Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mahesh Gokara"'
Autor:
Archit Garg, Darla Mark Manidhar, Mahesh Gokara, Chandramouli Malleda, Cirandur Suresh Reddy, Rajagopal Subramanyam
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63805 (2013)
Coumarin is a benzopyrone which is widely used as an anti-coagulant, anti-oxidant, anti-cancer and also to cure arthritis, herpes, asthma and inflammation. Here, we studied the binding of synthesized coumarin derivatives with human serum albumin (HSA
Externí odkaz:
https://doaj.org/article/0652eaf58e04493c9b963c549c485abe
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8834 (2010)
BACKGROUND: Human serum albumin (HSA) is the most abundant protein in blood plasma, having high affinity binding sites for several endogenous and exogenous compounds. Trimethoxy flavone (TMF) is a naturally occurring flavone isolated from Andrographi
Externí odkaz:
https://doaj.org/article/a6e0e19fe6a142819158f6e7a1419487
Publikováno v:
Gene. 656:22-29
Molecular diagnostics is of critical importance to public health worldwide. It facilitates not only detection and characterization of diseases, but also monitors drug responses, assists in the identification of genetic modifiers and disease susceptib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08da231f1d59431de296da4df7cd3782
https://doi.org/10.1016/j.gene.2018.02.066
https://doi.org/10.1016/j.gene.2018.02.066
Autor:
Mahesh Gokara, Sreelaxmi Varkala, Vidadala V. Narayana, Dhevalapally B. Ramachary, Rajagopal Subramanyam, Shatabdi Roy Chowdhury, Vineet Sadarangani
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 35:2280-2292
In this study, molecular binding affinity was investigated for Nefopam analogues (NFs), a functionalized benzoxazocine, with human serum albumin (HSA), a major transport protein in the blood. Its binding affinity and concomitant changes in its confor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6945b8b59e2f6a79546ba5c8f5e233f
https://doi.org/10.1080/07391102.2016.1216895
https://doi.org/10.1080/07391102.2016.1216895
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 33:196-210
Chitosan is a naturally occurring deacetylated derivative of chitin with versatile biological activities. Here, we studied the interaction of chitosan oligomers with low degree of polymerization such as chitosan monomer (CM), chitosan dimer (CD), and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c60f745f2a468a43e6a6d528a99de5
https://doi.org/10.1080/07391102.2013.868321
https://doi.org/10.1080/07391102.2013.868321
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 32:1290-1302
Asiatic acid (AsA), a naturally occurring pentacyclictriterpenoid found in Centella asiatica, plays a major role in neuroprotection, anticancer, antioxidant, and hepatoprotective activities. Human serum albumin (HSA), a blood plasma protein, particip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d250ca5b6a93152bd1593ba4e6805367
https://doi.org/10.1080/07391102.2013.817953
https://doi.org/10.1080/07391102.2013.817953
Publikováno v:
The Journal of Physical Chemistry B. 114:9054-9062
Beta-sitosterol is a naturally occurring phytosterol that is widely used to cure atherosclerosis, diabetes, cancer, and inflammation and is also an antioxidant. Here, we studied the interaction of beta-sitosterol, isolated from the aerial roots of Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e0488d9b6d65bfd581cc42b94a92c8
https://doi.org/10.1021/jp102730p
https://doi.org/10.1021/jp102730p
Autor:
Daniel Pushparaju Yeggoni, Aparna Rachamallu, Rajagopal Subramanyam, Mahesh Gokara, Sailaja Nakka, Cirandur Suresh Reddy, Darla Mark Manidhar
Publikováno v:
Molecular pharmaceutics. 11(4)
Human serum albumin (HSA) is one of the most widely studied proteins and is an important plasma protein responsible for binding and transport of many exogenous and endogenous drugs. Coumarin derivatives play a critical role as anticancer, antidiabeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5629e1a46bddd666c9856a278a6a235
https://pubmed.ncbi.nlm.nih.gov/24495045
https://pubmed.ncbi.nlm.nih.gov/24495045
Autor:
Mahesh Gokara, Chandramouli Malleda, Rajagopal Subramanyam, Cirandur Suresh Reddy, Darla Mark Manidhar, Archit Garg
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63805 (2013)
PLoS ONE
PLoS ONE
Coumarin is a benzopyrone which is widely used as an anti-coagulant, anti-oxidant, anti-cancer and also to cure arthritis, herpes, asthma and inflammation. Here, we studied the binding of synthesized coumarin derivatives with human serum albumin (HSA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a166c529f214a278990a16c7a40a9259
http://europepmc.org/articles/PMC3665821?pdf=render
http://europepmc.org/articles/PMC3665821?pdf=render
Publikováno v:
The journal of physical chemistry. B. 114(8)
N-trans-p-coumaroyltyramine (CT) isolated from Physalis minima is a phenolic substance exhibiting many pharmacological activities like potent inhibition of acetyl cholinesterase, cell proliferation, platelet aggregation, and also antioxidant activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da34de6c36444494f8f2866b3ddc53b
https://pubmed.ncbi.nlm.nih.gov/20136105
https://pubmed.ncbi.nlm.nih.gov/20136105