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pro vyhledávání: '"Mahmoud-Sobhy Elkhwanky"'
Autor:
Mahmoud‐Sobhy Elkhwanky, Outi Kummu, Terhi T Piltonen, Johanna Laru, Laure Morin‐Papunen, Maija Mutikainen, Pasi Tavi, Jukka Hakkola
Publikováno v:
JBMR Plus, Vol 4, Iss 11, Pp n/a-n/a (2020)
ABSTRACT Low plasma level of 25‐hydroxyvitamin D (25‐OH‐D), namely vitamin D deficiency, is associated with obesity and weight loss improves 25‐OH‐D status. However, the mechanism behind obesity‐induced vitamin D deficiency remains unclea
Externí odkaz:
https://doaj.org/article/ee275ba5f3e9401eabbd816a6d2460fb
Publikováno v:
Endocrinology. 163
Vitamin D deficiency [ie, low plasma 25-hydroxyvitamin D (25-OH-D)] associates with the prevalence of metabolic diseases including type 1 diabetes; however, the molecular mechanisms are incompletely understood. Recent studies have indicated that both
Autor:
Jukka Hakkola, Maija Mutikainen, Terhi Piltonen, Laure Morin-Papunen, Johanna Laru, Pasi Tavi, Outi Kummu, Mahmoud-Sobhy Elkhwanky
Publikováno v:
JBMR Plus
JBMR Plus, Vol 4, Iss 11, Pp n/a-n/a (2020)
JBMR Plus, Vol 4, Iss 11, Pp n/a-n/a (2020)
Low plasma level of 25‐hydroxyvitamin D (25‐OH‐D), namely vitamin D deficiency, is associated with obesity and weight loss improves 25‐OH‐D status. However, the mechanism behind obesity‐induced vitamin D deficiency remains unclear. Here,
Autor:
Mahmoud-Sobhy Elkhwanky, Valtteri Rinne, Pirkko Viitala, Kari T. Chambers, Mikko Karpale, Maija Mutikainen, Jukka Hakkola, Marcin Buler, Rudolf J. Wiesner, Brian N. Finck, Sanna-Mari Aatsinki, Pasi Tavi, Outi Kummu, Andras Franko
Publikováno v:
Diabetes
Low 25-hydroxyvitamin D levels correlate with the prevalence of diabetes; however, the mechanisms remain uncertain. Here, we show that nutritional deprivation–responsive mechanisms regulate vitamin D metabolism. Both fasting and diabetes suppressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e40bf2d2a1fe4f85857545d87610e3e
https://europepmc.org/articles/PMC6477896/
https://europepmc.org/articles/PMC6477896/
Autor:
Jukka Hakkola, Mahmoud-Sobhy Elkhwanky
Publikováno v:
Antioxidantsredox signaling. 28(8)
Extranuclear sirtuins in cytosol (SIRT2) and mitochondria (SIRT3, SIRT4, and SIRT5) are key regulators of metabolic enzymes and the antioxidative defense mechanisms. They play an important role in the adjustment of metabolic pathways in alterations o