Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mahmoud M. Sheha"'
Autor:
Mohamed T-E Maghraby, Tahani Mazyad Almutairi, Stefan Bräse, Ola I. A. Salem, Bahaa G. M. Youssif, Mahmoud M. Sheha
Publikováno v:
Molecules, Vol 28, Iss 20, p 7092 (2023)
A novel series of 1,2,3-triazole/1,2,4-triazole hybrids 5a, 5b, and 6a–i was designed and synthesized as antiproliferative agents targeting aromatase enzymes. The antiproliferative activity of the new hybrids against four cancer cells was studied u
Externí odkaz:
https://doaj.org/article/d69cdec56a2b4d09b4ee4f53cf6c8370
Publikováno v:
Chemical Biology & Drug Design. 101:749-759
A novel series of 1,2,3-triazole/chalcone hybrids 6a-n was designed and synthesized using a molecular hybridization approach to develop a new cytotoxic agent capable of targeting epidermal growth factor receptor (EGFR) and/or BRAF. The antiproliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04bef2017024b0cbb6a8dad4b0b999f4
https://doi.org/10.1111/cbdd.14178
https://doi.org/10.1111/cbdd.14178
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Currently, all available antiviral drugs against influenza virus (IV) that target the virus proteins directly, like Baloxavir acid (BXA), lead to viral resistance. Therefore, cellular mechanisms and factors essential for IV replication are promising
Externí odkaz:
https://doaj.org/article/4681e8d539be46be902ee210f76b6639
Autor:
Mahmoud M. Shehata, Sara H. Mahmoud, Mohammad Tarek, Ahmed A. Al-Karmalawy, Amal Mahmoud, Ahmed Mostafa, Mahmoud M. Elhefnawi, Mohamed A. Ali
Publikováno v:
Molecules, Vol 26, Iss 20, p 6182 (2021)
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, the causative agent of coronavirus disease (COVID-19)) has caused relatively high mortality rates in humans throughout the world since its first detection in late December 2019, leading to
Externí odkaz:
https://doaj.org/article/3fefbfdc22364709b0c50a9e56925b78
Autor:
Mahmoud M. Shehata, Daniel K.W. Chu, Mokhtar R. Gomaa, Mounir AbiSaid, Rabeh El Shesheny, Ahmed Kandeil, Ola Bagato, Samuel M.S. Chan, Elie K. Barbour, Houssam S. Shaib, Pamela McKenzie, Richard Webby, Mohamed A. Ali, Myoung-don Oh, Ghazi Kayali
Publikováno v:
Emerging Infectious Diseases, Vol 22, Iss 1, Pp 148-150 (2016)
Externí odkaz:
https://doaj.org/article/41475286869646b6ba48c9b677592dad
Autor:
Daniel K.W. Chu, Leo L.M. Poon, Mokhtar M. Gomaa, Mahmoud M. Shehata, Ranawaka A.P.M. Perera, Dina Abu Zeid, Amira S. El Rifay, Lewis Y. Siu, Yi Guan, Richard J. Webby, Mohamed A. Ali, Malik Peiris, Ghazi Kayali
Publikováno v:
Emerging Infectious Diseases, Vol 20, Iss 6, Pp 1049-1053 (2014)
We identified the near-full-genome sequence (29,908 nt, >99%) of Middle East respiratory syndrome coronavirus (MERS-CoV) from a nasal swab specimen from a dromedary camel in Egypt. We found that viruses genetically very similar to human MERS-CoV are
Externí odkaz:
https://doaj.org/article/b37f11851ff94d6bb716a1dd9e58a398
Autor:
Ghazi Kayali, Ahmed Kandeil, Rabeh El-Shesheny, Ahmed S. Kayed, Mokhtar M. Gomaa, Asmaa M. Maatouq, Mahmoud M. Shehata, Yassmin Moatasim, Ola Bagato, Zhipeng Cai, Adam Rubrum, Mohamed A. Kutkat, Pamela P. McKenzie, Robert G. Webster, Richard J. Webby, Mohamed A. Ali
Publikováno v:
Emerging Infectious Diseases, Vol 20, Iss 4, Pp 542-551 (2014)
Continuous circulation of influenza A(H5N1) virus among poultry in Egypt has created an epicenter in which the viruses evolve into newer subclades and continue to cause disease in humans. To detect influenza viruses in Egypt, since 2009 we have activ
Externí odkaz:
https://doaj.org/article/89c89c14a39842f2abb888c95107036f
Autor:
Ahmed Kandeil, Mokhtar Gomaa, Ahmed Nageh, Mahmoud M. Shehata, Ahmed E. Kayed, Jamal S. M. Sabir, Awatef Abiadh, Jamel Jrijer, Zuhair Amr, Mounir Abi Said, Denis K. Byarugaba, Fred Wabwire-Mangen, Titus Tugume, Nadira S. Mohamed, Roba Attar, Sabah M. Hassan, Sabah Abdulaziz Linjawi, Yassmin Moatassim, Omnia Kutkat, Sara Mahmoud, Ola Bagato, Noura M. Abo Shama, Rabeh El-Shesheny, Ahmed Mostafa, Ranawaka A. P. M. Perera, Daniel K. W. Chu, Nagla Hassan, Basma Elsokary, Ahmed Saad, Heba Sobhy, Ihab El Masry, Pamela P. McKenzie, Richard J. Webby, Malik Peiris, Yilma J. Makonnen, Mohamed A. Ali, Ghazi Kayali
Publikováno v:
Viruses, Vol 11, Iss 8, p 717 (2019)
Dromedary camels are the natural reservoirs of the Middle East respiratory syndrome coronavirus (MERS-CoV). Camels are mostly bred in East African countries then exported into Africa and Middle East for consumption. To understand the distribution of
Externí odkaz:
https://doaj.org/article/776bf01467154d0f8e24de0ccd4b6e8a
Autor:
Mahmoud M. Shehata, Ahmed Mostafa, Lisa Teubner, Sara H. Mahmoud, Ahmed Kandeil, Rabeh Elshesheny, Thamer A. Boubak, Renate Frantz, Luigi La Pietra, Stephan Pleschka, Ahmed Osman, Ghazi Kayali, Trinad Chakraborty, Mohamed A. Ali, Mobarak Abu Mraheil
Publikováno v:
Vaccines, Vol 7, Iss 2, p 46 (2019)
Vaccination is the most functional medical intervention to prophylactically control severe diseases caused by human-to-human or animal-to-human transmissible viral pathogens. Annually, seasonal influenza epidemics attack human populations leading to
Externí odkaz:
https://doaj.org/article/bb777806aa19423ba0a848f1618c79d2
Autor:
Sheha M; Medicinal and Pharmaceutical Chemistry Department, College of Pharmacy, Assiut University, Assiut 71526, Egypt. sheha185@hotmail.com
Publikováno v:
Archives of pharmacal research [Arch Pharm Res] 2012 Mar; Vol. 35 (3), pp. 523-30. Date of Electronic Publication: 2012 Apr 05.