A Rare Noncoding Enhancer Variant in SCN5A Contributes to the High Prevalence of Brugada Syndrome in Thailand.

Autor: Walsh R; Department of Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands. (R.W., I.M., F.M.B., A.O.V., M.K., L.B., C.R.B.).; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, the Netherlands (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., V.M.C., A.A.M.W., C.R.B.).; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.)., Mauleekoonphairoj J; Department of Medicine, Center of Excellence in Arrhythmia Research, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (J.M., W.W., B.S., P.W., N.C., R.C., S.P., K.N., A.K.)., Mengarelli I; Department of Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands. (R.W., I.M., F.M.B., A.O.V., M.K., L.B., C.R.B.).; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, the Netherlands (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., V.M.C., A.A.M.W., C.R.B.).; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.)., Bosada FM; Department of Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands. (R.W., I.M., F.M.B., A.O.V., M.K., L.B., C.R.B.).; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, the Netherlands (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., V.M.C., A.A.M.W., C.R.B.).; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.)., Verkerk AO; Department of Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands. (R.W., I.M., F.M.B., A.O.V., M.K., L.B., C.R.B.).; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands. (A.O.V., K.v.D., V.M.C.).; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, the Netherlands (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., V.M.C., A.A.M.W., C.R.B.).; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.)., van Duijvenboden K; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands. (A.O.V., K.v.D., V.M.C.)., Poovorawan Y; Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (Y.P., A.K.)., Wongcharoen W; Department of Medicine, Center of Excellence in Arrhythmia Research, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (J.M., W.W., B.S., P.W., N.C., R.C., S.P., K.N., A.K.)., Sutjaporn B; Department of Medicine, Center of Excellence in Arrhythmia Research, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (J.M., W.W., B.S., P.W., N.C., R.C., S.P., K.N., A.K.)., Wandee P; Department of Medicine, Center of Excellence in Arrhythmia Research, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (J.M., W.W., B.S., P.W., N.C., R.C., S.P., K.N., A.K.)., Chimparlee N; Department of Medicine, Center of Excellence in Arrhythmia Research, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (J.M., W.W., B.S., P.W., N.C., R.C., S.P., K.N., A.K.).; Department of Medicine, Piyavate Hospital, Bangkok, Thailand (N.C.)., Chokesuwattanaskul R; Department of Medicine, Center of Excellence in Arrhythmia Research, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (J.M., W.W., B.S., P.W., N.C., R.C., S.P., K.N., A.K.)., Vongpaisarnsin K; Department of Forensic Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (K.V.).; Department of Center of Excellence in Forensic Genetics, Ratchadapiseksompotch Fund, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (K.V., P.D.)., Dangkao P; Department of Center of Excellence in Forensic Genetics, Ratchadapiseksompotch Fund, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (K.V., P.D.).; Forensic Serology and DNA, King Chulalongkorn Memorial Hospital and Thai Red Cross Society, Bangkok, Thailand (P.D.)., Wu CI; Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taiwan (C.-I.W.)., Tadros R; Department of Medicine, Cardiovascular Genetics Center, Montreal Heart Institute and Faculty of Medicine, Université de Montréal, Quebec, Canada (R.T.)., Amin AS; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, the Netherlands (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., V.M.C., A.A.M.W., C.R.B.).; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.).; Department of Clinical Cardiology, Heart Centre, Amsterdam University Medical Centre, location AMC, the Netherlands (A.S.A., K.V.V.L., P.G.P., A.A.M.W.)., Lieve KVV; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, the Netherlands (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., V.M.C., A.A.M.W., C.R.B.).; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.).; Department of Clinical Cardiology, Heart Centre, Amsterdam University Medical Centre, location AMC, the Netherlands (A.S.A., K.V.V.L., P.G.P., A.A.M.W.)., Postema PG; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, the Netherlands (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., V.M.C., A.A.M.W., C.R.B.).; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.).; Department of Clinical Cardiology, Heart Centre, Amsterdam University Medical Centre, location AMC, the Netherlands (A.S.A., K.V.V.L., P.G.P., A.A.M.W.)., Kooyman M; Department of Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands. (R.W., I.M., F.M.B., A.O.V., M.K., L.B., C.R.B.).; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, the Netherlands (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., V.M.C., A.A.M.W., C.R.B.).; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.)., Beekman L; Department of Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands. (R.W., I.M., F.M.B., A.O.V., M.K., L.B., C.R.B.).; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, the Netherlands (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., V.M.C., A.A.M.W., C.R.B.).; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.)., Sahasatas D; Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand (D.S., P.M.)., Amnueypol M; Department of Medicine, Faculty of Medicine at Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. (M.A., T. Ngarmukos)., Krittayaphong R; Department of Faculty of Medicine at Siriraj Hospital, Mahidol University, Bangkok, Thailand. (R.K.)., Prechawat S; Department of Medicine, Center of Excellence in Arrhythmia Research, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (J.M., W.W., B.S., P.W., N.C., R.C., S.P., K.N., A.K.)., Anannab A; Department of Cardiovascular and Intervention, Central Chest Institute of Thailand, Nonthaburi, Thailand (A.A.)., Makarawate P; Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand (D.S., P.M.)., Ngarmukos T; Department of Medicine, Faculty of Medicine at Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. (M.A., T. Ngarmukos)., Phusanti K; Department of Medicine, Maharat Nakhon Ratchasima Hospital, Nakorn Ratchasima, Thailand (K.P.)., Veerakul G; Bangkok Heart Hospital, Bangkok General Hospital, Thailand (G.V., A.K.)., Kingsbury Z; Illumina Cambridge Ltd, Granta Park, Great Abington, Cambridge, UK (Z.K., T. Newington, U.M., M.T.R.)., Newington T; Illumina Cambridge Ltd, Granta Park, Great Abington, Cambridge, UK (Z.K., T. Newington, U.M., M.T.R.)., Maheswari U; Illumina Cambridge Ltd, Granta Park, Great Abington, Cambridge, UK (Z.K., T. Newington, U.M., M.T.R.)., Ross MT; Illumina Cambridge Ltd, Granta Park, Great Abington, Cambridge, UK (Z.K., T. Newington, U.M., M.T.R.)., Grace A; Department of Biochemistry, University of Cambridge, UK (A.G.)., Lambiase PD; Cardiology, Medicine, Barts Heart Centre, London, UK (P.D.L.).; Institute of Cardiovascular Science, Population Health, UCL, London, UK (P.D.L.)., Behr ER; Molecular and Clinical Sciences Research Institute, St. George's, University of London, UK (E.R.B.).; Cardiology Clinical Academic Group, St. George's University Hospitals NHS Foundation Trust, London, UK (E.R.B.)., Schott JJ; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.).; Nantes Université, CHU Nantes, CNRS, INSERM, l'Institut du Thorax, Nantes, France (J.-J.S., R.R., J.B.)., Redon R; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.).; Nantes Université, CHU Nantes, CNRS, INSERM, l'Institut du Thorax, Nantes, France (J.-J.S., R.R., J.B.)., Barc J; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.).; Nantes Université, CHU Nantes, CNRS, INSERM, l'Institut du Thorax, Nantes, France (J.-J.S., R.R., J.B.)., Christoffels VM; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands. (A.O.V., K.v.D., V.M.C.).; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, the Netherlands (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., V.M.C., A.A.M.W., C.R.B.)., Wilde AAM; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, the Netherlands (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., V.M.C., A.A.M.W., C.R.B.).; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.).; Department of Clinical Cardiology, Heart Centre, Amsterdam University Medical Centre, location AMC, the Netherlands (A.S.A., K.V.V.L., P.G.P., A.A.M.W.)., Nademanee K; Department of Medicine, Center of Excellence in Arrhythmia Research, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (J.M., W.W., B.S., P.W., N.C., R.C., S.P., K.N., A.K.).; Pacific Rim Electrophysiology Research Institute, Bumrungrad Hospital, Bangkok, Thailand (K.N.)., Bezzina CR; Department of Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands. (R.W., I.M., F.M.B., A.O.V., M.K., L.B., C.R.B.).; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, the Netherlands (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., V.M.C., A.A.M.W., C.R.B.).; Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (R.W., I.M., F.M.B., A.O.V., A.S.A., K.V.V.L., P.G.P., M.K., L.B., J.-J.S., R.R., J.B., A.A.M.W., C.R.B.)., Khongphatthanayothin A; Department of Medicine, Center of Excellence in Arrhythmia Research, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (J.M., W.W., B.S., P.W., N.C., R.C., S.P., K.N., A.K.).; Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. (Y.P., A.K.).; Bangkok Heart Hospital, Bangkok General Hospital, Thailand (G.V., A.K.).

Publikováno v: Circulation [Circulation] 2024 Oct 11. Date of Electronic Publication: 2024 Oct 11.

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Effect of Prosthetic Rehabilitation on Airway Space in Edentulous Patients with Obstructive Sleep Apnea- a Preliminary Observational Study.

Autor: Krishnamurthy P; Past- Postgraduate, Dept. of Prosthodontics and Crown & Bridge, Sri Ramchandra Institute of Higher Education and Research, Sriher, India., Maheswari U; Dept. of Prosthodontics and Crown & Bridge, Sri Ramchandra Institute of Higher Education & Research, Sriher, India., Mohamed K; Dept. of Prosthodontics and Crown & Bridge, Sri Ramchandra Institute of Higher Education & Research, Sriher, India.

Publikováno v: Journal of dentistry (Shiraz, Iran) [J Dent (Shiraz)] 2023 Dec 01; Vol. 24 (4), pp. 382-388. Date of Electronic Publication: 2023 Dec 01 (Print Publication: 2023).

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Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features.

Autor: Robbe P; Department of Oncology, University of Oxford, Oxford, UK.; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Ridout KE; Department of Oncology, University of Oxford, Oxford, UK., Vavoulis DV; Department of Oncology, University of Oxford, Oxford, UK., Dréau H; Department of Oncology, University of Oxford, Oxford, UK., Kinnersley B; Division of Genetics and Epidemiology, The Institute of Cancer Research, Sutton, UK., Denny N; Department of Medicine, Medical Research Council Molecular Haematology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Chubb D; Division of Genetics and Epidemiology, The Institute of Cancer Research, Sutton, UK., Appleby N; Department of Oncology, University of Oxford, Oxford, UK., Cutts A; Department of Oncology, University of Oxford, Oxford, UK., Cornish AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, Sutton, UK., Lopez-Pascua L; UK Health Security Agency, London, UK., Clifford R; Department of Haematology, University Hospital Limerick, Limerick, Ireland.; Limerick Digital Cancer Research Centre, School of Medicine,University of Limerick, Limerick, Ireland., Burns A; Department of Oncology, University of Oxford, Oxford, UK., Stamatopoulos B; Laboratory of Clinical Cell Therapy, Jules Bordet Institute, ULB Cancer Research Center (U-CRC)- Université Libre de Bruxelles (ULB), Brussels, Belgium., Cabes M; Oxford Molecular Diagnostics Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, UK., Alsolami R; Department of Medical Laboratory Technology, King Abdulaziz University, Jeddah, Saudi Arabia., Antoniou P; Illumina Cambridge Ltd., Cambridge, UK., Oates M; University of Liverpool, Liverpool, UK., Cavalieri D; Department of Haematology, CHU de Clermont-Ferrand, Clermont-Ferrand, France., Gibson J; Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Prabhu AV; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Schwessinger R; Department of Medicine, Medical Research Council Molecular Haematology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Jennings D; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., James T; Illumina Cambridge Ltd., Cambridge, UK., Maheswari U; Illumina Cambridge Ltd., Cambridge, UK., Duran-Ferrer M; Biomedical Epigenomics Group, Institut d'Investigacions Biomédiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain., Carninci P; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Human Technopole, Milan, Italy., Knight SJL; Oxford University Clinical Academic Graduate School, University of Oxford Medical Sciences Division, University of Oxford, John Radcliffe Hospital, Oxford, UK., Månsson R; Center for Hematology and Regenerative Medicine Huddinge, Karolinska Institute, Stockholm, Sweden., Hughes J; Department of Medicine, Medical Research Council Molecular Haematology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Davies J; Department of Medicine, Medical Research Council Molecular Haematology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Ross M; Illumina Cambridge Ltd., Cambridge, UK., Bentley D; Illumina Cambridge Ltd., Cambridge, UK., Strefford JC; Cancer Genomics, Cancer Sciences, Faculty of Medicine, Group University of Southampton, Southampton, UK., Devereux S; King's College Hospital, NHS Foundation Trust, London, UK.; Kings College London, London, UK., Pettitt AR; Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK.; Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, UK., Hillmen P; St James's University Hospital, Leeds, UK., Caulfield MJ; Genomics England, London, UK.; William Harvey Research Institute, Queen Mary University of London, London, UK., Houlston RS; Division of Genetics and Epidemiology, The Institute of Cancer Research, Sutton, UK., Martín-Subero JI; Human Technopole, Milan, Italy.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Schuh A; Department of Oncology, University of Oxford, Oxford, UK. anna.schuh@oncology.ox.ac.uk.

Publikováno v: Nature genetics [Nat Genet] 2022 Nov; Vol. 54 (11), pp. 1675-1689. Date of Electronic Publication: 2022 Nov 04.