Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Mahesh Kc"'
1
Akademický článek
Three SARS-CoV-2 spike protein variants delivered intranasally by measles and mumps vaccines are broadly protective
Autor: Yuexiu Zhang, Michelle Chamblee, Jiayu Xu, Panke Qu, Mohamed M. Shamseldin, Sung J. Yoo, Jack Misny, Ilada Thongpan, Mahesh KC, Jesse M. Hall, Yash A. Gupta, John P. Evans, Mijia Lu, Chengjin Ye, Cheng Chih Hsu, Xueya Liang, Luis Martinez-Sobrido, Jacob S. Yount, Prosper N. Boyaka, Shan-Lu Liu, Purnima Dubey, Mark E. Peeples, Jianrong Li
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract As the new SARS-CoV-2 Omicron variants and subvariants emerge, there is an urgency to develop intranasal, broadly protective vaccines. Here, we developed highly efficacious, intranasal trivalent SARS-CoV-2 vaccine candidates (TVC) based on t
Externí odkaz: https://doaj.org/article/8d4eee26f0fd4441806ce1eeeb848da8
Zobrazit plný text záznamu
2
Akademický článek
Influenza A virus modulates ACE2 expression and SARS-CoV-2 infectivity in human cardiomyocytes
Autor: Qian Wu, Naresh Kumar, William P. Lafuse, Omar Santiagonunez Ahumada, Noushin Saljoughian, Elizabeth Whetstone, Ashley Zani, Ashley K. Patton, Mona El Refaey, Amy Webb, Maciej Pietrzak, Lianbo Yu, Mahesh KC, Mark E. Peeples, Latha P. Ganesan, Jacob S. Yount, Murugesan V.S. Rajaram
Publikováno v: iScience, Vol 25, Iss 12, Pp 105701- (2022)
Summary: Influenza A virus (IAV) and SARS-CoV-2 virus are both acute respiratory viruses currently circulating in the human population. This study aims to determine the impact of IAV infection on SARS-CoV-2 pathogenesis and cardiomyocyte function. In
Externí odkaz: https://doaj.org/article/ed34aa95c1dc47edbee86bf7276a8316
Zobrazit plný text záznamu
3
Akademický článek
Avian Toll-like receptor 3 isoforms and evaluation of Toll-like receptor 3–mediated immune responses using knockout quail fibroblast cells
Autor: Mahesh KC, John M. Ngunjiri, Joonbum Lee, Jinsoo Ahn, Mohamed Elaish, Amir Ghorbani, Michael E.C. Abundo, Kichoon Lee, Chang-Won Lee
Publikováno v: Poultry Science, Vol 99, Iss 12, Pp 6513-6524 (2020)
Toll-like receptor 3 (TLR3) induces host innate immune response on recognition of viral double-stranded RNA (dsRNA). Although several studies of avian TLR3 have been reported, none of these studies used a gene knockout (KO) model to directly assess i
Externí odkaz: https://doaj.org/article/9dfccae0cef446528782a333ad927387
Zobrazit plný text záznamu
4
Akademický článek
Influenza A virus infection in turkeys induces respiratory and enteric bacterial dysbiosis correlating with cytokine gene expression
Autor: John M. Ngunjiri, Kara J.M. Taylor, Hana Ji, Michael C. Abundo, Amir Ghorbani, Mahesh KC, Chang-Won Lee
Publikováno v: PeerJ, Vol 9, p e11806 (2021)
Turkey respiratory and gut microbiota play important roles in promoting health and production performance. Loss of microbiota homeostasis due to pathogen infection can worsen the disease or predispose the bird to infection by other pathogens. While t
Externí odkaz: https://doaj.org/article/86723a96cfa34c9093d58aca9d8dab5e
Zobrazit plný text záznamu
5
Akademický článek
Efficacy and synergy of live-attenuated and inactivated influenza vaccines in young chickens.
Autor: Hyesun Jang, Mohamed Elaish, Mahesh Kc, Michael C Abundo, Amir Ghorbani, John M Ngunjiri, Chang-Won Lee
Publikováno v: PLoS ONE, Vol 13, Iss 4, p e0195285 (2018)
Outbreaks of novel highly pathogenic avian influenza viruses have been reported in poultry species in the United States since 2014. These outbreaks have proven the limitations of biosecurity control programs, and new tools are needed to reinforce the
Externí odkaz: https://doaj.org/article/fad9201142a743d9a983a6918f3aec58
Zobrazit plný text záznamu
6
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje