Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mahesh S Desai"'
Autor:
Mathis Wolter, Erica T Grant, Marie Boudaud, Nicholas A Pudlo, Gabriel V Pereira, Kathryn A Eaton, Eric C Martens, Mahesh S Desai
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 6, Pp 596-625 (2024)
Abstract The erosion of the colonic mucus layer by a dietary fiber-deprived gut microbiota results in heightened susceptibility to an attaching and effacing pathogen, Citrobacter rodentium. Nevertheless, the questions of whether and how specific muco
Externí odkaz:
https://doaj.org/article/89dec02e572c4e138c2f0fbf88ef302f
Autor:
Rikke Andersen, Josep A Tur, Coralie Dessenne, Farhad Vahid, Cristina Bouzas, Yvan Devaux, Margalida Monserrat-Mesquida, Antoni Sureda, Mahesh S Desai, Jonathan D Turner, Elsa Lamy, Maria Perez-Jimenez, Gitte Ravn-Haren, Rajini Nagrani, Yacine Ouzzahra, Michele Filippo Fontefrancesco, Maria Giovanna Onorati, Gino Gabriel Bonetti
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Introduction Despite international efforts, the number of individuals struggling with obesity is still increasing. An important aspect of obesity prevention relates to identifying individuals at risk at early stage, allowing for timely risk stratific
Externí odkaz:
https://doaj.org/article/b094dc383b3c4a63a9dee245e901229b
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 8, Pp n/a-n/a (2023)
Abstract In early life, the intestinal mucosa and immune system undergo a critical developmental process to contain the expanding gut microbiome while promoting tolerance toward commensals, yet the influence of maternal diet and microbial composition
Externí odkaz:
https://doaj.org/article/20d25f905cb04109874dce0f6d05f9c1
Publikováno v:
Journal of the Scientific Society, Vol 42, Iss 2, Pp 120-122 (2015)
Meckel′s diverticulum is the most common congenital anomaly of the gastrointestinal tract, occurring in about 2% of the population and, in most cases, incidentally being discovered during autopsy, laparotomy, or barium studies. Hemorrhage, obstruct
Externí odkaz:
https://doaj.org/article/cb1deea3115e42899086af4888586f48
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
ABSTRACT Food safety has considerably improved worldwide, yet infections with foodborne human enteric pathogens, such as Listeria spp. and Salmonella spp., still cause numerous hospitalizations and fatalities. Since dietary alterations, including fib
Externí odkaz:
https://doaj.org/article/42f41da632944588abb2ddc253ae7778
Autor:
Mareike Neumann, Alex Steimle, Erica T. Grant, Mathis Wolter, Amy Parrish, Stéphanie Willieme, Dirk Brenner, Eric C. Martens, Mahesh S. Desai
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
The change of dietary habits in Western societies, including reduced consumption of fiber, is linked to alterations in gut microbial ecology. Nevertheless, mechanistic connections between diet-induced microbiota changes that affect colonization resis
Externí odkaz:
https://doaj.org/article/533332f5f3bf4e4495a6be7d56804884
Autor:
Alex Steimle, Mareike Neumann, Erica T. Grant, Stéphanie Willieme, Alessandro De Sciscio, Amy Parrish, Markus Ollert, Eiji Miyauchi, Tomoyoshi Soga, Shinji Fukuda, Hiroshi Ohno, Mahesh S. Desai
Given the gut microbiota’s contribution to pathogenesis of autoimmune diseases, microbiota characteristics could potentially be used to predict disease susceptibility or progression. Although various gut commensals have been proposed as risk factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61885a7bf8a3c5064cb56f52db2d7e15
https://doi.org/10.1101/2023.04.14.536901
https://doi.org/10.1101/2023.04.14.536901
Autor:
Pranjul Shah, Joëlle V. Fritz, Enrico Glaab, Mahesh S. Desai, Kacy Greenhalgh, Audrey Frachet, Magdalena Niegowska, Matthew Estes, Christian Jäger, Carole Seguin-Devaux, Frederic Zenhausern, Paul Wilmes
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Research on the interactions between the gut microbiota and human cells would greatly benefit from improved in vitro models. Here, Shah et al. present a modular microfluidics-based model that allows co-culture of human and microbial cells followed by
Externí odkaz:
https://doaj.org/article/1c551f94bc624ad09b8ba6bc26235186
Autor:
Luisa Kreft, Aloys Schepers, Miriam Hils, Kyra Swiontek, Andrew Flatley, Robert Janowski, Mohammadali Khan Mirzaei, Michael Dittmar, Neera Chakrapani, Mahesh S. Desai, Stefanie Eyerich, Li Deng, Dierk Niessing, Konrad Fischer, Regina Feederle, Simon Blank, Carsten B. Schmidt-Weber, Christiane Hilger, Tilo Biedermann, Caspar Ohnmacht
Publikováno v:
Front. Immunol. 13:958952 (2022)
The alpha-Gal epitope (α-Gal) with the determining element galactose-α1,3-galactose can lead to clinically relevant allergic reactions and rejections in xenotransplantation. These immune reactions can develop because humans are devoid of this carbo
Publikováno v:
Nature reviews. Immunology. 23(1)
The prevalence of autoimmune diseases (ADs) worldwide has rapidly increased over the past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic polymorphisms, infections and smoking, environmental triggers have been co