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Akademický článek

First insights in the metabolism of phosphate flame retardants and plasticizers using human liver fractions

Autor: Van den Eede, Nele, Maho, Walid, Erratico, Claudio, Neels, Hugo, Covaci, Adrian

Publikováno v: In Toxicology Letters 23 October 2013 223(1):9-15

Biotransformation of three phosphate flame retardants and plasticizers in primary human hepatocytes : untargeted metabolite screening and quantitative assessment

Autor: Van den Eede, Nele, De Meester, Ingrid, Maho, Walid, Neels, Hugo, Covaci, Adrian

Publikováno v: Journal of applied toxicology

Tris(2-butoxyethyl) phosphate (TBOEP), triphenyl phosphate (TPHP) and tris(1-chloro-2-propyl) phosphate (TCIPP) are current high-volume organophosphate flame retardants/plasticizers (PFRs) and are abundant in the indoor environment. While recent in v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2097::0f4b8dcb6202f477dea3f1f696f4aa08
https://hdl.handle.net/10067/1433540151162165141

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Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part 2 : zebrafish

Autor: Stinckens, Evelyn, Vergauwen, Lucia, Schroeder, Anthony L., Maho, Walid, Blackwell, Brett R., Witters, Hilda, Blust, Ronny, Ankley, Gerald T., Covaci, Adrian, Villeneuve, Daniel L., Knapen, Dries

Publikováno v: Aquatic toxicology

Disruption of the thyroid hormone (TH) system, an important mode of action, can lead to ecologically relevant adverse outcomes, especially during embryonic development. The present study characterizes the effects of disruption of TH synthesis on swim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2097::b56ee9a602a989bf9bc7d54697d0512b
https://hdl.handle.net/10067/1314080151162165141

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Phenotypic and biomarker evaluation of zebrafish larvae as an alternative model to predict mammalian hepatotoxicity

Autor: Verstraelen, Sandra, Peers, Bernard, Maho, Walid, Hollanders, Karen, Remy, Sylvie, Berckmans, Pascale, Covaci, Adrian, Witters, Hilda

Publikováno v: Journal of applied toxicology

Zebrafish phenotypic assays have shown promise to assess human hepatotoxicity, though scoring of liver morphology remains subjective and difficult to standardize. Liver toxicity in zebrafish larvae at 5days was assessed using gene expression as the b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2097::3d3838d55d5e897e911a36b57d533a27
https://hdl.handle.net/10067/1334540151162165141

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Sewage-based epidemiology in monitoring the use of new psychoactive substances: Validation and application of an analytical method using LC-MS/MS

Autor: Kinyua, Juliet, Covaci, Adrian, Maho, Walid, McCall, Ann-Kathrin, Neels, Hugo, van Nuijs, Alexander

Publikováno v: Drug testing and analysis

Sewage-based epidemiology (SBE) employs the analysis of sewage to detect and quantify drug use within a community. While SBE has been applied repeatedly for the estimation of classical illicit drugs, only few studies investigated new psychoactive sub

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2097::cd09545fff8c1f22d8f737aa790785eb
https://hdl.handle.net/10067/1250390151162165141

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Akademický článek

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