Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Maher Fathalla"'
Autor:
Sobhi M. Gomha, Magdi E.A. Zaki, Deepika Maliwal, Raghuvir R.S. Pissurlenkar, Mohamed S. Ibrahim, Maher Fathalla, Ahmed M. Hussein
Publikováno v:
Results in Chemistry, Vol 6, Iss , Pp 101209- (2023)
The essential enzyme cyclin-dependent kinase 2 (CDK2) is a promising target for anticancer drug development due to its pivotal role in regulating the cell cycle. This study aimed to synthesize novel 3-thiazolyl-indole derivatives and assess their abi
Externí odkaz:
https://doaj.org/article/789210f92c5340a8b06fe5613d8455f2
Autor:
Mohamed S. Ibrahim, Basant Farag, Jehan Y. Al-Humaidi, Magdi E. A. Zaki, Maher Fathalla, Sobhi M. Gomha
Publikováno v:
Molecules, Vol 28, Iss 9, p 3869 (2023)
The development of new approaches for the synthesis of new bioactive heterocyclic derivatives is of the utmost importance for pharmaceutical industry. In this regard, the present study reports the green synthesis of new benzaldazine and ketazine deri
Externí odkaz:
https://doaj.org/article/14ac13f6ff7a4ece9e2946e0a97b4b25
Publikováno v:
Molecules, Vol 28, Iss 2, p 689 (2023)
One crucial strategy for the treatment of breast cancer involves focusing on the Vascular Endothelial Growth Factor Receptor (VEGFR-2) signaling system. Consequently, the development of new (VEGFR-2) inhibitors is of the utmost importance. In this st
Externí odkaz:
https://doaj.org/article/bc7f7fcbb17745f49de4bc671e2d52ad
Autor:
Ashraf S. A. El-Sayed, Maher Fathalla, Ahmed A. Shindia, Amgad M. Rady, Ashraf F. El-Baz, Yara Morsy, Basel Sitohy, Mahmoud Sitohy
Publikováno v:
Scientia Pharmaceutica, Vol 89, Iss 4, p 48 (2021)
Taxadiene synthase (TDS) is the rate-limiting enzyme of Taxol biosynthesis that cyclizes the geranylgeranyl pyrophosphate into taxadiene. Attenuating Taxol productivity by fungi is the main challenge impeding its industrial application; it is possibl
Externí odkaz:
https://doaj.org/article/6b764943a5f54d1ab9556a6845564b1a
Autor:
Ashraf S. A. El-Sayed, Maher Fathalla, Marwa A. Yassin, Nabila Zein, Shaima Morsy, Mahmoud Sitohy, Basel Sitohy
Publikováno v:
Molecules, Vol 25, Iss 2, p 263 (2020)
Taxol is one of the potential anticancer drugs; however, the yield of Taxol and its cytotoxicity are common challenges. Thus, manipulating the Taxol biosynthetic pathway from endophytic fungi, in addition to chemical modification with biocompatible p
Externí odkaz:
https://doaj.org/article/883ce534170d408e9249defbcb5775ac
Publikováno v:
Polycyclic Aromatic Compounds. :1-16
Autor:
Maher Fathalla
Publikováno v:
Journal of Porphyrins and Phthalocyanines. 26:348-354
The innovation of new synthetic strategies to assemble functional materials is of the utmost importance. Herein, a light harvesting [3]rotaxane 7 was designed and synthesized by threading alkyne-functionalized dibenzyl ammonium 5 into dibenzo-24-crow
Autor:
Maher Fathalla
Publikováno v:
Macromolecular Research. 29:321-326
The synthesis, characterization and CO2 uptake tendency of a new porous organic polymer (POP) based on porphyrin-pyromellitic dianhyderide is enclosed. The reported porphyrin POP was achieved by exploiting the condensation reaction between tetraamino
Autor:
Maher Fathalla
Publikováno v:
Journal of Porphyrins and Phthalocyanines. 25:95-101
The development of synthetic strategies for functional building units plays a central role in supramolecular chemistry. Both porphyrin and crown ethers have attracted the attention of researchers worldwide owing to their unique properties. It is envi
Autor:
Maher Fathalla, Lutfan Sinatra
Publikováno v:
Journal of Porous Materials. 28:183-189
Ionic self-assembly (ISA) is a powerful tool that has been exploited to create various functional nanomaterials through the electrostatic interactions of different building blocks. Herein, we disclose for the first time the synthesis and characteriza