Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mahesh Chemudupati"'
Autor:
Mahesh Chemudupati, Temet M. McMichael, Ashley Zani, Adam D. Kenney, Serena Bonifati, Li Wu, Jacob S. Yount
Publikováno v:
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
Antiviral restriction factors are cellular proteins that inhibit the entry, replication, or spread of viruses. These proteins are critical components of the innate immune system and function to limit the severity and host range of virus infections. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773cc932c3a7aee82765b358dfd345d5
Autor:
Amit Sharma, Anna C. Smith, Adam D. Kenney, Lizhi Zhang, Shan-Lu Liu, Ashley Zani, Jacob S. Yount, Mahesh Chemudupati, Robert J. Fillinger, Matthew Z. Anderson
Publikováno v:
J Virol
Butyrate is an abundant metabolite produced by gut microbiota. While butyrate is a known histone deacetylase inhibitor that activates expression of many genes involved in immune system pathways, its effects on virus infections and on the antiviral ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fab6c72d4a75267417d640fcab5f621
https://doi.org/10.1128/jvi.00326-20
https://doi.org/10.1128/jvi.00326-20
Autor:
Adam D. Kenney, Lizhi Zhang, Anna C. Smith, Shan-Lu Liu, Amit Sharma, Mahesh Chemudupati, Matthew Z. Anderson, Robert J. Fillinger, Ashley Zani, Jacob S. Yount
Butyrate is an abundant metabolite produced by the gut microbiota and is known to modulate multiple immune system pathways and inflammatory diseases. However, studies of its effects on virus infection of cells are limited and enigmatic. We found that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9acba335bb43c64966d0f527fae00e1
https://doi.org/10.1101/2020.02.04.934919
https://doi.org/10.1101/2020.02.04.934919
Autor:
Temet M. McMichael, Ashley Zani, Jacob S. Yount, Jesse J. Kwiek, Adam D. Kenney, Shan-Lu Liu, Mahesh Chemudupati, Lizhi Zhang
Publikováno v:
J Biol Chem
Type I interferon (IFN) induced by virus infections during pregnancy can cause placental damage, but the mechanisms and identities of IFN-stimulated genes that are involved in this damage remain under investigation. The IFN-induced transmembrane prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ce207839eafb01c7158cb0389c6aec
https://europepmc.org/articles/PMC6937555/
https://europepmc.org/articles/PMC6937555/
Publikováno v:
Fungal genetics and biology : FGB. 130
Nuclear pore complex (NPC) proteins (Nups) play multiple roles during mitosis. In this study we expand these roles and reveal that in Aspergillus nidulans, compromising the core Nup84-120 subcomplex of the NPC modifies the mitotic behavior of the nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306c1a4761df3f33de82d624c0b9cbb7
https://pubmed.ncbi.nlm.nih.gov/31026588
https://pubmed.ncbi.nlm.nih.gov/31026588
Autor:
Adam D. Kenney, Nicholas M. Chesarino, Min Chen, Mahesh Chemudupati, Foued Amari, Murugesan V. S. Rajaram, Vincenzo Coppola, Alexander Imas, Temet M. McMichael, Qian Wu, Omar Alfaour, Federica Accornero, Ashley Zani, Lisa E. Dorn, Lizhi Zhang, Jacob S. Yount
Influenza virus can disseminate from the lungs to the heart in severe infections and can induce cardiac pathology, but this has been difficult to study due to a lack of small animal models. In humans, polymorphisms in the gene encoding the antiviral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e81eaad5a9ff31a09194f0abee7495
https://doi.org/10.1101/518548
https://doi.org/10.1101/518548
Publikováno v:
Molecular Biology of the Cell
Study of mitotic redistribution of Gle1 in Aspergillus nidulans identified an orthologue of fission yeast Bqt4, an inner nuclear membrane protein required for meiosis. This protein—MtgA for “mitotic tether for Gle1”—also modulates nucleolar a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67689d951ac577cb2999d9cc56fcf5ae
https://doi.org/10.1091/mbc.e16-07-0544
https://doi.org/10.1091/mbc.e16-07-0544
Autor:
Ashley Zani, Adam D. Kenney, Lizhi Zhang, Temet M. McMichael, Jacob S. Yount, Mijia Lu, Jianrong Li, Mahesh Chemudupati, Yu Zhang
Publikováno v:
The Journal of Infectious Diseases.
Human metapneumovirus (hMPV) utilizes a bifurcated cellular entry strategy, fusing either with the plasma membrane or, after endocytosis, with the endosome membrane. Whether cellular factors restrict or enhance either entry pathway is largely unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196b43b74fbc56039897afd3a21c20fb
https://doi.org/10.1093/infdis/jiy361
https://doi.org/10.1093/infdis/jiy361
Autor:
Jianrong Li, Adam D. Kenney, Mahesh Chemudupati, Temet M. McMichael, Ashley Zani, Jacob S. Yount, Lizhi Zhang, Mijia Lu, Yu Zhang
Human metapneumovirus (hMPV) utilizes a bifurcated cellular entry strategy, fusing either with the plasma membrane or, after endocytosis, with the endosome membrane. Whether cellular factors restrict or enhance either entry pathway is largely unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a236beeae11f919a36e17afc9a6417
https://doi.org/10.1101/290957
https://doi.org/10.1101/290957
Publikováno v:
Cellularmolecular immunology. 15(10)
Interferon-induced transmembrane protein 3 (IFITM3) is a restriction factor that can be induced by viral infection and interferons (IFNs). It inhibits the entry and replication of many viruses, which are independent of receptor usage but dependent on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be404ce57b62bc1da8d5a6c09188cae6
https://pubmed.ncbi.nlm.nih.gov/28435159
https://pubmed.ncbi.nlm.nih.gov/28435159