Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Mahesh N Samtani"'
Autor:
Qingqin S Li, Antonio R Parrado, Mahesh N Samtani, Vaibhav A Narayan, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134000 (2015)
Proteolytic fragments of amyloid and post-translational modification of tau species in Cerebrospinal fluid (CSF) as well as cerebral amyloid deposition are important biomarkers for Alzheimer's Disease. We conducted genome-wide association study to id
Externí odkaz:
https://doaj.org/article/af6a2e86613c4640ab955dc9957e0208
Autor:
Hiroko Shimizu, Marc De Meulder, Bart Remmerie, Yuko Tsukamoto, Mahesh N. Samtani, Srihari Gopal, Martine Neyens
Publikováno v:
Clinical Pharmacology in Drug Development
The paliperidone pharmacokinetics after intramuscular administration of once‐monthly paliperidone palmitate in Japanese patients were studied in 3 phase 1 studies and in 2 phase 3 studies performed in Japan, Korea, and Taiwan. These data (Japanese,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e0881ec18e391474ca121c6f5eab08
https://doi.org/10.1002/cpdd.737
https://doi.org/10.1002/cpdd.737
Publikováno v:
Journal of Clinical Psychopharmacology. 39:567-574
Background Pharmacokinetic-pharmacodynamic (PK/PD) models were developed to describe the relationship between the time course of paliperidone plasma concentrations and the risk of relapse of schizophrenia symptoms following administration of paliperi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e194e9431a76a01ef3013dd476bdaeec
https://doi.org/10.1097/jcp.0000000000001137
https://doi.org/10.1097/jcp.0000000000001137
Autor:
Damien Bonnet, Liping Zhang, Xiangwen Dong, John L. Jefferies, Liza Miriam Pina, Jennifer S. Li, Henri Justino, Kevin C. Harris, Mahesh N. Samtani, Alan D. Michelson, Brian W. McCrindle
Publikováno v:
American Heart Journal. 213:97-104
Background The Fontan procedure is the final step of the 3-stage palliative procedure commonly performed in children with single ventricle physiology. Thrombosis remains an important complication in children after this procedure. To date, guideline r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51236de5604c4d78be545c21e4c7a532
https://doi.org/10.1016/j.ahj.2019.04.009
https://doi.org/10.1016/j.ahj.2019.04.009
Publikováno v:
Frontiers in Anti-Infective Drug Discovery: Volume 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e058fc601d955371a8ea75ea2f319e31
https://doi.org/10.2174/9781681088297121090003
https://doi.org/10.2174/9781681088297121090003
Autor:
Nicholas A. Di Prospero, Penny Fleck, Jaqueline Yee, Maria Alba, Mahesh N. Samtani, Mary Ellen Frustaci
Publikováno v:
Clinical Obesity. 11
Weight loss has been shown to improve metabolic parameters and cardiovascular risk in people with type 2 diabetes mellitus (T2DM). This phase 2 study evaluated the safety and efficacy of JNJ-64565111, a dual agonist of GLP-1 and glucagon receptors, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5abc958868b90c0071e45afcb4033b9
https://doi.org/10.1111/cob.12433
https://doi.org/10.1111/cob.12433
Publikováno v:
Clinical obesityREFERENCES. 11(2)
Individuals with obesity have a heightened risk of developing serious comorbidities, and pharmacological treatments for people with obesity are limited. This phase 2 study assessed the safety and efficacy of JNJ-64565111, a dual agonist of glucagon-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1815c3287aa20a0864bb0bb093c9d62
https://pubmed.ncbi.nlm.nih.gov/33475255
https://pubmed.ncbi.nlm.nih.gov/33475255
Autor:
Partha Nandy, David Hough, Ellen Z. Baum, Mahesh N. Samtani, Alberto Russu, Bart Remmerie, Paulien Ravenstijn, Peter D'hoore, Srihari Gopal, Adam Savitz, An Vermeulen
Publikováno v:
British Journal of Clinical Pharmacology. 82:1364-1370
Aims To prospectively select the dose of the paliperidone palmitate 3-month (PP3M) formulation, using a pharmacometric bridging strategy based on the paliperidone palmitate 1-month (PP1M) formulation previously approved for schizophrenia treatment. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d802e5f6f781a717d55279b1f98c6aa
https://doi.org/10.1111/bcp.13050
https://doi.org/10.1111/bcp.13050
Autor:
Omoniyi J. Adedokun, Alberto Russu, Kaori Ito, Scot Styren, Chuanpu Hu, Steven Xu, Mahesh N. Samtani, H. Robert Brashear, Ming Lu, Brian Corrigan, Sangeeta Raje
Publikováno v:
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Introduction The objective of this study was to estimate longitudinal changes in disease progression (measured by Alzheimer's disease assessment scale-cognitive 11-item [ADAS-cog/11] scale) after bapineuzumab treatment and to identify covariates (dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93752999619c2aafa05957e4bb63a6ee
Autor:
Paulien Ravenstijn, Adam Savitz, Bart Remmerie, David Hough, Srihari Gopal, Isaac Nuamah, Marc De Meulder, Cheng‐Tao Chang, Mahesh N. Samtani
Publikováno v:
The Journal of Clinical Pharmacology. 56:330-339
This multicenter, randomized, open-label, parallel-group, phase-1 study assessed the pharmacokinetics (PK), safety, and tolerability of the investigational intramuscular paliperidone palmitate 3-month (PP3M) formulation in patients with schizophrenia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91cbc75325b0f9814bc78d8f12478883
https://doi.org/10.1002/jcph.597
https://doi.org/10.1002/jcph.597