Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium oxalate stone disease

Autor: Abhishek Albert, Vidhi Tiwari, Eldho Paul, Divya Ganesan, Mahesh Ayyavu, Ritu Kujur, Sasikumar Ponnusamy, Kathiresan Shanmugam, Luciano Saso, Selvam Govindan Sadasivam

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 426-433 (2017)

Oxalates stimulate alterations in renal epithelial cells and thereby induce calcium oxalate (CaOx) stone formation. Bacillus subtilis YvrK gene encodes for oxalate decarboxylase (OxdC) which degrades oxalate to formate and CO2. The present work is ai

Externí odkaz: https://doaj.org/article/3ffb43d45b194d7493b38e8c5dac2fbd

Interaction of rhenium(I) complex carrying long alkyl chain with Calf Thymus DNA: Cytotoxic and cell imaging studies

Autor: Balakrishnan, Gopalakrishnan, Rajendran, Thangamuthu, Senthil Murugan, Krishnan, Sathish Kumar, Mudedla, Sivasubramanian, Veluchamy Kamaraj, Ganesan, Muniyandi, Mahesh, Ayyavu, Thirunalasundari, Thiyagarajan, Rajagopal, Seenivasan

Publikováno v: In Inorganica Chimica Acta 1 August 2015 434:51-59

Triazole based ratiometric fluorescent probe for Zn2+ and its application in bioimaging

Autor: Iniya, Murugan, Jeyanthi, Dharmaraj, Krishnaveni, Karuppiah, Mahesh, Ayyavu, Chellappa, Duraisamy

Publikováno v: In Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 24 February 2014 120:40-46

Cytocompatible chitosan-graft-mPEG-based 5-fluorouracil-loaded polymeric nanoparticles for tumor-targeted drug delivery

Autor: Goutham Nageshwar Rao, Subramanian Natesan, M. Gover Antoniraj, Linda Jeeva Kumari Henry, Ruckmani Kandasamy, D. Sathish Sundar, Mahesh Ayyavu

Publikováno v: Drug Development and Industrial Pharmacy. 44:365-376

Biodegradable materials like chitosan (CH) and methoxy polyethylene glycol (mPEG) are widely being used as drug delivery carriers for various therapeutic applications. In this study, copolymer (CH-g-mPEG) of CH and carboxylic acid terminated mPEG was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb855c7eefdea5a3fb095c5a9b1a362
https://doi.org/10.1080/03639045.2017.1371741

Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium oxalate stone disease

Autor: Sasikumar Ponnusamy, Vidhi Tiwari, Selvam Govindan Sadasivam, Kathiresan Shanmugam, Abhishek Albert, Ritu Kujur, Divya Ganesan, Eldho Paul, Luciano Saso, Mahesh Ayyavu

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 426-433 (2017)
Journal of Enzyme Inhibition and Medicinal Chemistry

Oxalates stimulate alterations in renal epithelial cells and thereby induce calcium oxalate (CaOx) stone formation. Bacillus subtilis YvrK gene encodes for oxalate decarboxylase (OxdC) which degrades oxalate to formate and CO2. The present work is ai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e85d24923557d673635e6dac32d9146
http://hdl.handle.net/11573/1093848