Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Mahmoud M. El‐Mas"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Despite the established role of peripheral adenosine receptors in sepsis-induced organ dysfunction, little or no data is available on the interaction of central adenosine receptors with sepsis. The current study tested the hypothesis th
Externí odkaz:
https://doaj.org/article/b87cbeab7cfd4a778f2ffba87247a8a9
Autor:
Evans O. Ayieng’a, Elham A. Afify, Salwa A. Abuiessa, Samar S. Elblehi, Sahar M. El-Gowilly, Mahmoud M. El-Mas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Although pain and sepsis are comorbidities of intensive care units, reported data on whether pain control by opioid analgesics could alter inflammatory and end-organ damage caused by sepsis remain inconclusive. Here, we tested the hypothesis
Externí odkaz:
https://doaj.org/article/bcb5fa306eaf4d9db41adc7003ab51d4
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The cholinergic pathway plays a crucial role in improving inflammatory end-organ damage. Given the interplay between cholinergic and adenosinergic neurotransmission, we tested the hypothesis that central adenosine A1 receptors (A1ARs) modula
Externí odkaz:
https://doaj.org/article/7cefe149e1fd49478e74cde842e89efd
Autor:
Sherien A. Abdelhady, Mennatallah A. Ali, Dalia M. Yacout, Marwa M. Essawy, Lamia S. Kandil, Mahmoud M. El-Mas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Although nonsteroidal antiinflammatory drugs (NSAIDs) are frequently used for fever and pain during pregnancy, their possible interaction with perinatal renal injury induced by preeclampsia (PE) has not been addressed. Here, studies were und
Externí odkaz:
https://doaj.org/article/ac365318ca284078b0ba029d07989e5f
Autor:
Hagar A. Morgaan, Marwa Y. Sallam, Hanan M. El-Gowelli, Sahar M. El-Gowilly, Mahmoud M. El-Mas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract We recently reported exacerbated endotoxic signs of neuroinflammation and autonomic defects in offspring of preeclamptic (PE) dams. Here, we investigated whether PE programming similarly modifies hemodynamic and renal vasoconstrictor respons
Externí odkaz:
https://doaj.org/article/47c40974c3d34fdcb8c479a9bb4e1adf
Autor:
Hagar A. Morgaan, Marwa Y. Sallam, Hanan M. El-Gowelli, Sahar M. El-Gowilly, Mahmoud M. El-Mas
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Preeclampsia (PE) enhances the vulnerability of adult offspring to serious illnesses. The current study investigated whether preeclamptic fetal programming impacts hemodynamic and renal vasodilatory disturbances in endotoxic adult offsp
Externí odkaz:
https://doaj.org/article/577733778c734e84bad82019c637d6b0
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 1, Pp 127-135 (2020)
Widely different exposure times to endotoxic insults have been employed in reported studies. The current experimental study systematically evaluated the time-course and sex influences of endotoxic insult on survivability and cardiovascular and renal
Externí odkaz:
https://doaj.org/article/f7897d8951294f96add3d1ae653d5c1b
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Metabolic syndrome (MetS) is closely associated with the development of cardiovascular diseases. We recently developed a nano-preparation of the flavonoid quercetin (QU) in a self-nanoemulsifying drug delivery system (SNEDDS). The latter comprised a
Externí odkaz:
https://doaj.org/article/bdd1caddafde4bb0979bbd0caff28296
Autor:
Manar A. Serageldin, Amira B. Kassem, Yasser El-Kerm, Maged W. Helmy, Mahmoud M. El-Mas, Noha A. El-Bassiouny
Publikováno v:
Drug Safety. 46:587-599
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 395:1587-1598