H, Murase, K, Maeda, Y, Hayashi, H, Tanaka, R, Sugawa, M, Mizukuchi, N, Yamaguchi, Y, Yasunaga, JI, Matsuoka, M, Sakai, M & Okamura, H 2017, ' Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway. ', Nature Communications . https://doi.org/10.1038/s41467-017-02207-7
Nature Communications
Chao, HW, Doi, M, Fustin, JM, Chen, H, Murase, K, Maeda, Y, Hayashi, H, Tanaka, R, Sugawa, M, Mizukuchi, N, Yamaguchi, Y, Yasunaga, JI, Matsuoka, M, Sakai, M & Okamura, H 2017, ' Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway. ', Nature Communications . https://doi.org/10.1038/s41467-017-02207-7
Nature Communications
Liver metabolism undergoes robust circadian oscillations in gene expression and enzymatic activity essential for liver homeostasis, but whether the circadian clock controls homeostatic self-renewal of hepatocytes is unknown. Here we show that hepatoc
Publikováno v:
Molecular Biology of the Cell
The ciliary kinesin KIF17 is a cargo, but not a motor, of the IFT-B complex. The ciliary entry of KIF17 through the transition zone depends on its binding to IFT-B, as well as on its nuclear localization signal.
Cilia function as cellular antenn
Cilia function as cellular antenn
Autor:
Mariko Takahara, Yohei Katoh, Kentaro Nakamura, Tomoaki Hirano, Maho Sugawa, Yuta Tsurumi, Kazuhisa Nakayama
Publikováno v:
Human Molecular Genetics; Feb2018, Vol. 27 Issue 3, p516-528, 13p
Autor:
Teruki Funabashi1, Yohei Katoh1, Misato Okazaki1, Maho Sugawa1, Kazuhisa Nakayama1 kazunaka@pharm.kyoto-u.ac.jp
Publikováno v:
Journal of Cell Biology. Aug2018, Vol. 217 Issue 8, p2867-2876. 10p.