Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mahmoud Shobair"'
Publikováno v:
Chemical Research in Toxicology. 36:230-242
Autor:
K Nadira, De Abrew, Ted, Natoli, Cathy C, Lester, Xiaohong, Wang, Mahmoud, Shobair, Arvind, Subramanian, George P, Daston
Publikováno v:
Toxicological Sciences. 190:227-241
Butylated hydroxytoluene (BHT) is a synthetic antioxidant widely used in many industrial sectors. BHT is a well-studied compound for which there are many favorable regulatory decisions. However, a recent opinion by the French Agency for Food, Environ
Publikováno v:
Environmental Science: Processes & Impacts.
Mixture toxicity literature is dominated by water pollutants, pesticides, environmental pollutants, insecticides, soil pollutants, and chemicals described as persistent, bioaccumulative, and toxic.
Autor:
Mahmoud Shobair, Susan C. Laws, Ashley S. Murr, Tammy E. Stoker, Ryan Lougee, Daniel R. Hallinger, Angela R. Buckalew, Jun Wang, Ann M. Richard
Publikováno v:
Arch Toxicol
The sodium-iodide symporter (NIS) mediates the uptake of iodide into the thyroid. Inhibition of NIS function by xenobiotics has been demonstrated to suppress circulating thyroid hormones and perturb related physiological functions. Until recently, fe
Autor:
John R. Bucher, Mahmoud Shobair, Paul Shinn, Adam Yasgar, Inthirany Thillainadarajah, Chihae Yang, Richard S. Paules, Bradley J. Collins, Ann M. Richard, Anton Simeonov, Ruili Huang, Suzanne Fitzpatrick, Kevin M. Crofton, Keith A. Houck, Robert J. Kavlock, Christopher M. Grulke, Suramya Waidyanatha, James F. Rathman, Raymond R. Tice, Ryan Lougee, Richard S. Judson, Christopher P. Austin, Russell S. Thomas, Antony J. Williams
Publikováno v:
Chem Res Toxicol
[Image: see text] Since 2009, the Tox21 project has screened ∼8500 chemicals in more than 70 high-throughput assays, generating upward of 100 million data points, with all data publicly available through partner websites at the United States Enviro
Autor:
Mahmoud Shobair, Grace Patlewicz, Alexander Medvedev, Barbara A. Wetmore, Keith A. Houck, Sergei S. Makarov, M. Scott Clifton, Marci Smeltz, Antony J. Williams, Ann M. Richard
Publikováno v:
Toxicology. 457:152789
Per- and polyfluoroalkyl substances (PFAS) are a broad class of hundreds of fluorinated chemicals with environmental health concerns due to their widespread presence and persistence in the environment. Several of these chemicals have been comprehensi
Autor:
Mahmoud Shobair, M. Jackson Stutts, Pradeep Kota, Yan L. Dang, Hong He, Onur Dagliyan, Nikolay V. Dokholyan
Sodium absorption in epithelial cells is rate-limited by the epithelial sodium channel (ENaC) activity in lung, kidney, and the distal colon. Pathophysiological conditions, such as cystic fibrosis and Liddle syndrome, result from water-electrolyte im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b62f3b3856baa1be4bfe580c0d4c091
Publikováno v:
Biophysical Journal. 106:285a
RNA can fold into complex tertiary structures, much like proteins, and exhibits significant conformational dynamics that are a central facet of its functions. Two limiting types of RNA motions occur: equilibrium fluctuations and induced conformationa
Publikováno v:
Biophysical Journal. 102:732a
Telomerase is a special reverse transcriptase that adds repetitive DNA sequences, GGGTTG for Tetrahymena thermophila, at the 3’ end of DNA strand in the telomere region to ensure DNA replication completion. This enzyme is a ribonucleoprotein comple