Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mahmoud, A E Shahin"'
Autor:
Asmaa A. Mandour, Ibrahim F. Nassar, Mohammed T. Abdel Aal, Mahmoud A. E. Shahin, Wael A. El-Sayed, Maghawry Hegazy, Amr Mohamed Yehia, Ahmed Ismail, Mohamed Hagras, Eslam B. Elkaeed, Hanan M. Refaat, Nasser S. M. Ismail
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1957-1973 (2022)
Cyclin-dependent kinase inhibition is considered a promising target for cancer treatment for its crucial role in cell cycle regulation. Pyrazolo pyrimidine derivatives were well established for their antitumor activity via CDK2 inhibition. In this re
Externí odkaz:
https://doaj.org/article/1e6ab14dd8874e4886ee7d210668ea2f
Autor:
Ibrahim F. Nassar, Mohammed T. Abdel Aal, Wael A. El-Sayed, Mahmoud A. E Shahin, Elsayed G. E. Elsakka, Mahmoud Mohamed Mokhtar, Maghawry Hegazy, Mohamed Hagras, Asmaa A. Mandour, Nasser S. M. Ismail
Publikováno v:
RSC Advances. 12:14865-14882
A new set of pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffolds (4–13) as well as the thioglycoside derivatives (14, 15) were designed, and synthesized as novel CDK2 targeting compounds.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86aedb589d457e6681787883111dcde3
https://doi.org/10.1039/d2ra01968j
https://doi.org/10.1039/d2ra01968j
Autor:
Ibrahim F, Nassar, Mohammed T, Abdel Aal, Wael A, El-Sayed, Mahmoud, A E Shahin, Elsayed G E, Elsakka, Mahmoud Mohamed, Mokhtar, Maghawry, Hegazy, Mohamed, Hagras, Asmaa A, Mandour, Nasser S M, Ismail
Publikováno v:
RSC advances. 12(23)
CDK2 inhibition is an appealing target for cancer treatment that targets tumor cells in a selective manner. A new set of small molecules featuring the privileged pyrazolo[3,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::200c80895d1cf7b677a0bd0e9735705f
https://pubmed.ncbi.nlm.nih.gov/35702208
https://pubmed.ncbi.nlm.nih.gov/35702208