Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Maho Kawaguchi"'
Autor:
Sayuri Nakamae, Satoshi Miyagawa, Koki Ogawa, Mariko Kamiya, Mayumi Taniguchi, Akari Ono, Maho Kawaguchi, Awet Alem Teklemichael, Jiun-Yu Jian, Tamasa Araki, Yukimi Katagami, Hidefumi Mukai, Takeshi Annoura, Katsuyuki Yui, Kenji Hirayama, Shigeru Kawakami, Shusaku Mizukami
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Recent studies have suggested that CD8+ liver-resident memory T (TRM) cells are crucial in the protection against liver-stage malaria. We used liver-directed mRNA-containing lipid nanoparticles (mRNA-LNPs) to induce liver TRM cells in a murine model.
Externí odkaz:
https://doaj.org/article/1b09044e3da34316bfd14951a1d5b2ae
Autor:
Mariko Kamiya, Makoto Matsumoto, Kazuma Yamashita, Tatsunori Izumi, Maho Kawaguchi, Shusaku Mizukami, Masako Tsurumaru, Hidefumi Mukai, Shigeru Kawakami
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2357 (2022)
Lipid nanoparticles (LNPs) are currently in the spotlight as delivery systems for mRNA therapeutics and have been used in the Pfizer/BioNTech and Moderna COVID-19 vaccines. mRNA-LNP formulations have been indicated to require strict control, includin
Externí odkaz:
https://doaj.org/article/73cb2ce7ea2341fb9ed3d64b9cb8da05
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1810 (2021)
Renal dysfunction is often associated with the inflammatory cascade, leading to non-reversible nephrofibrosis. Gene therapy has the ability to treat the pathology. However, the difficulty in introducing genes into the kidney, via either viral vectors
Externí odkaz:
https://doaj.org/article/fcae87e9a1ee4988aeb9d5cb3859540f
Autor:
Koyo Nishimura, Koki Ogawa, Maho Kawaguchi, Shintaro Fumoto, Hidefumi Mukai, Shigeru Kawakami
Publikováno v:
Pharmaceutics, Vol 13, Iss 1, p 115 (2021)
Gene therapy is expected to be used for the treatment of peritoneal fibrosis, which is a serious problem associated with long-term peritoneal dialysis. Hepatocyte growth factor (HGF) is a well-known anti-fibrotic gene. We developed an ultrasound and
Externí odkaz:
https://doaj.org/article/3bf888a3d7e8454289d82a4813d57a45
Autor:
Natsuko Oyama, Haruyuki Takahashi, Maho Kawaguchi, Hirotaka Miyamoto, Koyo Nishida, Masako Tsurumaru, Mikiro Nakashima, Fumiyoshi Yamashita, Mitsuru Hashida, Shigeru Kawakami
Publikováno v:
Pharmaceutics, Vol 12, Iss 2, p 114 (2020)
We previously developed a renal pressure-mediated transfection method (renal pressure method) as a kidney-specific in vivo gene delivery system. However, additional information on selecting other injection routes and applicable animals remains unclea
Externí odkaz:
https://doaj.org/article/14814f4740264229b0f5f48ade01da6a
Publikováno v:
Drug Delivery System. 37:253-262
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50e2724b1f8b6db83ed17f241cf2fac6
https://doi.org/10.2745/dds.37.253
https://doi.org/10.2745/dds.37.253
Autor:
Maho Kawaguchi, Marin Noda, Akari Ono, Mariko Kamiya, Makoto Matsumoto, Masako Tsurumaru, Shusaku Mizukami, Hidefumi Mukai, Shigeru Kawakami
Publikováno v:
Journal of pharmaceutical sciences.
Delivery of messenger RNA (mRNA) by using lipid nanoparticles (LNPs) is expected to be applied to various diseases after the successful clinical use of the mRNA COVID-19 vaccines. This study aimed to evaluate the effect of the cholesterol molar perce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb260b5fd473515eaf20d87756f12365
https://pubmed.ncbi.nlm.nih.gov/36596392
https://pubmed.ncbi.nlm.nih.gov/36596392
Autor:
Shintaro Fumoto, Hidefumi Mukai, Maho Kawaguchi, Shigeru Kawakami, Koyo Nishimura, Koki Ogawa
Publikováno v:
Pharmaceutics
Volume 13
Issue 1
Pharmaceutics, Vol 13, Iss 115, p 115 (2021)
Volume 13
Issue 1
Pharmaceutics, Vol 13, Iss 115, p 115 (2021)
Gene therapy is expected to be used for the treatment of peritoneal fibrosis, which is a serious problem associated with long-term peritoneal dialysis. Hepatocyte growth factor (HGF) is a well-known anti-fibrotic gene. We developed an ultrasound and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80f444b406ab3b63ea2ae5500f43492
http://europepmc.org/articles/PMC7829751
http://europepmc.org/articles/PMC7829751
Autor:
Chizuko Yukizaki, Hiroyuki Sakakibara, Emi Murayama, Masanobu Sakono, Yasushi Matsuura, Daigo Yokoyama, Maho Kawaguchi, Hisato Kunitake
Publikováno v:
Functional Foods in Health and Disease, Vol 8, Iss 9, Pp 447-461 (2018)
Background: Blueberry stems, a by-product of blueberry leaf tea production, are typically discarded. We evaluated the effects of hot-water extracts of rabbiteye blueberry ( Vaccinium virgatum Aiton; RB species) leaves and stems on hepatic lipid level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecfd846dc02f4a68fbb3dc82b2c1b0a1
https://ffhdj.com/index.php/ffhd/article/view/538/861
https://ffhdj.com/index.php/ffhd/article/view/538/861
Autor:
Eiji Kinoshita, Tohru Koike, Elena Tianfei Yuan, Hisashi Hirano, Maho Kawaguchi, Yayoi Kimura, Emiko Kinoshita-Kikuta, Yoko Ino
Publikováno v:
ELECTROPHORESIS. 38:2447-2455
Phosphorylated peptides are attractive targets in the study of the phosphoproteome. Here, we introduce a simple and convenient micropipette-tip method for the separation of phosphorylated and nonphosphorylated peptides by using a phosphate-binding zi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::483006a8712730b3d7094d43c14e1777
https://doi.org/10.1002/elps.201700175
https://doi.org/10.1002/elps.201700175