Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Mahmoud M. Ghorab"'
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 2, Iss 2, Pp 43-59 (2016)
Risperidone is effective in the treatment of positive as well as negative symptoms of schizophrenia. But, there is a strong correlation between plasma levels of risperidone and its adverse effects. Objective: This study aimed to develop risperidone i
Externí odkaz:
https://doaj.org/article/79a878fcb1164bfe87df30e8e378837d
Autor:
Salwa Salah, Hussein O. Ammar, Dina Mahmoud Mostafa, Eman Samy Shalaby, Sameh Hosam Abd El-Alim, Mahmoud M. Ghorab, Ahmed Alaa Kassem
Publikováno v:
Journal of Microencapsulation. 37:366-383
The present work is designed to achieve efficient localised skin delivery of folic acid (FA)–loaded nanostructured lipid carriers (NLCs) to infer efficient treatment of skin photoageing conditions ...
Publikováno v:
Journal of Drug Delivery Science and Technology. 52:236-247
Glaucoma, a chronic disease of elevated intraocular pressure, is considered as the first leading cause of blindness. Brimonidine tartrate (BRT), a hydrophilic drug with poor ocular bioavailability, is a glaucoma treatment that is used three times dai
Publikováno v:
Journal of Drug Delivery Science and Technology. 50:99-106
Purpose of this study is to develop a self-nano emulsifying drug delivery system (SNEDDS) to improve the dissolution of tadalafil and to overcome two formulation challenges namely, increasing the tadalafil solubility in the preconcentrate using a cos
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 509-521 (2019)
Drug Delivery
Drug Delivery
Brimonidine tartrate (BRT) is a hydrophilic α2 adrenergic agonist used for the treatment of glaucoma. Glaucoma is an ocular disease affecting the anterior segment of the eye requiring lifetime treatment. Owing to the obstacles facing ocular delivery
Publikováno v:
IEEE transactions on nanobioscience. 20(2)
A promising approach has been emerging to enhance dissolution of hydrophobicdrugsby encapsulation in mesoporous silica materials. Olanzapine is a practically insoluble antipsychotic drug which is subjected to excessive first pass effect and shows ina
Publikováno v:
AAPS PharmSciTech. 21(6)
In this research, we examined the effect of rosuvastatin calcium-loaded nanoparticles on the hair growth-promoting activity on Albino rats. Nanoparticles were prepared using 2:1 weight ratio of drug to methyl-β-cyclodextrin with 10, 20, and 30% stab
Publikováno v:
Journal of Drug Delivery Science and Technology. 47:151-158
The aim of the work was to improve carvedilol bioavailability through preparation of nanoparticles to be formulated as a buccoadhesive gel. Physicochemical compatibility of drug was studied. The ionic gelation technique was used for nanoparticles pre
Publikováno v:
International Journal of Pharmaceutical Sciences and Developmental Research. :009-019
Purpose: The aim of this study is to improvelow oral bioavailability of sertraline HCl by formulation and characterization ofsolid self-nanoemulsifying drug delivery system [SNEDDS] using spray drying technique.
Publikováno v:
Journal of Drug Delivery Science and Technology. 41:197-205
Tadalafil suffers from poor aqueous solubility that could lead to fluctuating blood levels and unreproducible effect. Thus, this work aimed at improving tadalafil dissolution utilizing the approach of surfactant-enriched tablets. The feasibility of m