Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mahmoud Abdul Karim"'
Publikováno v:
Molecular Biology of the Cell
Endosomal Na+(K+)/H+ exchangers (NHEs) are important for endocytosis but it is unclear how they contribute. A cell-free assay was used to show that the yeast NHE Nhx1 regulates multivesicular body–lysosome fusion, the last step of endocytosis, demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece090424d450c479f8a208235bcedea
http://europepmc.org/articles/PMC5996954
http://europepmc.org/articles/PMC5996954
Publikováno v:
Traffic. 19:138-149
When marked for degradation, surface receptor and transporter proteins are internalized and delivered to endosomes where they are packaged into intralumenal vesicles (ILVs). Many rounds of ILV formation create multivesicular bodies (MVBs) that fuse w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b11adfb58ba9dbf5b4ef9f69b021205
https://doi.org/10.1111/tra.12543
https://doi.org/10.1111/tra.12543
Publikováno v:
Molecular Biology of the Cell
When vacuolar lysosomes fuse, an intralumenal membrane fragment is produced and degraded by hydrolyses. How or why this fragment forms is not entirely understood. We show that the fusion machinery regulates stalk expansion during lipid bilayer fusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696e0c078e4a22714d0315b816a43df7
http://europepmc.org/articles/PMC5231899
http://europepmc.org/articles/PMC5231899
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1860
Endocytosis is a fundamental process underlying diverse eukaryotic physiology. The terminal stage of this process is membrane fusion between the perimeter membrane of a late endosome filled with intraluminal vesicles, or multivesicular body (MVB), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e60b2fb6b362a124248ea4e912727e7
https://pubmed.ncbi.nlm.nih.gov/30317513
https://pubmed.ncbi.nlm.nih.gov/30317513
Publikováno v:
Methods in Molecular Biology ISBN: 9781493987597
Endocytosis is a fundamental process underlying diverse eukaryotic physiology. The terminal stage of this process is membrane fusion between the perimeter membrane of a late endosome filled with intraluminal vesicles, or multivesicular body (MVB), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ac7bc2cf8b8bc920bb1d9926e725c12
https://doi.org/10.1007/978-1-4939-8760-3_19
https://doi.org/10.1007/978-1-4939-8760-3_19
Loss-of-function mutations in human endosomal Na+(K+)/H+ Exchangers (NHEs) NHE6 and NHE9 are implicated in neurological disorders including Christianson Syndrome, autism and attention deficit and hyperactivity disorder (ADHD). These mutations disrupt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f00156499892a4a62ec8d0f2eafa94e
Publikováno v:
Developmental cell. 40(2)
Lysosomes rely on their resident transporter proteins to return products of catabolism to the cell for reuse and for cellular signaling, metal storage, and maintaining the lumenal environment. Despite their importance, little is known about the lifet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730357a62eadc5f2d7642d84deb9e93a
https://pubmed.ncbi.nlm.nih.gov/28017618
https://pubmed.ncbi.nlm.nih.gov/28017618
Publikováno v:
Developmental Cell. 47:80-97.e6
Summary Upon vacuolar lysosome (or vacuole) fusion in S. cerevisiae, a portion of membrane is internalized and catabolized. Formation of this intralumenal fragment (ILF) is important for organelle protein and lipid homeostasis and remodeling. But how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ae80866cc52fc60ac997fb266da0ab
https://doi.org/10.1016/j.devcel.2018.09.002
https://doi.org/10.1016/j.devcel.2018.09.002