Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mahmut Gozelle"'
Numerous studies have demonstrated that the aberrant enzymatic activity of SIRTs has been linked to various diseases like diabetes, cancer, inflammation, cardiovascular diseases, neurodegenerative disorders and therefore, the modulation of SIRTs is o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3a8bb0d4ca4acb1e93b1eb5afdc66d
https://avesis.gazi.edu.tr/publication/details/37c47753-e89c-4d81-a33d-fb5ab650a89d/oai
https://avesis.gazi.edu.tr/publication/details/37c47753-e89c-4d81-a33d-fb5ab650a89d/oai
Autor:
Mahmut Gozelle, Selen Gozde Kaya, Ahmet Bugra Aksel, Erva Ozkan, Filiz Bakar-Ates, Yesim Ozkan, Gokcen Eren
Publikováno v:
Bioorganic chemistry. 123
Sirtuin 2 (SIRT2), member of sirtuin family, belongs to class III histone deacetylases (HDACs) and is majorly cytosolic with occasional nuclear translocation. The enzymatic activity of SIRT2 is dependent on nicotinamide adenine dinucleotide (NAD+) an
Autor:
Filiz Bakar-Ates, Ahmet Bugra Aksel, Gokcen Eren, Semih Yagci, Yasemin Dündar, Mahmut Gozelle, Selen Gozde Kaya, Yeşim Özkan
Publikováno v:
Bioorganicmedicinal chemistry. 30
Sirtuins (SIRTs) are a class of nicotinamide adenine dinucleotide (NAD+)-dependent protein histone deacetylases (HDACs) that are evolutionarily conserved from bacteria to mammals. This group of enzymes catalyses the reversible deacetylation of lysine
Autor:
Selen Gozde Kaya, Mahmut Gozelle, Gokcen Eren, Rengul Cetin-Atalay, Agostino Bruno, Sezen Guntekin-Ergun, Gabriele Costantino, Yeşim Özkan, Fikriye Ozgencil
Sirtuins (SIRTs) are a class of NAD(+)-dependent protein histone deacetylases (HDACs) that catalyse the reversible deacetylation of lysine residues in the histones or non-histone substrates. Mammalian sirtuins consist of seven isoforms (SIRT1-7), whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9790623b37409cbc58b3b3f6bb71d34f
https://avesis.gazi.edu.tr/publication/details/4a26d71b-a9cf-492e-8ab6-24edd78bc9ba/oai
https://avesis.gazi.edu.tr/publication/details/4a26d71b-a9cf-492e-8ab6-24edd78bc9ba/oai
Autor:
Güldeniz Selmanoğlu, Leyla Açık, Nagehan Ramazanoğlu, Fatma Gümüş, Aysun Kılıç Süloğlu, Mahmut Gozelle
The aim of this study was to synthesize and evaluate the cytotoxic activities and plasmid DNA interaction of some new platinum(II) complexes, which may have potent cytotoxic activity and low side effects, with benzimidazole derivatives containing som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803aed2a099fa79a67f58d1cb70d631e
https://avesis.gazi.edu.tr/publication/details/a69cb9f2-214f-455e-931a-992b6212b71c/oai
https://avesis.gazi.edu.tr/publication/details/a69cb9f2-214f-455e-931a-992b6212b71c/oai