Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mahesha Gangadhariah"'
Autor:
Shashi Shekhar Singh, Avinash Kumar, Nicole Welch, Jinendiran Sekar, Saurabh Mishra, Annette Bellar, Mahesha Gangadhariah, Amy Attaway, Hayder Al Khafaji, Xiaoqin Wu, Vai Pathak, Vandana Agrawal, Megan R. McMullen, Troy A. Hornberger, Laura E. Nagy, Gangarao Davuluri, Srinivasan Dasarathy
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss 1, Pp 91-116 (2021)
Externí odkaz:
https://doaj.org/article/149adb9bba314f0284ac3b35b53225aa
Autor:
Ambra Pozzi, Jorge H. Capdevila, Roy Zent, Jawahar Lal Jat, John R. Falck, Shouzuo Wei, Mahesha Gangadhariah, Shilin Yang, Stacey Mont, Yan Su, Wen Hu, Xiwu Chen, Nataliya Skrypnyk
PDF file - 68K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f303a30d8a413425d64342157b34c2f
https://doi.org/10.1158/0008-5472.22402593.v1
https://doi.org/10.1158/0008-5472.22402593.v1
Autor:
Ambra Pozzi, Jorge H. Capdevila, Roy Zent, Jawahar Lal Jat, John R. Falck, Shouzuo Wei, Mahesha Gangadhariah, Shilin Yang, Stacey Mont, Yan Su, Wen Hu, Xiwu Chen, Nataliya Skrypnyk
PDF file - 24K, Analysis of p60.5 and KrasLA2 tumor cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486024e2d3eeddba2b9278b139130444
https://doi.org/10.1158/0008-5472.22402602.v1
https://doi.org/10.1158/0008-5472.22402602.v1
Autor:
Mahesha Gangadhariah, Triveni Pardhi, Jahnavi Ravilla, Subhash Chandra, Sridevi Annapurna Singh
Publikováno v:
Journal of biomolecular structuredynamics.
Peroxisome proliferator-activated receptor gamma (PPARγ) agonists are potent insulin sensitizers in treating type 2 diabetes. Despite being very effective in the fight against diabetes-mediated complications, PPARγ agonists are accompanied by sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76fea7eda0088299ae5028e008363e63
https://pubmed.ncbi.nlm.nih.gov/36576222
https://pubmed.ncbi.nlm.nih.gov/36576222
Autor:
Gangarao Davuluri, Maradumane L. Mohan, George R. Stark, Rebecca L. McCullough, Samjhana Thapaliya, Srinivasan Dasarathy, Laura E. Nagy, Megan R. McMullen, Sathyamangla V. Naga Prasad, Jinendiran Sekar, Mahesha Gangadhariah, Nicole Welch, McKenzie Stine, Sashi Kant, Avinash Kumar, Khaled Alsabbagh Alchirazi
Publikováno v:
Hepatology
BACKGROUND AND AIMS Despite the high clinical significance of sarcopenia in alcohol-associated cirrhosis, there are currently no effective therapies because the underlying mechanisms are poorly understood. We determined the mechanisms of ethanol-indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d92af699109255e881bd8cb3be6c64
https://doi.org/10.1002/hep.31524
https://doi.org/10.1002/hep.31524
Autor:
Megan R. McMullen, Mahesha Gangadhariah, Srinivasan Dasarathy, Troy A. Hornberger, Saurabh Mishra, Gangarao Davuluri, Hayder Al Khafaji, Avinash Kumar, Annette Bellar, Laura E. Nagy, Xiaoqin Wu, Amy Attaway, Nicole Welch, Vandana Agrawal, Shashi Shekhar Singh, Vai Pathak, Jinendiran Sekar
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss 1, Pp 91-116 (2021)
BACKGROUND/AIMS: Signaling and metabolic perturbations contribute to dysregulated skeletal muscle protein homeostasis and secondary sarcopenia in response to a number of cellular stressors including ethanol exposure. Using an innovative multiomics-ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a5c2cba31563cdc4c283276b4c09cf
https://www.cellphysiolbiochem.com/Articles/000327/
https://www.cellphysiolbiochem.com/Articles/000327/
Autor:
Mahesha Gangadhariah, Megan R. McMullen, Avinash Kumar, Gangarao Davuluri, Anupama Priyadarshini, Laura E. Nagy, Charles L. Hoppel, Nicole Welch, Belinda Willard, Srinivasan Dasarathy, Adam Kim, Yana Sandlers, Allawy Allawy
Publikováno v:
Free Radic Biol Med
Protein synthesis and autophagy are regulated by cellular ATP content. We tested the hypothesis that mitochondrial dysfunction, including generation of reactive oxygen species (ROS), contributes to impaired protein synthesis and increased proteolysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95773dcb796f6195360bbb39f724abea
https://doi.org/10.1016/j.freeradbiomed.2019.09.031
https://doi.org/10.1016/j.freeradbiomed.2019.09.031
Autor:
Roy Zent, Mahesha Gangadhariah, James M. Luther, Megan M Shuey, Shaojun Mei, F. Peter Guengerich, Lindsay N. Sausville, Manuel Chiusa, J. Capdevila, Ambra Pozzi, Scott M. Williams, Shouzuo Wei, John R. Falck
Publikováno v:
Cancer Research. 78:4865-4877
Increased expression of cytochrome P450 CYP2C9, together with elevated levels of its products epoxyeicosatrienoic acids (EET), is associated with aggressiveness in cancer. Cytochrome P450 variants CYP2C9*2 and CYP2C9*3 encode proteins with reduced en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f2d5f68adeea617b675dcd6adf17da
https://doi.org/10.1158/0008-5472.can-17-3977
https://doi.org/10.1158/0008-5472.can-17-3977
Autor:
Srinivasan Dasarathy, Joseph A. DiDonato, Oliver Wessely, Adam Kim, Belinda Willard, Khaled Alsabbagh, Karyn A. Esser, Anthony J. DiDonato, Gangarao Davuluri, Mahesha Gangadhariah, Daniel M Krajcik, Satdarshan P.S. Monga, Michela Giusto, Paul L. Fox, George R. Stark, Nicole Welch, Avinash Kumar, Rajeev Chandel, Uyen Tran, Kommireddy Vasu, Prabar K. Ghosh, Sashi Kant, Yuxin Wang
Publikováno v:
Molecular and cellular biology. 39(16)
Increased ribosomal biogenesis occurs during tissue hypertrophy, but whether ribosomal biogenesis is impaired during atrophy is not known. We show that hyperammonemia, which occurs in diverse chronic disorders, impairs protein synthesis as a result o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7cc027a8a0c56f2d31072f2fad5ab4
https://pubmed.ncbi.nlm.nih.gov/31138664
https://pubmed.ncbi.nlm.nih.gov/31138664
Autor:
David Weiner, Claire Heit, Anna Maria Marini, Adam Kim, Nicole Welch, Gangarao Davuluri, Khaled Ka Alchirazi, Donal Ds Luse, Mahesha Gangadhariah, Sashi Kant, Srinivasan Dasarathy, Belinda Willard, Avinash Kumar, Laura E. Nagy, Vasilis Vasiliou, Megan Mr McMullen
Publikováno v:
J Biol Chem
The Journal of biological chemistry
The Journal of biological chemistry
Ethanol causes dysregulated muscle protein homeostasis while simultaneously causing hepatocyte injury. Since hepatocytes are the primary site for physiological disposal of ammonia, a cytotoxic cellular metabolite generated during a number of metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e058bf738300d9a1e7d799188e375ed
https://pubmed.ncbi.nlm.nih.gov/30872403
https://pubmed.ncbi.nlm.nih.gov/30872403