Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Maher A Hachem"'
Autor:
Bashar Shuoker, Michael J. Pichler, Chunsheng Jin, Hiroka Sakanaka, Haiyang Wu, Ana Martínez Gascueña, Jining Liu, Tine Sofie Nielsen, Jan Holgersson, Eva Nordberg Karlsson, Nathalie Juge, Sebastian Meier, Jens Preben Morth, Niclas G. Karlsson, Maher Abou Hachem
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
This study offers molecular insight into the sialidase and fucosidase decapping apparatus that initiates growth on mucin and promotes nutrient sharing by the dedicated mucolytic symbiont Akkermansia muciniphila with the mucus-associated microbiota.
Externí odkaz:
https://doaj.org/article/9a041ee102734a0eac2f4911f764b7f1
Autor:
Majid Haddad Momeni, Folmer Fredslund, Bastien Bissaro, Olanrewaju Raji, Thu V. Vuong, Sebastian Meier, Tine Sofie Nielsen, Vincent Lombard, Bruno Guigliarelli, Frédéric Biaso, Mireille Haon, Sacha Grisel, Bernard Henrissat, Ditte Hededam Welner, Emma R. Master, Jean-Guy Berrin, Maher Abou Hachem
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Microbial oxidoreductases are key in biomass breakdown. Here, the authors expand the specificity and redox scope within fungal auxiliary activity 7 family (AA7) enzymes and show that AA7 oligosaccharide dehydrogenases can directly fuel cellulose degr
Externí odkaz:
https://doaj.org/article/0da8e321f452495c9a48a6a598783fe7
Autor:
Majid Haddad Momeni, Maria Louise Leth, Claus Sternberg, Erwin Schoof, Maike Wennekers Nielsen, Jesper Holck, Christopher T. Workman, Jakob Blæsbjerg Hoof, Maher Abou Hachem
Publikováno v:
Biotechnology for Biofuels, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Background Lytic polysaccharide monooxygenases (LPMOs) are often studied in simple models involving activity measurements of a single LPMO or a blend thereof with hydrolytic enzymes towards an insoluble substrate. However, the contribution o
Externí odkaz:
https://doaj.org/article/caa75e35abca4e36ae82ee592d1abef6
Autor:
Michael Jakob Pichler, Chihaya Yamada, Bashar Shuoker, Camila Alvarez-Silva, Aina Gotoh, Maria Louise Leth, Erwin Schoof, Toshihiko Katoh, Mikiyasu Sakanaka, Takane Katayama, Chunsheng Jin, Niclas G. Karlsson, Manimozhiyan Arumugam, Shinya Fushinobu, Maher Abou Hachem
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The assembly and maturation of the early life microbiome has life-long effects on human health. Here, the authors combine omics, functional assays and structural analyses to characterize the catabolic pathways that support the growth of butyrate prod
Externí odkaz:
https://doaj.org/article/93e13acc192c463a8e81c96141510b43
Autor:
Majid Haddad Momeni, Paolo Bollella, Roberto Ortiz, Esben Thormann, Lo Gorton, Maher Abou Hachem
Publikováno v:
BMC Biotechnology, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Laccases are multicopper oxidases, which are assigned into auxiliary activity family 1 (AA1) in the CAZy database. These enzymes, catalyzing the oxidation of phenolic and nonphenolic substrates coupled to reduction of O2 to H2O, a
Externí odkaz:
https://doaj.org/article/9a84675ee561499185dccad3bb47ddc5
Autor:
Sabina Leanti La Rosa, Maria Louise Leth, Leszek Michalak, Morten Ejby Hansen, Nicholas A. Pudlo, Robert Glowacki, Gabriel Pereira, Christopher T. Workman, Magnus Ø. Arntzen, Phillip B. Pope, Eric C. Martens, Maher Abou Hachem, Bjørge Westereng
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
How dietary β-mannans are utilized by gut Gram-positive bacteria is unclear. Here, the authors uncover the enzymatic pathway for β-mannan metabolism in Roseburia intestinalis and show that these polysaccharides promote beneficial gut bacteria, high
Externí odkaz:
https://doaj.org/article/2eb37bf7353c4750bb4b7813444df9b8
Autor:
Hasan Ufuk Celebioglu, Sita Vaag Olesen, Kennie Prehn, Sampo J. Lahtinen, Susanne Brix, Maher Abou Hachem, Birte Svensson
Publikováno v:
Data in Brief, Vol 14, Iss C, Pp 118-122 (2017)
The present study describes the growth of the very well-known probiotic bacterium Lactobacillus acidophilus NCFM on different carbohydrates. Furthermore, recombinant production of putative moonlighting proteins elongation factor G and pyruvate kinase
Externí odkaz:
https://doaj.org/article/0cb3b8af64734a15b247e9738f08fb55
Autor:
Xiaoxiao Li, Yu Wang, Jing Wu, Zhengyu Jin, Lubbert Dijkhuizen, Maher Abou Hachem, Yuxiang Bai
Publikováno v:
Food hydrocolloids, 134:108026. ELSEVIER SCI LTD
Solid-liquid thermo-reversibility, lacking in raw starch is an important property for gels allowing repeated thermal processing in food. In this work, the Thermoproteus uzoniensis 4-α-glucanotransferase (TuαGT) was used to modify five different sta
Autor:
Mia C. Theilmann, Yong Jun Goh, Kristian Fog Nielsen, Todd R. Klaenhammer, Rodolphe Barrangou, Maher Abou Hachem
Publikováno v:
mBio, Vol 8, Iss 6 (2017)
ABSTRACT Therapeutically active glycosylated phytochemicals are ubiquitous in the human diet. The human gut microbiota (HGM) modulates the bioactivities of these compounds, which consequently affect host physiology and microbiota composition. Despite
Externí odkaz:
https://doaj.org/article/c272d79e522f4bdca314091d9e187d49
Autor:
Eva Balaguer Moya, Maria Laura Silva Cunha, Carina Aline Prado, Simone Turella, Silvio Silvério da Silva, Maher Abou-Hachem, Giuliano Dragone, Júlio César dos Santos, Solange Inês Mussatto
Publikováno v:
Catalysts; Volume 12; Issue 10; Pages: 1158
Balaguer Moya, E, Cunha, M L S, Prado, C A, Turella, S, da Silva, S S, Abou-Hachem, M, Dragone, G, dos Santos, J C & Mussatto, S I 2022, ' Evaluation of Enzymatic Hydrolysis of Sugarcane Bagasse Using Combination of Enzymes or Co-Substrate to Boost Lytic Polysaccharide Monooxygenases Action ', Catalysts, vol. 12, no. 10, 1158 . https://doi.org/10.3390/catal12101158
Balaguer Moya, E, Cunha, M L S, Prado, C A, Turella, S, da Silva, S S, Abou-Hachem, M, Dragone, G, dos Santos, J C & Mussatto, S I 2022, ' Evaluation of Enzymatic Hydrolysis of Sugarcane Bagasse Using Combination of Enzymes or Co-Substrate to Boost Lytic Polysaccharide Monooxygenases Action ', Catalysts, vol. 12, no. 10, 1158 . https://doi.org/10.3390/catal12101158
This study evaluated innovative approaches for the enzymatic hydrolysis of lignocellulosic biomass. More specifically, assays were performed to evaluate the supplementation of the commercial cellulolytic cocktail Cellic® CTec2 (CC2) with LPMO (GcLPM