Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Maheshwor Thapa"'
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 6, p e1011912 (2024)
To standardize metabolomics data analysis and facilitate future computational developments, it is essential to have a set of well-defined templates for common data structures. Here we describe a collection of data structures involved in metabolomics
Externí odkaz:
https://doaj.org/article/9e39222fa6d9460a9f0042e59533afb4
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Significant challenges remain in the computational processing of data from liquid chomratography-mass spectrometry (LC-MS)-based metabolomic experiments into metabolite features. In this study, we examine the issues of provenance and reprodu
Externí odkaz:
https://doaj.org/article/f08e458eba1f42cf875218d8f3bffea5
Autor:
Amnah Siddiqa, Yating Wang, Maheshwor Thapa, Dominique E. Martin, Andreia N. Cadar, Jenna M. Bartley, Shuzhao Li
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract Many human diseases, including metabolic diseases, are intertwined with the immune system. The understanding of how the human immune system interacts with pharmaceutical drugs is still limited, and epidemiological studies only start to emerg
Externí odkaz:
https://doaj.org/article/b31f90f504ed4b32862f88657fc4bb1a
Autor:
Daniela D. Weber, Sepideh Aminzadeh-Gohari, Maheshwor Thapa, Anna-Sophia Redtenbacher, Luca Catalano, Tânia Capelôa, Thibaut Vazeille, Michael Emberger, Thomas K. Felder, René G. Feichtinger, Peter Koelblinger, Guido Dallmann, Pierre Sonveaux, Roland Lang, Barbara Kofler
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-20 (2022)
Abstract Background Growing evidence supports the use of low-carbohydrate/high-fat ketogenic diets as an adjunctive cancer therapy. However, it is unclear which genetic, metabolic, or immunological factors contribute to the beneficial effect of ketog
Externí odkaz:
https://doaj.org/article/2d1d742289f44a19bbc1d95c27545516
Significant challenges still exist in the computational processing of data from LC-MS metabolomic experiments into metabolite features. In this study, we examine the issues of provenance and reproducibility in the current software tools. The inconsis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::780eb6606e947a0cd6c87e364dd94a70
https://doi.org/10.1101/2022.06.10.495665
https://doi.org/10.1101/2022.06.10.495665
Autor:
Arti Taggar, Maheshwor Thapa, Minghao Gong, Anahita Amiri, Daniel R. Grow, Shuzhao Li, Paul Robson
Publikováno v:
Fertility and Sterility. 118:e340
Autor:
Michael Emberger, Sepideh Aminzadeh-Gohari, Guido Dallmann, Maheshwor Thapa, Peter Koelblinger, René G. Feichtinger, Daniela D. Weber, Barbara Kofler, Anna-Sophia Redtenbacher, Luca Catalano, Roland Lang
Publikováno v:
Cancers, Vol 13, Iss 434, p 434 (2021)
Cancers
Volume 13
Issue 3
Cancers
Volume 13
Issue 3
Simple Summary Studying the metabolome, the complete set of metabolites found in a biological sample, helps to understand how metabolism differs between healthy and diseased individuals. Malignant skin cancers (melanomas) differ greatly in their muta
Autor:
Maheshwor Thapa, Hye-Ran Yoon
Publikováno v:
Yakhak Hoeji. 62:7-13
A rapid and simple screening method was developed for the simultaneous analysis of 6 sulfur-containing amino acids from human plasma at ng level. The...
Publikováno v:
Analytical Science and Technology. 28:323-330
Alkaptonuria, a rare inherited metabolic disease, is characterized by a lack of homogentisate dioxygenase and accumulation of homogentisic acid (HGA), leading to homogentisic aciduria, arthritis, and ochronosis. In this study, a rapid analytical meth
Autor:
Guido Dallmann, Maheshwor Thapa
Publikováno v:
Seminars in Cell & Developmental Biology
Cancer is a heterogeneous set of diseases characterized by the rewiring of cellular signaling and the reprogramming of metabolic pathways to sustain growth and proliferation. In past decades, studies were focused primarily on the genetic complexity o