Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mahesh Chaubal"'
Autor:
Lee Sarah, Yong Zhang, Lawrence Lin, Robert M. Hoffman, Jerome H. Gass, Mahesh Chaubal, Barrett E. Rabinow, Shawn F. Bairstow, M.A. Murphy, Zhijian Yang, Jane Werling, Xiaoen Wang, James P. DiOrio
Publikováno v:
Pharmaceutical Development and Technology. 19:438-453
The purpose of this work was to prepare a stable paclitaxel nanosuspension and test it for potential use as a targeted chemotherapeutic. Different particle coatings were employed to assess their impact on cellular uptake in vitro. In vivo work was th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ee195e71f5c97b1d3ef4958cd5eb54
https://doi.org/10.3109/10837450.2013.789911
https://doi.org/10.3109/10837450.2013.789911
Autor:
Mahesh Chaubal, JoEllyn M McMillan, Barrett E. Rabinow, Jane Werling, Howard E. Gendelman, Cassi B. Grotepas, Christopher J. Destache, Huanyu Dou, James E. Kipp
Publikováno v:
The Journal of Immunology. 183:661-669
Antiretroviral therapy (ART) shows variable blood-brain barrier penetration. This may affect the development of neurological complications of HIV infection. In attempts to attenuate viral growth for the nervous system, cell-based nanoformulations wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6c591eef49505ccdce9693fba5624e
https://doi.org/10.4049/jimmunol.0900274
https://doi.org/10.4049/jimmunol.0900274
Autor:
Andrew Brugger, James E. Kipp, Pavlos Papadopoulos, John Ning, Barrett E. Rabinow, Joseph Chung Tak Wong, Atul Khare, Mahesh Chaubal
Publikováno v:
Advanced Drug Delivery Reviews. 60:939-954
There has been growing interest in nanoparticles as an approach to formulate poorly soluble drugs. Besides enhanced dissolution rates, and thereby, improved bioavailability, nanoparticles can also provide targeting capabilities when injected intraven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331a63c088d86eb0bb2412a13d2a7576
https://doi.org/10.1016/j.addr.2007.11.008
https://doi.org/10.1016/j.addr.2007.11.008
Publikováno v:
Advanced Drug Delivery Reviews. 60:757-767
Parenteral formulations, particularly intravascular ones, offer a unique opportunity for direct access to the bloodstream and rapid onset of drug action as well as targeting to specific organ and tissue sites. Triglyceride emulsions, liposomes and mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd01442e9ea401ad9c4abe39ffbd6974
https://doi.org/10.1016/j.addr.2007.10.013
https://doi.org/10.1016/j.addr.2007.10.013
Autor:
Mahesh Chaubal, Christopher J. Destache, Justin R. Morehead, Huanyu Dou, You Zhou, Barrett E. Rabinow, James E. Kipp, Lyudmila S. Shlyakhtenko, Jane Werling, Jeffrey D. Kingsley, Howard E. Gendelman
Publikováno v:
Virology. 358(1):148-158
The effectiveness of anti-retroviral therapies (ART) depends on its ultimate ability to clear reservoirs of continuous human immunodeficiency virus (HIV) infection. We reasoned that a principal vehicle for viral dissemination, the mononuclear phagocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c128b0f0e3ae32d7a1219fbc81424779
Autor:
Theodore J. Roseman, Mahesh Chaubal
Publikováno v:
Drug Delivery System. 21:388-397
Drug delivery technologies for reformulation of parenteral therapeutics has received a lot of attention in recent years, due to significant advances in the field. There is a growing need for patient compliant dosage forms within the cancer therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cf5a0ce134b187fa217f6363f08b3ad
https://doi.org/10.2745/dds.21.388
https://doi.org/10.2745/dds.21.388
Autor:
Mahesh Chaubal
Publikováno v:
Drug Discovery Today. 9:603-609
Formulation development during early drug discovery and lead optimization, involves several challenges including limited drug supply, the need for rapid turnaround, and limited development time. It is also desirable to develop initial formulations th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d98c0393e221d7957e9195fdcd906a1
https://doi.org/10.1016/s1359-6446(04)03171-x
https://doi.org/10.1016/s1359-6446(04)03171-x
Publikováno v:
Journal of Applied Polymer Science. 90:4021-4031
The chemical composition and quantitative molar ratios among all components of biodegradable polyphosphoester copolymers of DL-lactide and ethylphosphate were determined by a comprehensive set of NMR spectroscopic methods. The polyphosphoester copoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5744baf41cc7c02fc04419cb0e914b47
https://doi.org/10.1002/app.13165
https://doi.org/10.1002/app.13165
Autor:
Keith Edward Branham, James Perry English, Eric Spicer, Geraldine Su, Wenbin Dang, Mahesh Chaubal, Zhong Zhao
Publikováno v:
Journal of Biomaterials Science, Polymer Edition. 14:45-61
Poly(lactide-co-ethylphosphate)s, a new class of linear phosphorus-containing copolymers made by chain-extending low-molecular-weight polylactide prepolymers with ethyl dichlorophosphate, were investigated for their in vitro and in vivo degradation m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ebd5b0722c2ab66a4604e3847d7d65
https://doi.org/10.1163/15685620360511137
https://doi.org/10.1163/15685620360511137
Autor:
Mahesh Chaubal, Joseph Chung Tak Wong
Publikováno v:
Pharmaceutical Sciences Encyclopedia
Recent years have seen continued growth in the area of biologics with a majority of pharmaceutical companies developing a pipeline in next-generation biologic products. Most biologics are administered via injectable routes of administration and often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5c9c4c57eeb0aef4d0862547ef6e4df
https://doi.org/10.1002/9780470571224.pse519
https://doi.org/10.1002/9780470571224.pse519
