Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mahesh de Alwis"'
Autor:
James W B Bainbridge, G.–M. Sarra, Alexander J. Smith, Mahesh de Alwis, Robin R. Ali, C Stephens, Adrian J. Thrasher
Publikováno v:
Human Molecular Genetics. 10:2353-2361
The retinal degeneration slow (rds or Prph2(Rd2/Rd2)) mouse, a model of recessive retinitis pigmentosa, lacks a functional gene encoding peripherin 2. This membrane glycoprotein is required for the formation of photoreceptor outer segment discs. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1b74ed9a0b805cff924c7facc5005e
https://doi.org/10.1093/hmg/10.21.2353
https://doi.org/10.1093/hmg/10.21.2353
Autor:
Stuart A. Nicklin, Andrew H. Baker, Hildegard Buening, Anne Girod, Michael Hallek, Uli Hacker, Adrian J. Thrasher, Mahesh de Alwis, Kate L. Dishart, Robin R. Ali
Publikováno v:
Molecular Therapy. 4:174-181
Gene therapy vectors based on adeno-associated virus-2 (AAV2) offer considerable promise for human gene therapy. Applications for AAV vectors are limited to tissues efficiently transduced by the vector due to its natural tropism, which is predominant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9b97f2322355954d79b54caa037362
https://doi.org/10.1006/mthe.2001.0424
https://doi.org/10.1006/mthe.2001.0424
Publikováno v:
Journal of Virological Methods. 96:97-105
A major limitation of adeno-associated virus (AAV) based vectors for clinical applications to date is the production of high-titer recombinant AAV vector stocks. Despite recent improvements, the amount of recombinant adeno-associated virus vectors (r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::562070495975f3bcd54b3515db0028ed
https://doi.org/10.1016/s0166-0934(01)00298-1
https://doi.org/10.1016/s0166-0934(01)00298-1
Autor:
MB Reichel, G.–M. Sarra, Mahesh de Alwis, Sascha Fauser, Peter M. G. Munro, Adrian J. Thrasher, James W B Bainbridge, Shomi S. Bhattacharya, Christine Kinnon, Robin R. Ali, C Stephens, David M. Hunt
Publikováno v:
Nature Genetics. 25:306-310
The gene Prph2 encodes a photoreceptor-specific membrane glycoprotein1, peripherin-2 (also known as peripherin/rds), which is inserted into the rims of photoreceptor outer segment discs in a complex with rom-1 (ref. 2). The complex is necessary for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f75090e4c4c80dccecf7a797a594f8
https://doi.org/10.1038/77068
https://doi.org/10.1038/77068
Autor:
Alison Jones, Christine Kinnon, Ruth C. Lovering, Sally Genet, Mahesh de Alwis, Helen Middleton-Price, Sue Malcolm, Gareth Morgan, Roland J. Levinsky, Lesley A. Alterman
Publikováno v:
Journal of Immunological Methods. 166:111-116
We report the development of a relatively quick and simple method for the assessment of X inactivation status for carrier determination in families affected by X-linked agammaglobulinemia (XLA). This method utilises an immunomagnetic separation techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a81425c6835c2b63b7929f9b221aff
https://doi.org/10.1016/0022-1759(93)90334-4
https://doi.org/10.1016/0022-1759(93)90334-4
Publikováno v:
Methods in molecular medicine. 69
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad53958ca2fdd652c1c227420d91826e
https://pubmed.ncbi.nlm.nih.gov/11987794
https://pubmed.ncbi.nlm.nih.gov/11987794
Publikováno v:
Clinical Science. 104:62P-62P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01fe213d6b732ab2848f80a4e227917b
https://doi.org/10.1042/cs104062p
https://doi.org/10.1042/cs104062p
Publikováno v:
Clinical Science. 103:1P-1P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d8069c59c01a241a21078d3d9c3df37
https://doi.org/10.1042/cs103001p
https://doi.org/10.1042/cs103001p