Výsledky vyhledávání - "Mahmoud Teaima"

Akademický článek

Merging konjac glucomannan with other copolymeric hydrogels as a cutting-edge liquid raft system for dual delivery of etoricoxib and famotidine

Autor: Nabil A. Shoman, Marwa Saady, Mahmoud Teaima, Rehab Abdelmonem, Mohamed A. El-Nabarawi, Sammar Fathy Elhabal

Publikováno v: Drug Delivery, Vol 30, Iss 1 (2023)

AbstractThis study aimed to formulate and evaluate a floating raft system for the co-delivery of etoricoxib (ETO) and famotidine (FAM) using a combination of glucomannan with natural/semi-synthetic polysaccharides. Formulation variables affect gelati

Externí odkaz: https://doaj.org/article/bfe30ce66bd04164943de6d3e58077a9

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Akademický článek

Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances

Autor: Khaled Mahmoud, Shady Swidan, Mohamed El-Nabarawi, Mahmoud Teaima

Publikováno v: Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-42 (2022)

Abstract Liver cancer is considered one of the deadliest diseases with one of the highest disease burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is considered to be the most common type. Multiple conventional a

Externí odkaz: https://doaj.org/article/f587d1db428c43c381aa7b8b0f3128b6

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Akademický článek

A Comparative Study on Cyclodextrin Derivatives in Improving Oral Bioavailability of Etoricoxib as a Model Drug: Formulation and Evaluation of Solid Dispersion-Based Fast-Dissolving Tablets

Autor: Doaa Elsegaie, Mohamed A. El-Nabarawi, Hanaa Abdelmonem Mahmoud, Mahmoud Teaima, Dina Louis

Publikováno v: Biomedicines, Vol 11, Iss 9, p 2440 (2023)

Etoricoxib, as a model drug, has a poor solubility and dissolution rate. Cyclodextrin derivatives can be used to solve such a problem. A comparative study was run on three cyclodextrin derivatives, namely β-CD, HP β-CD, and SBE β-CD, to solve the

Externí odkaz: https://doaj.org/article/13a33a51267c499898ca646b189a3117

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Akademický článek

Development of Pomegranate Extract-Loaded Solid Lipid Nanoparticles: Quality by Design Approach to Screen the Variables Affecting the Quality Attributes and Characterization

Autor: Noha Badawi, Khalid El-Say, Dalia Attia, Mohamed El-Nabarawi, Mohey Elmazar, Mahmoud Teaima

Publikováno v: ACS Omega, Vol 5, Iss 34, Pp 21712-21721 (2020)

Externí odkaz: https://doaj.org/article/a7c2ca3c335444c187d1c02f1103eb49

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Akademický článek

Construction of sublingual trilaminated Eszopiclone fast dissolving film for the treatment of Insomnia: Formulation, characterization and In vivo clinical comparative pharmacokinetic study in healthy human subjects.

Autor: Mahmoud Teaima, Mohamed Yasser, Nehal Elfar, Kamel Shoueir, Mohamed El-Nabarawi, Doaa Helal

Publikováno v: PLoS ONE, Vol 17, Iss 6, p e0266019 (2022)

BackgroundDisturbed sleep can cause to m health problems such as cognitive impairment, depressed mood, and negative effects on cardiovascular, endocrine, and immune function. This study formulates and optimizes Eszopiclone trilaminate fast dissolving

Externí odkaz: https://doaj.org/article/e8e6bcbe892c4489aa2dd934b1054349

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Akademický článek

Oral Bioavailability Enhancement of Vancomycin Hydrochloride with Cationic Nanocarrier (Leciplex): Optimization, In Vitro, Ex Vivo, and In Vivo Studies

Autor: Menna M. Abdellatif, Sara Mohamed Ahmed, Mohamed A. El-Nabarawi, Mahmoud Teaima

Publikováno v: Scientia Pharmaceutica, Vol 91, Iss 1, p 1 (2022)

To explore the performance of the cationic nanocarrier leciplex (LPX) in escalating the oral bioavailability of vancomycin hydrochloride (VAN) by promoting its intestinal permeability. With the aid of a D-optimal design, the effect of numerous factor

Externí odkaz: https://doaj.org/article/b0cefa41714440b3bcaac6249da2c536

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Akademický článek

Sertaconazole-Nitrate-Loaded Leciplex for Treating Keratomycosis: Optimization Using D-Optimal Design and In Vitro, Ex Vivo, and In Vivo Studies

Autor: Menna M. Abdellatif, Mina Josef, Mohamed A. El-Nabarawi, Mahmoud Teaima

Publikováno v: Pharmaceutics, Vol 14, Iss 10, p 2215 (2022)

This study aims to develop efficient topical therapy for keratomycosis using sertaconazolenitrate (STZN)-loaded leciplex (LP). The D-optimal design was used to optimize STZN-loaded LP by utilizing soy phosphatidylcholine (SPC) molar ratio (X1), catio

Externí odkaz: https://doaj.org/article/8878604c5004487f919dcd680cea91cd

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Akademický článek

Design and Optimization of Pioglitazone Hydrochloride Self-Nanoemulsifying Drug Delivery System (SNEDDS) Incorporated into an Orally Disintegrating Tablet

Autor: Mahmoud Teaima, Sandra Hababeh, Mai Khanfar, Fares Alanazi, Doaa Alshora, Mohammed El-Nabarawi

Publikováno v: Pharmaceutics, Vol 14, Iss 2, p 425 (2022)

Pioglitazone Hydrochloride (PGZ) suffers from poor aqueous solubility. The aim of this research was to design orally disintegrating tablets with self-nanoemulsifying properties (T-SNEDDS) to improve the Pioglitazone solubility and dissolution rate. T

Externí odkaz: https://doaj.org/article/bec5ac51f5c8405f90930260605bf9d7

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NANO-DELIVERY SYSTEMS FOR ENHANCING ORAL BIOAVAILABILITY OF DRUGS

Autor: MENNA M. ABDELLATIF, SARA MOHAMED AHMED, MOHAMED A. EL-NABARAWI, MAHMOUD TEAIMA

Publikováno v: International Journal of Applied Pharmaceutics. :13-19

The two main issues impacting oral delivery are drug solubility and permeability. The FDA adopted the Biopharmaceutics Classification System (BCS) in 2000. The BCS categorizes drugs into four classes based on their solubility and permeability. For pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0120f4a77551836f4cfe35e4e26d66e5
https://doi.org/10.22159/ijap.2023v15i1.46758

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