Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mahesh S. Desai"'
Autor:
Erica T. Grant, Amy Parrish, Marie Boudaud, Oliver Hunewald, Akiyoshi Hirayama, Markus Ollert, Shinji Fukuda, Mahesh S. Desai
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-23 (2024)
Abstract Background Dietary fibers can alter microbial metabolic output in support of healthy immune function; however, the impact of distinct fiber sources and immunomodulatory effects beyond short-chain fatty acid production are underexplored. In a
Externí odkaz:
https://doaj.org/article/c4f3e084b9bf436aa3711d142b248562
Autor:
Joana Gaifem, Ana Mendes-Frias, Mathis Wolter, Alex Steimle, Maria Jose Garzón, Carles Ubeda, Clarisse Nobre, Abigail González, Salomé S. Pinho, Cristina Cunha, Agostinho Carvalho, António Gil Castro, Mahesh S. Desai, Fernando Rodrigues, Ricardo Silvestre
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTInflammatory bowel disease (IBD) is a group of inflammatory conditions of the gastrointestinal tract. The etiology of IBD remains elusive, but the disease is suggested to arise from the interaction of environmental and genetic factors that tr
Externí odkaz:
https://doaj.org/article/901d2df1c4f24487808e4756a780fae5
Autor:
Luisa Kreft, Aloys Schepers, Miriam Hils, Kyra Swiontek, Andrew Flatley, Robert Janowski, Mohammadali Khan Mirzaei, Michael Dittmar, Neera Chakrapani, Mahesh S. Desai, Stefanie Eyerich, Li Deng, Dierk Niessing, Konrad Fischer, Regina Feederle, Simon Blank, Carsten B. Schmidt-Weber, Christiane Hilger, Tilo Biedermann, Caspar Ohnmacht
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The alpha-Gal epitope (α-Gal) with the determining element galactose-α1,3-galactose can lead to clinically relevant allergic reactions and rejections in xenotransplantation. These immune reactions can develop because humans are devoid of this carbo
Externí odkaz:
https://doaj.org/article/252b4a8f311446508d50f98a1e9b29b0
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
ABSTRACT Food safety has considerably improved worldwide, yet infections with foodborne human enteric pathogens, such as Listeria spp. and Salmonella spp., still cause numerous hospitalizations and fatalities. Since dietary alterations, including fib
Externí odkaz:
https://doaj.org/article/42f41da632944588abb2ddc253ae7778
Autor:
Alex Steimle, Alessandro De Sciscio, Mareike Neumann, Erica T. Grant, Gabriel V. Pereira, Hiroshi Ohno, Eric C. Martens, Mahesh S. Desai
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100607- (2021)
Summary: Reproducible in vivo models are necessary to address functional aspects of the gut microbiome in various diseases. Here, we present a gnotobiotic mouse model that allows for the investigation of specific microbial functions within the microb
Externí odkaz:
https://doaj.org/article/faee353c464c4ed4ad015b89830f2e5b
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100326- (2021)
Summary: The gut microbiome expresses a multitude of enzymes degrading polysaccharides in dietary plant fibers and in host-secreted mucus. The quantitative detection of these glycan-degrading enzymes in fecal samples is important to elucidate the fun
Externí odkaz:
https://doaj.org/article/d0e012e970f44cf9a125e145b17fb9d7
Autor:
Isabel Moreno-Indias, Leo Lahti, Miroslava Nedyalkova, Ilze Elbere, Gennady Roshchupkin, Muhamed Adilovic, Onder Aydemir, Burcu Bakir-Gungor, Enrique Carrillo-de Santa Pau, Domenica D’Elia, Mahesh S. Desai, Laurent Falquet, Aycan Gundogdu, Karel Hron, Thomas Klammsteiner, Marta B. Lopes, Laura Judith Marcos-Zambrano, Cláudia Marques, Michael Mason, Patrick May, Lejla Pašić, Gianvito Pio, Sándor Pongor, Vasilis J. Promponas, Piotr Przymus, Julio Saez-Rodriguez, Alexia Sampri, Rajesh Shigdel, Blaz Stres, Ramona Suharoschi, Jaak Truu, Ciprian-Octavian Truică, Baiba Vilne, Dimitrios Vlachakis, Ercument Yilmaz, Georg Zeller, Aldert L. Zomer, David Gómez-Cabrero, Marcus J. Claesson
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The human microbiome has emerged as a central research topic in human biology and biomedicine. Current microbiome studies generate high-throughput omics data across different body sites, populations, and life stages. Many of the challenges in microbi
Externí odkaz:
https://doaj.org/article/58ddf268165e41df95208c7ec045cc9d
Autor:
Mareike Neumann, Alex Steimle, Erica T. Grant, Mathis Wolter, Amy Parrish, Stéphanie Willieme, Dirk Brenner, Eric C. Martens, Mahesh S. Desai
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
The change of dietary habits in Western societies, including reduced consumption of fiber, is linked to alterations in gut microbial ecology. Nevertheless, mechanistic connections between diet-induced microbiota changes that affect colonization resis
Externí odkaz:
https://doaj.org/article/533332f5f3bf4e4495a6be7d56804884
Autor:
Pranjul Shah, Joëlle V. Fritz, Enrico Glaab, Mahesh S. Desai, Kacy Greenhalgh, Audrey Frachet, Magdalena Niegowska, Matthew Estes, Christian Jäger, Carole Seguin-Devaux, Frederic Zenhausern, Paul Wilmes
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Research on the interactions between the gut microbiota and human cells would greatly benefit from improved in vitro models. Here, Shah et al. present a modular microfluidics-based model that allows co-culture of human and microbial cells followed by
Externí odkaz:
https://doaj.org/article/1c551f94bc624ad09b8ba6bc26235186
In early life, the intestinal mucosa and immune system undergo a critical developmental process to contain the expanding gut microbiome while promoting tolerance towards commensals, yet the influence of maternal diet and gut microbial composition on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf3e41c2907c294697eff99a44117885
https://doi.org/10.1101/2023.03.06.531289
https://doi.org/10.1101/2023.03.06.531289
