Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Maheshi N Ramasamy"'
Publikováno v:
Expert Review of Vaccines, Vol 22, Iss 1, Pp 918-920 (2023)
Externí odkaz:
https://doaj.org/article/1386ecafdb96449abfd765cb9907964b
Autor:
Melanie Greenland, Elizabeth Jones, Xinxue Liu, Andrew J Pollard, Brian Angus, Susana Camara, Hannah Robinson, Marije Verheul, Jennifer Hill, Myron M Levine, Katherine Emary, Nisha Singh, Naina McCann, Florence Mclean, Young Chan Kim, Kerry Conlin, Maheshi N Ramasamy
Publikováno v:
BMJ Open, Vol 13, Iss 5 (2023)
Introduction This is the first efficacy study of an oral live attenuated vaccine against Salmonella Paratyphi A using a human challenge model of paratyphoid infection. S. Paratyphi A is responsible for 3.3 million cases of enteric fever every year, w
Externí odkaz:
https://doaj.org/article/4888324a7417428cb6b3d8a9b2e9826b
Autor:
Sue Ann Costa Clemens, Pedro M. Folegatti, Katherine R. W. Emary, Lily Yin Weckx, Jeremy Ratcliff, Sagida Bibi, Ana Verena De Almeida Mendes, Eveline Pipolo Milan, Ana Pittella, Alexandre V. Schwarzbold, Eduardo Sprinz, Parvinder K. Aley, David Bonsall, Christophe Fraser, Michelle Fuskova, Sarah C. Gilbert, Daniel Jenkin, Sarah Kelly, Simon Kerridge, Teresa Lambe, Natalie G. Marchevsky, Yama F. Mujadidi, Emma Plested, Maheshi N. Ramasamy, Peter Simmonds, Tanya Golubchik, Merryn Voysey, Andrew J. Pollard, the AMPHEUS Project, Oxford COVID Vaccine Trial Team
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Emerging variants of SARS-CoV-2 raise concerns about vaccine efficiency. Here, the authors present a post-hoc analysis for the ChAdOx1 nCoV-19 (AZD1222) vaccine trial in Brazil and provide efficacy against symptomatic COVID-19 caused by the Zeta (P.2
Externí odkaz:
https://doaj.org/article/2174b542d59f4531bfbfd908fa719572
Autor:
Sarah Fidler, Julie Fox, Timothy Tipoe, Stephanie Longet, Tom Tipton, Movin Abeywickrema, Sandra Adele, Jasmini Alagaratnam, Mohammad Ali, Parvinder K Aley, Suhail Aslam, Anbhu Balasubramanian, Anna Bara, Tanveer Bawa, Anthony Brown, Helen Brown, Federica Cappuccini, Sophie Davies, Jamie Fowler, Leila Godfrey, Anna L Goodman, Kathrine Hilario, Carl-Philipp Hackstein, Moncy Mathew, Yama F Mujadidi, Alice Packham, Claire Petersen, Emma Plested, Katrina M Pollock, Maheshi N Ramasamy, Hannah Robinson, Nicola Robinson, Patpong Rongkard, Helen Sanders, Teona Serafimova, Niamh Spence, Anele Waters, Danielle Woods, Panagiota Zacharopoulou, Eleanor Barnes, Susanna Dunachie, Philip Goulder, Paul Klenerman, Alan Winston, Adrian V S Hill, Sarah C Gilbert, Miles Carroll, Andrew J Pollard, Teresa Lambe, Ane Ogbe, John Frater
Publikováno v:
Clinical Infectious Diseases. 76:201-209
Background People with human immunodeficiency virus (HIV) on antiretroviral therapy (ART) with good CD4 T-cell counts make effective immune responses following vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). There ar
Autor:
Robert H. Shaw, Melanie Greenland, Arabella S.V. Stuart, Parvinder K. Aley, Nick J. Andrews, J. Claire Cameron, Sue Charlton, Elizabeth A. Clutterbuck, Andrea M. Collins, Tom Darton, Tanya Dinesh, Christopher J.A. Duncan, Saul N. Faust, Daniela M. Ferreira, Adam Finn, Anna L. Goodman, Christopher A. Green, Bassam Hallis, Paul T. Heath, Helen Hill, Teresa Lambe, Vincenzo Libri, Patrick J. Lillie, Ella Morey, Yama F. Mujadidi, Ruth Payne, Emma L. Plested, Samuel Provstgaard-Morys, Maheshi N. Ramasamy, Mary Ramsay, Robert C. Read, Hannah Robinson, Gavin R. Screaton, Nisha Singh, David P.J. Turner, Paul J. Turner, Rachel White, Jonathan S. Nguyen-Van-Tam, Xinxue Liu, Matthew D. Snape
Background: Heterologous COVID vaccine priming schedules are immunogenic and effective. This report aims to understand the persistence of immune response to the viral vectored, mRNA and protein-based COVID-19 vaccine platforms used in homologous and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8c3e1d3669d237889b08bc9c1ae99e
http://hdl.handle.net/10044/1/103718
http://hdl.handle.net/10044/1/103718
Autor:
Merryn Voysey, Amy Flaxman, Jeremy Aboagye, Parvinder K Aley, Sandra Belij-Rammerstorfer, Sagida Bibi, Mustapha Bittaye, Federica Cappuccini, Sue Charlton, Elizabeth A Clutterbuck, Sophie Davies, Christina Dold, Nick J Edwards, Katie J Ewer, Saul N Faust, Pedro M Folegatti, Jamie Fowler, Ciaran Gilbride, Sarah C Gilbert, Leila Godfrey, Bassam Hallis, Holly E Humphries, Daniel Jenkin, Simon Kerridge, Yama F Mujadidi, Emma Plested, Maheshi N Ramasamy, Hannah Robinson, Helen Sanders, Matthew D Snape, Rinn Song, Kelly M Thomas, Marta Ulaszewska, Danielle Woods, Daniel Wright, Andrew J Pollard, Teresa Lambe
The trajectory of immune responses following the primary dose series determines the decline in vaccine effectiveness over time. Here we report on maintenance of immune responses during the year following a two-dose schedule of ChAdOx1 nCoV-19/AZD1222
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca008dfeea2ae68ee3c352ef24ca2bb
https://doi.org/10.1093/cei/uxad013
https://doi.org/10.1093/cei/uxad013
Autor:
Robert H Shaw, Xinxue Liu, Arabella S V Stuart, Melanie Greenland, Parvinder K Aley, Nick J Andrews, J Claire Cameron, Sue Charlton, Elizabeth A Clutterbuck, Andrea M Collins, Wanwisa Dejnirattisai, Tanya Dinesh, Saul N Faust, Daniela M Ferreira, Adam Finn, Christopher A Green, Bassam Hallis, Paul T Heath, Helen Hill, Teresa Lambe, Rajeka Lazarus, Vincenzo Libri, Fei Long, Yama F Mujadidi, Emma L Plested, Ella R Morey, Samuel Provstgaard-Morys, Maheshi N Ramasamy, Mary Ramsay, Robert C Read, Hannah Robinson, Gavin R Screaton, Nisha Singh, David P J Turner, Paul J Turner, Iason Vichos, Laura L Walker, Rachel White, Jonathan S Nguyen-Van-Tam, Matthew D Snape, Alasdair P.S. Munro, Jazz Bartholomew, Laura Presland, Sarah Horswill, Sarah Warren, Sophie Varkonyi-Clifford, Stephen Saich, Kirsty Adams, Marivic Ricamara, Nicola Turner, Nicole Y. Yee Ting, Sarah Whittley, Tommy Rampling, Amisha Desai, Claire H. Brown, Ehsaan Qureshi, Karishma Gokani, Kush Naker, Johanna K. Kellett Wright, Rachel L. Williams, Tawassal Riaz, Florentina D. Penciu, Amy Carson, Claudio Di Maso, Gracie Mead, Elizabeth G. Howe, Mujtaba Ghulam Farooq, Rabiullah Noristani, Xin L. Yao, Neil J. Oldfield, Daniel Hammersley, Sue Belton, Simon Royal, Alberto San Francisco Ramos, Cecilia Hultin, Eva P. Galiza, Rebecca Crook, Marcin Bula, Fred Fyles, Hassan Burhan, Flora Maelin, Elen Hughes, Emmanuel Okenyi
Publikováno v:
Shaw, R H, Liu, X, Stuart, A S V, Greenland, M, Aley, P K, Andrews, N J, Finn, A & Lazarus, R & et, A 2022, ' Effect of priming interval on reactogenicity, peak immunological response, and waning after homologous and heterologous COVID-19 vaccine schedules : exploratory analyses of Com-COV, a randomised control trial ', Lancet Respiratory Medicine, vol. 10, no. 11, pp. 1049-1060 . https://doi.org/10.1016/S2213-2600(22)00163-1
Background Priming COVID-19 vaccine schedules have been deployed at variable intervals globally, which might influence immune persistence and the relative importance of third-dose booster programmes. Here, we report exploratory analyses from the Com-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed4ea510bf1be44fbc2afbfb9cf0590
https://eprints.soton.ac.uk/456454/
https://eprints.soton.ac.uk/456454/
Autor:
Naina McCann, Katherine Emary, Nisha Singh, Florence Mclean, Susana Camara, Elizabeth Jones, Young Chan Kim, Xinxue Liu, Melanie Greenland, Kerry Conlin, Jennifer Hill, Marije Verheul, Hannah Robinson, Brian Angus, Maheshi N Ramasamy, Myron M Levine, Andrew J Pollard
Publikováno v:
BMJ Open. 13:e068966
IntroductionThis is the first efficacy study of an oral live attenuated vaccine againstSalmonellaParatyphi A using a human challenge model of paratyphoid infection.S. Paratyphi A is responsible for 3.3 million cases of enteric fever every year, with
Autor:
Christian S Marchello, Megan Birkhold, John A Crump, Laura B. Martin, Michael O. Ansah, Gianluca Breghi, Rocio Canals, Fabio Fiorino, Melita A. Gordon, Jong-Hoon Kim, Mainga Hamaluba, Brama Hanumunthadu, Jan Jacobs, Samuel Kariuki, Stefano Malvolti, Carsten Mantel, Florian Marks, Donata Medaglini, Vittal Mogasale, Chisomo L. Msefula, Esther Muthumbi, Tonney S. Niyrenda, Robert Onsare, Ellis Owusu-Dabo, Elena Pettini, Maheshi N. Ramasamy, Bassiahi A. Soura, Tiziana Spadafina, Bieke Tack
Publikováno v:
The Lancet Infectious Diseases
BACKGROUND: Non-typhoidal salmonella can cause serious, life-threatening invasive infections involving the bloodstream and other normally sterile sites. We aimed to systematically review the prevalence of complications and case-fatality ratio (CFR) o
Autor:
Amy Flaxman, Natalie Marchevsky, Daniel Jenkin, Jeremy Aboagye, Parvinder K. Aley, Brian John Angus, Sandra Belij-Rammerstorfer, Sagida Bibi, Mustapha Bittaye, Federica Cappuccini, Paola Cicconi, Elizabeth Clutterbuck, Sophie Davies, Wanwisa Dejnirattisai, Christina Dold, Katie Ewer, Pedro M. Folegatti, Jamie Fowler, Adrian V. S. Hill, Simon Kerridge, Angela M. Minassian, Juthathip Mongkolspaya, Yama Farooq Mujadidi, Emma Plested, Maheshi N. Ramasamy, Hannah Robinson, Helen Sanders, Emma Sheehan, Holly Smith, Matthew D. Snape, Rinn Song, Danielle Woods, Gavin R. Screaton, Sarah C. Gilbert, Merryn Voysey, Andrew Pollard, Teresa Lambe, The Oxford COVID Vaccine Group
Publikováno v:
SSRN Electronic Journal.
Background: COVID-19 vaccine supply shortages are causing concerns about compromised immunity in some countries as the interval between first and second dose extends. Conversely, countries with no supply constraints are considering administering a th