Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mahesh Kathania."'
Autor:
Wook Jin, MD, Dong-Hwa Yang, MD, Hann Tchah, MD, Kwang-An Kwon, MD, Jung-Ho Kim, MD, Su-Jin Jeong, MD, Ki-Baik Hahm, MD, Mahesh Kathania.
Publikováno v:
Medicine, Vol 101, Iss 20, p e29296 (2022)
Abstract. Several studies have shown an association between sarcopenia and clinical outcomes in patients with Crohn's disease (CD). However, studies have shown different results, and the association between prognosis and wasting conditions in pediatr
Externí odkaz:
https://doaj.org/article/239da0557ce342168774b5eff4253aac
Autor:
Amir Kumar Singh, Ritesh Kumar, Jianyi Yin, John F. Brooks II, Mahesh Kathania, Sandip Mukherjee, Jitendra Kumar, Kevin P. Conlon, Venkatesha Basrur, Zhe Chen, Xianlin Han, Lora V. Hooper, Ezra Burstein, K. Venuprasad
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Th17 cells that produce Interleukin IL-17 are pathogenic in many human diseases, including inflammatory bowel disease, but are, paradoxically, essential for maintaining the integrity of the intestinal barrier in a non-inflammatory state. How
Externí odkaz:
https://doaj.org/article/befedf1f83644092980fd717763deaa0
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background Chimeric antigen receptor (CAR) T-cell therapy is an emerging option for cancer treatment, but its efficacy is limited, especially in solid tumors. This is partly because the CAR T cells become dysfunctional and exhausted in the tumor micr
Externí odkaz:
https://doaj.org/article/46fdf68b933c4b81816f119845ff0132
Autor:
Mahesh Kathania, Ritesh Kumar, Elviche Taskem Lenou, Venkatesha Basrur, Arianne L. Theiss, Jonathan Chernoff, K. Venuprasad
Publikováno v:
Cell Reports. 40:111345
Dysregulated interleukin-17 (IL-17) expression and its downstream signaling is strongly linked to inflammatory bowel diseases (IBDs). However, the molecular mechanisms by which the function of RORγt, the transcription factor of IL-17, is regulated r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd75b9c567b086ee50e03a37f023f6a
https://doi.org/10.1016/j.celrep.2022.111345
https://doi.org/10.1016/j.celrep.2022.111345
Autor:
Matthew J. Riese, K. Venuprasad, Ritesh Kumar, Arianne L. Theiss, Elviche L. Tsakem, Jitendra Kumar, Marco L. Davila, Mahesh Kathania, Amir Kumar Singh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundChimeric antigen receptor (CAR) T-cell therapy is an emerging option for cancer treatment, but its efficacy is limited, especially in solid tumors. This is partly because the CAR T cells become dysfunctional and exhausted in the tumor micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299f89e9b8bd48608abf6fa41389fcc8
https://jitc.bmj.com/content/9/1/e001688.full
https://jitc.bmj.com/content/9/1/e001688.full
Autor:
Mahesh Kathania, Mojgan Zadeh, Yaíma L Lightfoot, Robert M Roman, Bikash Sahay, Jeffrey R Abbott, Mansour Mohamadzadeh
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55143 (2013)
Currently, sufficient data exist to support the use of lactobacilli as candidates for the development of new oral targeted vaccines. To this end, we have previously shown that Lactobacillus gasseri expressing the protective antigen (PA) component of
Externí odkaz:
https://doaj.org/article/c5d36c0cea254bee907826aef2a7410a
Autor:
Mahesh Kathania, T L Elviche, K. Venuprasad, Venkatesha Basrur, Minghui Zeng, Joydeep Paul, Arianne L. Theiss, A K Singh
Publikováno v:
Mucosal Immunology. 11:427-436
Intestinal fibrosis is a major complication in inflammatory bowel diseases, but the regulatory mechanism that inhibits fibrosis remains unclear. Here we demonstrate that Itch-/-myofibroblasts express increased amounts of profibrotic collagen type I a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7563f2eb10b7677fb9c849b4d536760
https://doi.org/10.1038/mi.2017.53
https://doi.org/10.1038/mi.2017.53
Autor:
Amika Singla, Steven M. Harrison, Jonathan J. Rios, Haiying Li, Petro Starokadomskyy, Qi Liu, Linda A. Baker, Nicholas Norris, Ernesto M. Llano, Purva Gopal, Da Jia, Lillienne Chan, Jason Y. Park, Mahesh Kathania, Theodora S. Ross, Shuai Tan, Ashish S. Patel, Luis Sifuentes-Dominguez, Zhe Liu, Ezra Burstein, K. Venuprasad, Areen Khoury
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Inflammatory bowel disease (IBD) affects 1.5–3.0 million people in the United States. IBD is genetically determined and many common risk alleles have been identified. Yet, a large proportion of genetic predisposition remains unexplained. In this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25402fe10f013b6be2d0543b843a394c
https://doi.org/10.7554/elife.49910
https://doi.org/10.7554/elife.49910
Autor:
Ezra Burstein, K. Venuprasad, Jason Y. Park, Ashish S. Patel, Qi Liu, Steven M. Harrison, Mahesh Kathania, Theodora S. Ross, Luis Sifuentes-Dominguez, Amika Singla, Areen Khoury, Shuai Tan, Lillienne Chan, Haiying Li, Petro Starokadomskyy, Nicholas Norris, Linda A. Baker, Zhe Liu, Jonathan J. Rios, Da Jia, Ernesto M. Llano, Purva Gopal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d085f616545487f45bbbbc68c623ec05
https://doi.org/10.7554/elife.49910.053
https://doi.org/10.7554/elife.49910.053
Publikováno v:
J Immunol
Inflammatory bowel diseases are associated with complex shifts in microbiota composition. However, it remains unclear whether specific subsets of commensal bacteria induce inflammatory bowel diseases in genetically susceptible hosts. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a866ff74e3c76f937acd54e67cd233a7
https://pubmed.ncbi.nlm.nih.gov/32169841
https://pubmed.ncbi.nlm.nih.gov/32169841