Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mahmoud Mahmoudian"'
Autor:
Fatemeh Yari, Fatemeh Sabaghi, Nadia Bagheri, Maryam Zaman Vaziri, Maryam Sobhani, Zohreh Sharifi, Mahmoud Mahmoudian Shooshtari
Publikováno v:
Cell Journal, Vol 11, Iss 1, Pp 62-62 (2009)
Rodgers (Rg) and Chido (Ch) are blood-group antigens and they determine the fourthcomponentof human complement C4. Rodgers and Chido are associated with two C4isotypes (C4A and C4B). In addition to genotype determination, study on expression ofRg and
Externí odkaz:
https://doaj.org/article/cf32a8351b654d5590cd15837070895b
Publikováno v:
Angewandte Chemie. 114:3309-3312
Autor:
Simon J. F. Macdonald, Mahmoud Mahmoudian, Ian B. Campbell, Mike S. Anson, Phil J. Borman, Nicolas Millot
Publikováno v:
Organic Process Research & Development. 6:463-470
Infrared thermography (IRT) is presented as a novel technique to screen a potentially large number of asymmetric catalysts or substrates in a high-throughput fashion. IRT was used as a simple, rapi...
Autor:
Mahmoud Mahmoudian
Publikováno v:
Biocatalysis and Biotransformation. 18:105-118
Biocatalytic production of several key chiral intermediates in the synthesis of anti-inflammatory, anti-viral and anti-leukaemic agents is described. These include (i) a nucleoside oxidase from Stenotrophomonas maltophilia to oxidise unnatural purine
Autor:
Andrew Lowdon, Michael J. Dawson, Martin Francis Jones, Wallis Christopher John, Mahmoud Mahmoudian
Publikováno v:
Tetrahedron: Asymmetry. 10:1201-1206
A simple and efficient process for the enantioselective resolution of N-substituted 2-azabicyclo[2.2.1]hept-5-en-3-one has been developed using commercially available hydrolytic enzymes. This offers a practical approach for the preparation of enantio
Autor:
Michael J. Dawson, Mahmoud Mahmoudian, Nicholas J. Turner, Gareth N. Jenkins, Chris S. Drake, Malcolm Chandler, Brian A.M. Rudd, Richard M. Hall, Livermore David, Paul Stead, Brian Cox
Publikováno v:
Tetrahedron. 54:8171-8182
The nucleoside oxidase from Stenotrophomonas maltophilia (FERM BP-2252) has been used to generate 5′-carboxylic acid derivatives of nucleoside analogues. The enzyme, which has a surprisingly broad substrate specificity for unnatural nucleosides, ha
Autor:
David Noble, Stanley M. Roberts, Graham Webb, Tino Rossi, Hugh Marley, Michael J. Dawson, Yam To Ip, Paul Stead, Elisabetta Piga, Mahmoud Mahmoudian
Publikováno v:
Tetrahedron: Asymmetry. 7:2247-2250
Enzymatic and chemical resolution methods suitable for preparation of multi-kg quantities of (+)-(1S,2S)-2-methoxycyclohexanol from (+/−) trans-2-methoxycyclohexanol have been developed. The enzymatic resolution was found to offer a particularly si
Publikováno v:
Tetrahedron: Asymmetry. 6:393-396
A number of commercially available lipases and proteases was screened for the ability to hydrolyse enantioselectively racemic oxathiolane 2. Mucor miehei lipase was identified as the most efficient biocatalyst. Bioconversion of 2 afforded enantiomeri
Autor:
Steven L. Sollis, Mahmoud Mahmoudian, Paul W. Smith, Ian D. Starkey, David Noble, Peter C. Cherry, Peter D. Howes
Publikováno v:
Tetrahedron Letters. 36:299-302
The title compound 2b has been synthesised in 8 steps from 2-deoxy-D-glucose (2-DG). Key transformations were an aldolase reaction utilising 2-DG to form the 9 carbon sugar 3 , and then introduction of the required unsaturation and a 4-amino substitu
Autor:
Mahmoud Mahmoudian, Michael J. Dawson, C.S. Drake, D.S. Montgomery, G.C. Lawrence, I.J. Purvis, R.S. Hale, J.E. Piercey, R. Storer, P. Jones, B.S. Baines
Publikováno v:
Enzyme and Microbial Technology. 15:749-755
Although equipotent in terms of antiviral activity, the two enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) differ markedly in their cytotoxicity. (2'R-cis)-2'-deoxy-3'-thiacytidine (3TC) is substantially less toxic than its optical antipode, and i