On the Versatility of the sp-, sp2‑, and sp3‑Hybridized Chalcogen-Bearing Molecules To Engage in Type I Chalcogen···Chalcogen Interactions: A Quantum Mechanical Investigation of Like···Like and Unlike Complexes

Autor: Mahmoud A. A. Ibrahim, Rehab R. A. Saeed, Mohammed N. I. Shehata, Nayra A. M. Moussa, Mahmoud E. S. Soliman, Shahzeb Khan, Mohamed A. El-Tayeb, Tamer Shoeib

Publikováno v: ACS Omega, Vol 9, Iss 44, Pp 44448-44456 (2024)

Externí odkaz: https://doaj.org/article/b3cc0eb72d52484f9589d3cb86819d5f

MicroRNA-141-regulated KLK10 and TNFSF-15 gene expression in hepatoblastoma cells as a novel mechanism in liver carcinogenesis

Autor: Ahmed M. Awad, Emad Dabous, Mai Alalem, Nedaa Alalem, Mahmoud E. Nasr, Khaled A. Elawdan, Ghada M. Nasr, Walid Said, Kareem El Khashab, Mohamed S. Basiouny, Adel A. Guirgis, Hany Khalil

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)

Abstract Liver cancer is one of the most pivotal global health problems, leading hepatocellular carcinoma (HCC) with a significant increase in cases worldwide. The role of non-coding-RNA in cancer proliferation and carcinogenesis has attracted much a

Externí odkaz: https://doaj.org/article/7cb56b5e8c324416959b4ad2336706d0

PU-H71 (NSC 750424): a molecular masterpiece that targets HSP90 in cancer and beyond

Autor: Sameh Saber, Rasha Abdelhady, Mai A. Elhemely, Elsayed A. Elmorsy, Rabab S. Hamad, Mustafa Ahmed Abdel-Reheim, Attalla F. El-kott, Mohammed A. AlShehri, Kareem Morsy, Ali S. AlSheri, Mahmoud E. Youssef

Publikováno v: Frontiers in Pharmacology, Vol 15 (2024)

Heat shock protein 90 (HSP90) is a pivotal molecular chaperone with multifaceted roles in cellular health and disease. Herein, we explore how HSP90 orchestrates cellular stress responses, particularly through its partnership with heat shock factor 1

Externí odkaz: https://doaj.org/article/ae750dd3f4a24564bd765d537c78bcf5

Unlocking vinpocetine's oncostatic potential in early-stage hepatocellular carcinoma: A new approach to oncogenic modulation by a nootropic drug.

Autor: Mohammed, Osama A.¹ (AUTHOR), Youssef, Mahmoud E.² (AUTHOR), Hamad, Rabab S.^3,4 (AUTHOR) ahmed_doghish@azhar.edu.eg, Abdel-Reheim, Mustafa Ahmed^5,6 (AUTHOR) rhamad@kfu.edu.sa, Saleh, Lobna A.^7,8 (AUTHOR), Alamri, Mohannad Mohammad S.⁹ (AUTHOR), Alharthi, Muffarah Hamid⁹ (AUTHOR), Alfaifi, Jaber¹⁰ (AUTHOR), Adam, Masoud I. E.¹¹ (AUTHOR), Eleragi, Ali M. S.¹² (AUTHOR), Senbel, Ahmed¹³ (AUTHOR), Farrag, Alshaimaa A.¹⁴ (AUTHOR), Rezigalla, Assad Ali¹⁵ (AUTHOR), El-wakeel, Hend S.^16,17 (AUTHOR), Attia, Mohammed A.^18,19 (AUTHOR), El-Husseiny, Hussein M.^20,21 (AUTHOR), AL-Noshokaty, Tohada M.²² (AUTHOR), Doghish, Ahmed S.^23,24 (AUTHOR) m.ahmed@su.edu.sa, Gaafar, Ahmed Gaafar Ahmed²⁵ (AUTHOR), Saber, Sameh² (AUTHOR)

Publikováno v: PLoS ONE. 10/31/2024, Vol. 19 Issue 10, p1-26. 26p.

The influence of potassium nanoparticles as a foliar fertilizer on onion growth, production, chemical content, and DNA fingerprint

Autor: Dina M. Salama, Mahmoud Ahmed Khater, Mahmoud E. Abd El-Aziz

Publikováno v: Heliyon, Vol 10, Iss 11, Pp e31635- (2024)

Potassium is an important macro-fertilizer for plant growth but can be lost from the soil after application via irrigation. Slow-release nano-fertilizers can achieve sustainable crop cultivation and production, so this study evaluated the influence o

Externí odkaz: https://doaj.org/article/91ae49873c334ee9907fe20d588b176a