Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mahmut Mijit"'
Autor:
Mahmut Mijit, Megan Boner, Ricardo A. Cordova, Silpa Gampala, Eyram Kpenu, Angela J. Klunk, Chi Zhang, MarK R. Kelley, Kirk A. Staschke, Melissa L. Fishel
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Pancreatic cancer or pancreatic ductal adenocarcinoma (PDAC) is characterized by a profound inflammatory tumor microenvironment (TME) with high heterogeneity, metastatic propensity, and extreme hypoxia. The integrated stress response (ISR) pathway fe
Externí odkaz:
https://doaj.org/article/d25c860400e64157b704006bfbcbeda1
Autor:
Mahmut Mijit, Randall Wireman, Lee Armstrong, Silpa Gampala, Zonera Hassan, Christian Schneeweis, Guenter Schneider, Chi Zhang, Melissa L. Fishel, Mark R. Kelley
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers with a poor response to current treatment regimens. The multifunctional DNA repair-redox signaling protein Ref-1 has a redox signaling function that activates several transcripti
Externí odkaz:
https://doaj.org/article/98cb02dc3d834271aee89357a5bf59d2
Publikováno v:
Journal of Integrative Agriculture, Vol 16, Iss 6, Pp 1417-1421 (2017)
The common fig (Ficus carica L.) was one of the earliest horticultural crops to be domesticated. A number of different viruses can infect fig trees including Fig mosaic virus (FMV) that has been detected in several commercial fig trees in Xinjiang, C
Externí odkaz:
https://doaj.org/article/0c3d5d380e9f42688df08324f202d231
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 420 (2020)
The p53 transcription factor plays a critical role in cellular responses to stress. Its activation in response to DNA damage leads to cell growth arrest, allowing for DNA repair, or directs cellular senescence or apoptosis, thereby maintaining genome
Externí odkaz:
https://doaj.org/article/9508d27e02c84dc7b70a74932d081e83
Autor:
Silvano Junior Santini, Valeria Cordone, Mahmut Mijit, Virginio Bignotti, Pierpaolo Aimola, Vincenza Dolo, Stefano Falone, Fernanda Amicarelli
Publikováno v:
Antioxidants, Vol 8, Iss 9, p 346 (2019)
Uncontrolled accumulation of methylglyoxal (MG) and reactive oxygen species (ROS) occurs in hyperglycemia-induced endothelial dysfunction associated with diabetes. Resveratrol (RSV) protects the endothelium upon high glucose (HG); however, the mechan
Externí odkaz:
https://doaj.org/article/697a2add73a345d9abe6ffdeb68be2fd
Autor:
Mahmut Mijit, Sheng Liu, Kamakshi Sishtla, Gabriella D. Hartman, Jun Wan, Timothy W. Corson, Mark R. Kelley
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1101
APE1/Ref-1 (apurinic/apyrimidinic endonuclease 1, APE1 or APEX1; redox factor-1, Ref-1) is a dual-functional enzyme with crucial roles in DNA repair, reduction/oxidation (redox) signaling, and RNA processing and metabolism. The redox function of Ref-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be586d2c077888c323b106350259df08
Autor:
Anbukkarasi Muniyandi, Gabriella D. Hartman, Yang Song, Mahmut Mijit, Mark R. Kelley, Timothy W. Corson
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. :JPET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::473520933d76fab39aa20e2c4369c1a2
https://doi.org/10.1124/jpet.122.001563
https://doi.org/10.1124/jpet.122.001563
Autor:
Melissa L. Fishel, Mahmut Mijit, Silpa Gampala, Rachel A. Caston, Jill C. Fehrenbacher, Mark R. Kelley
Publikováno v:
Journal of cellular signaling
In the realm of DNA repair, base excision repair (BER) protein, APE1/Ref-1 (Apurinic/Apyrimidinic Endonuclease 1/Redox Effector - 1, also called APE1) has been studied for decades. However, over the past decade, APE1 has been established as a key pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b4aba68394dbda8ce5b026c069136e
https://pubmed.ncbi.nlm.nih.gov/34557865
https://pubmed.ncbi.nlm.nih.gov/34557865
Autor:
Mahmut Mijit, Olivia Babb, Silpa Gampala, Randall Wireman, Millie M. Georgiadis, Melissa L. Fishel, Mark R. Kelley
Publikováno v:
Cancer Research. 82:2366-2366
Ref-1/APE1 (Redox factor-1, Ref-1; Apurinic/apyrimidinic endonuclease 1, APE1) is a redox signaling enzyme that biochemically converts several transcription factors (TFs), such as NF-kB, STAT3, HIF-1α from an oxidized to a reduced state, allowing TF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::268ac1fdd7c0bf42fb55b925cdf29ac6
https://doi.org/10.1158/1538-7445.am2022-2366
https://doi.org/10.1158/1538-7445.am2022-2366
