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Akademický článek

Large language models in medicine: A review of current clinical trials across healthcare applications.

Autor: Mahmud Omar, Girish N Nadkarni, Eyal Klang, Benjamin S Glicksberg

Publikováno v: PLOS Digital Health, Vol 3, Iss 11, p e0000662 (2024)

This review analyzes current clinical trials investigating large language models' (LLMs) applications in healthcare. We identified 27 trials (5 published and 22 ongoing) across 4 main clinical applications: patient care, data handling, decision suppo

Externí odkaz: https://doaj.org/article/dea632e5837f453b92c95f04aa2b3e04

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Akademický článek

Applications of large language models in psychiatry: a systematic review

Autor: Mahmud Omar, Shelly Soffer, Alexander W. Charney, Isotta Landi, Girish N. Nadkarni, Eyal Klang

Publikováno v: Frontiers in Psychiatry, Vol 15 (2024)

BackgroundWith their unmatched ability to interpret and engage with human language and context, large language models (LLMs) hint at the potential to bridge AI and human cognitive processes. This review explores the current application of LLMs, such

Externí odkaz: https://doaj.org/article/d9e1dd773a334da983bfae6ba1f3cfd4

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Akademický článek

Limited Clinical Impact of Genetic Associations between Celiac Disease and Type 2 Inflammatory Diseases: Insights from Mendelian Randomization

Autor: Mahmud Omar, Mohammad Omar, Salih Nassar, Adi Lahat, Kassem Sharif

Publikováno v: Biomedicines, Vol 12, Iss 7, p 1429 (2024)

Background: Celiac disease, a gluten-triggered autoimmune disorder, is known for its systemic inflammatory effects. Its genetic associations with type 2 inflammatory diseases like asthma, allergic rhinitis, and atopic dermatitis remain unclear, promp

Externí odkaz: https://doaj.org/article/cc040fe779894eba924f43ecd4c85068

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Akademický článek

The association between psoriasis, psoriasis severity, and inflammatory bowel disease: a population-based analysis

Autor: Uria Shani, Niv Ben-Shabat, Roula Qassem, Adi Lahat, Mahmud Omar, Einat Savin, Arad Dotan, Yonatan Shneor Patt, Lior Fisher, Galia Zacay, Howard Amital, Abdulla Watad, Kassem Sharif

Publikováno v: Therapeutic Advances in Gastroenterology, Vol 17 (2024)

Background: The skin–gut axis, characterized by bidirectional communication between the skin and gut, plays a crucial role in the pathogenesis of psoriasis and inflammatory bowel diseases (IBD). Objectives: We aimed to explore the association betwe

Externí odkaz: https://doaj.org/article/cd18f0c324224905871e33146b9e575a

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Akademický článek

A comparative systematic review and meta-analysis on the diagnostic accuracy of non-invasive tests for Helicobacter pylori detection in elderly patients

Autor: Mahmud Omar, Razi Abu-Salah, Reem Agbareia, Yusra Sharif, Roni Levin, Adi Lahat, Kassem Sharif

Publikováno v: Frontiers in Medicine, Vol 10 (2023)

BackgroundHelicobacter pylori (H. pylori) infection, a type I carcinogen, affects approximately 50% of the global population, correlating with various gastric pathologies. Notably, diagnostic sensitivities of non-invasive methods, such as the stool a

Externí odkaz: https://doaj.org/article/8b537248764649cc8963bb7e75728dcd

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Akademický článek

Big data- and machine learning-based analysis of a global pharmacovigilance database enables the discovery of sex-specific differences in the safety profile of dual IL4/IL13 blockade

Autor: Kassem Sharif, Mahmud Omar, Adi Lahat, Yonatan Shneor Patt, Howard Amital, Ghanem Zoabi, Nicola Luigi Bragazzi, Abdulla Watad

Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)

Background: Due to its apparent efficacy and safety, dupilumab, a monoclonal antibody that blocks Interleukin 4 (IL-4) and Interleukin 13 (IL-13), has been approved for treating T-helper 2 (Th2) disorders. However, adverse effects like local injectio

Externí odkaz: https://doaj.org/article/d03e373e545541db8fae7077780f1270

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