Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mahesh M Karnani"'
Autor:
Sarah Hunt, Yoni Leibner, Eline J Mertens, Natalí Barros-Zulaica, Lida Kanari, Tim S Heistek, Mahesh M Karnani, Romy Aardse, René Wilbers, Djai B Heyer, Natalia A Goriounova, Matthijs B Verhoog, Guilherme Testa-Silva, Joshua Obermayer, Tamara Versluis, Ruth Benavides-Piccione, Philip de Witt-Hamer, Sander Idema, David P Noske, Johannes C Baayen, Ed S Lein, Javier DeFelipe, Henry Markram, Huibert D Mansvelder, Felix Schürmann, Idan Segev, Christiaan P J de Kock
Publikováno v:
Hunt, S, Leibner, Y, Mertens, E J, Barros-Zulaica, N, Kanari, L, Heistek, T S, Karnani, M M, Aardse, R, Wilbers, R, Heyer, D B, Goriounova, N A, Verhoog, M B, Testa-Silva, G, Obermayer, J, Versluis, T, Benavides-Piccione, R, de Witt-Hamer, P, Idema, S, Noske, D P, Baayen, J C, Lein, E S, DeFelipe, J, Markram, H, Mansvelder, H D, Schürmann, F, Segev, I & de Kock, C P J 2023, ' Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex ', Cerebral cortex (New York, N.Y. : 1991), vol. 33, no. 6, pp. 2857-2878 . https://doi.org/10.1093/cercor/bhac246
Cerebral cortex (New York, N.Y. : 1991), 33(6), 2857-2878. Oxford University Press
Hunt, S, Leibner, Y, Mertens, E J, Barros-Zulaica, N, Kanari, L, Heistek, T S, Karnani, M M, Aardse, R, Wilbers, R, Heyer, D B, Goriounova, N A, Verhoog, M B, Testa-Silva, G, Obermayer, J, Versluis, T, Benavides-Piccione, R, de Witt-Hamer, P, Idema, S, Noske, D P, Baayen, J C, Lein, E S, DeFelipe, J, Markram, H, Mansvelder, H D, Schürmann, F, Segev, I & de Kock, C P J 2023, ' Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex ', Cerebral cortex (New York, N.Y. : 1991), vol. 33, no. 6, pp. 2857-2878 . https://doi.org/10.1093/cercor/bhac246, https://doi.org/10.1093/cercor/bhac246
Cerebral cortex (New York, N.Y. : 1991), 33(6), 2857-2878. Oxford University press
Cerebral cortex (New York, N.Y. : 1991), 33(6), 2857-2878. Oxford University Press
Hunt, S, Leibner, Y, Mertens, E J, Barros-Zulaica, N, Kanari, L, Heistek, T S, Karnani, M M, Aardse, R, Wilbers, R, Heyer, D B, Goriounova, N A, Verhoog, M B, Testa-Silva, G, Obermayer, J, Versluis, T, Benavides-Piccione, R, de Witt-Hamer, P, Idema, S, Noske, D P, Baayen, J C, Lein, E S, DeFelipe, J, Markram, H, Mansvelder, H D, Schürmann, F, Segev, I & de Kock, C P J 2023, ' Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex ', Cerebral cortex (New York, N.Y. : 1991), vol. 33, no. 6, pp. 2857-2878 . https://doi.org/10.1093/cercor/bhac246, https://doi.org/10.1093/cercor/bhac246
Cerebral cortex (New York, N.Y. : 1991), 33(6), 2857-2878. Oxford University press
Synaptic transmission constitutes the primary mode of communication between neurons. It is extensively studied in rodent but not human neocortex. We characterized synaptic transmission between pyramidal neurons in layers 2 and 3 using neurosurgically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91045113000d5b810c2551415662a60a
https://doi.org/10.1093/cercor/bhac246
https://doi.org/10.1093/cercor/bhac246
Autor:
Paulius Viskaitis, Alexander L. Tesmer, Mahesh M. Karnani, Myrtha Arnold, Dane Donegan, Ed F. Bracey, Nikola Grujic, Daria Peleg-Raibstein, Denis Burdakov
Blood glucose variability shapes human brain performance and diverse clinical outcomes. However, it remains poorly understood how blood glucose fluctuations are decoded by genetically-defined neurons to change brain activity and behavior. Recent brea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cfcb1594e5f84139ed83b4661a86d38
https://doi.org/10.1101/2022.04.14.488310
https://doi.org/10.1101/2022.04.14.488310
Autor:
Denis Burdakov, Mahesh M. Karnani
Publikováno v:
Neuroanatomy and behaviour
Burdakov, D & Karnani, M M 2021, ' Orexin neuron activity in mating mice-a pilot study ', Neuroanatomy and behaviour, vol. 3, no. 1, pp. e17 . https://doi.org/10.35430/nab.2021.e17
Neuroanatomy and Behaviour; Vol. 3 (2021): 2021; e17
Neuroanatomy and Behaviour
Neuroanatomy and Behaviour, 2021, 3, pp.e17. ⟨10.35430/nab.2021.e17⟩
Neuroanatomy and behaviour, 3(1)
Neuroanatomy and Behaviour, Vol 3, Pp e17-e17 (2021)
Burdakov, D & Karnani, M M 2021, ' Orexin neuron activity in mating mice-a pilot study ', Neuroanatomy and behaviour, vol. 3, no. 1, pp. e17 . https://doi.org/10.35430/nab.2021.e17
Neuroanatomy and Behaviour; Vol. 3 (2021): 2021; e17
Neuroanatomy and Behaviour
Neuroanatomy and Behaviour, 2021, 3, pp.e17. ⟨10.35430/nab.2021.e17⟩
Neuroanatomy and behaviour, 3(1)
Neuroanatomy and Behaviour, Vol 3, Pp e17-e17 (2021)
International audience; Mating behaviours affect hypothalamic orexin/hypocretin neurons and vice versa. However, activity of orexin neurons has not been recorded during mating before. We report an anecdotal dataset of freely-moving miniature microsco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea6eb3e040b9bbb542e87bcbe555ff3
https://pubmed.ncbi.nlm.nih.gov/34426801
https://pubmed.ncbi.nlm.nih.gov/34426801
Autor:
Mahesh M. Karnani, Han-Tao Li, Paulius Viskaitis, Denis Burdakov, Cornelia Schöne, Edward F. Bracey, J. Antonio González, Antoine Roger Adamantidis
Publikováno v:
Progress in Neurobiology
Karnani, Mahesh M; Schöne, Cornelia; Bracey, Edward F; González, J Antonio; Viskaitis, Paulius; Li, Han-Tao; Adamantidis, Antoine Roger; Burdakov, Denis (2020). Role of spontaneous and sensory orexin network dynamics in rapid locomotion initiation. Progress in neurobiology, 187, p. 101771. Elsevier 10.1016/j.pneurobio.2020.101771
Progress in Neurobiology, 187
Karnani, Mahesh M; Schöne, Cornelia; Bracey, Edward F; González, J Antonio; Viskaitis, Paulius; Li, Han-Tao; Adamantidis, Antoine Roger; Burdakov, Denis (2020). Role of spontaneous and sensory orexin network dynamics in rapid locomotion initiation. Progress in neurobiology, 187, p. 101771. Elsevier 10.1016/j.pneurobio.2020.101771
Progress in Neurobiology, 187
Graphical abstract
Highlights • Hypocretin/orexin neuron (HON) activation correlates with and is causally linked to locomotion initiation. • HONs constitute 5 subtypes based on their dynamics before and during locomotion. • About 2/3 HONs
Highlights • Hypocretin/orexin neuron (HON) activation correlates with and is causally linked to locomotion initiation. • HONs constitute 5 subtypes based on their dynamics before and during locomotion. • About 2/3 HONs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c54090c1b02c829e04670a8ebbe764f
https://pubmed.ncbi.nlm.nih.gov/32058043
https://pubmed.ncbi.nlm.nih.gov/32058043
Autor:
Mahesh M. Karnani, Denis Burdakov
Publikováno v:
Current Biology-CB
Current Biology-CB, Elsevier, 2020, 30, pp.4063-4070.e2. ⟨10.1016/j.cub.2020.07.061⟩
Current Biology, 30 (20)
Current Biology
Current Biology-CB, Elsevier, 2020, 30, pp.4063-4070.e2. ⟨10.1016/j.cub.2020.07.061⟩
Current Biology, 30 (20)
Current Biology
Summary The lateral hypothalamic area (LH) is a vital controller of arousal, feeding, and metabolism [1, 2], which integrates external and internal sensory information. Whereas sensory and whole-body output properties of LH cell populations have rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a964330c29e11e99d4bb5857bb6153
Autor:
J. A. Gonzalez, Mahesh M. Karnani, Edward F. Bracey, Denis Burdakov, C. Schöne, Paulius Viskaitis, Antoine Roger Adamantidis
Internally and externally triggered movement is crucial for survival and is controlled by multiple interconnected neuronal populations spanning many brain areas. Lateral hypothalamic orexin/hypocretin neurons are thought to play a slow, modulatory pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a971bb4317a268fb15a49782eb5437
Publikováno v:
The Journal of Neuroscience. 36:11498-11509
Neuronal tuning, defined by the degree of selectivity to a specific stimulus, is a hallmark of cortical computation. Understanding the role of GABAergic interneurons in shaping cortical tuning is now possible with the ability to manipulate interneuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30333c0888e4ef0961ecdc664c20f097
https://doi.org/10.1523/jneurosci.1920-16.2016
https://doi.org/10.1523/jneurosci.1920-16.2016
Publikováno v:
Journal of Neurophysiology. 115:3008-3017
GABAergic interneurons are positioned to powerfully influence the dynamics of neural activity, yet the interneuron-mediated circuit mechanisms that control spontaneous and evoked neocortical activity remains elusive. Vasoactive intestinal peptide (VI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3382f0a4bb9ccdac1796a4f3836c45b3
https://doi.org/10.1152/jn.01124.2015
https://doi.org/10.1152/jn.01124.2015
Autor:
Jesse Jackson, Inbal Ayzenshtat, Azadeh Hamzehei Sichani, Rafael Yuste, Samuel Kim, Mahesh M. Karnani, Kasra Manoocheri
Publikováno v:
The Journal of Neuroscience. 36:3471-3480
Inhibitory interneurons in the neocortex often connect in a promiscuous and extensive fashion, extending a “blanket of inhibition” on the circuit. This raises the problem of how can excitatory activity propagate in the midst of this widespread in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f70126202f1155ecbf482b507331ff6
https://doi.org/10.1523/jneurosci.3646-15.2016
https://doi.org/10.1523/jneurosci.3646-15.2016
Publikováno v:
Neuron
Summary The claustrum is a small subcortical nucleus that has extensive excitatory connections with many cortical areas. While the anatomical connectivity from the claustrum to the cortex has been studied intensively, the physiological effect and und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfc107045d2c2ea3eca426b5d38ab42
https://pubmed.ncbi.nlm.nih.gov/30154508
https://pubmed.ncbi.nlm.nih.gov/30154508