Zobrazeno 1 - 10
of 480
pro vyhledávání: '"Maher, Albitar"'
Publikováno v:
The Journal of Liquid Biopsy, Vol 6, Iss , Pp 100281- (2024)
Background: Cytopathology analysis of cerebrospinal fluid (CSF) is limited in detecting tumors in patients with suspected primary or metastatic central nervous system (CNS) malignancy. We investigated the use of CSF liquid biopsy (LBx) to detect neop
Externí odkaz:
https://doaj.org/article/7abd546b20774102b9e495ab5b56ced6
Autor:
Maher Albitar, Andre Goy, Andrew Pecora, Deena Graham, Donna McNamara, Ahmad Charifa, Andrew IP, Wanlong Ma, Stanley Waintraub
Publikováno v:
ImmunoMedicine, Vol 4, Iss 1, Pp n/a-n/a (2024)
Abstract HER2 and hormone receptors are biomarkers for selecting breast cancer therapy and predicting outcomes. In the era of antibody‐drug conjugates (ADC), a relatively low HER2 expression level is adequate for targeting tumor cells. We explored
Externí odkaz:
https://doaj.org/article/205932e0d42e40cda853f85cf8dc399e
Autor:
Maher Albitar, Hong Zhang, Andrew Pecora, Stanley Waintraub, Deena Graham, Mira Hellmann, Donna McNamara, Ahmad Charifa, Ivan De Dios, Wanlong Ma, Andre Goy
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 17 (2023)
Background: Homologous recombination deficiency (HRD) is the hallmark of breast cancer gene 1/2 ( BRCA1/2 )-mutated tumors and the unique biomarker for predicting response to double-strand break (DSB)–inducing drugs. The demonstration of HRD in tum
Externí odkaz:
https://doaj.org/article/a4b6c138eca440cbb2517f8a68962e5c
Autor:
Maher Albitar, Hong Zhang, Ahmad Charifa, Andrew Ip, Wanlong Ma, James McCloskey, Michele Donato, David Siegel, Stanley Waintraub, Martin Gutierrez, Andrew Pecora, Andre Goy
Publikováno v:
Heliyon, Vol 9, Iss 5, Pp e16261- (2023)
Current use of liquid biopsy is based on cell-free DNA (cfDNA) and the evaluation of mutations or methylation pattern. However, expressed RNA can capture mutations, changes in expression levels due to methylation, and provide information on cell of o
Externí odkaz:
https://doaj.org/article/0a7c0939ee8641638d0e567ca020ccb3
Autor:
Maher Albitar, Hong Zhang, Andre Goy, Zijun Y. Xu-Monette, Govind Bhagat, Carlo Visco, Alexandar Tzankov, Xiaosheng Fang, Feng Zhu, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, Fredrick B. Hagemeister, Jooryung Huh, Maurilio Ponzoni, Andrés J. M. Ferreri, Michael B. Møller, Benjamin M. Parsons, J. Han van Krieken, Miguel A. Piris, Jane N. Winter, Yong Li, Bing Xu, Ken H. Young
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 2, Pp 1-9 (2022)
Abstract Multiple studies have demonstrated that diffuse large B-cell lymphoma (DLBCL) can be divided into subgroups based on their biology; however, these biological subgroups overlap clinically. Using machine learning, we developed an approach to s
Externí odkaz:
https://doaj.org/article/93888a803eda4609ab485bda57596d9c
Autor:
Andrew Ip, Alexandra Della Pia, Gee Youn (Geeny) Kim, Jason Lofters, James Behrmann, Dylon Patel, Simone Kats, Jeffrey Justin Estella, Ivan De Dios, Wanlong Ma, Andrew L. Pecora, Andre H. Goy, Jamie Koprivnikar, James K. McCloskey, Maher Albitar
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionCytogenetic analysis is important for stratifying patients with various neoplasms. We explored the use of targeted next generation sequencing (NGS) in detecting chromosomal structural abnormalities or copy number variations (CNVs) in pati
Externí odkaz:
https://doaj.org/article/841f74756f494596ab6c774a50e1ff13
Publikováno v:
Cancer Treatment and Research Communications, Vol 27, Iss , Pp 100310- (2021)
Purpose: Primary central nervous system lymphoma (PCNSL) is a rare type of non-Hodgkin lymphoma. Previous studies have identified MYD88, CD79b and PIM1 as the most common genetic mutations in PCNSL. The extent to which mutations vary by ethnicity is
Externí odkaz:
https://doaj.org/article/f1c52a48335140b39a7bee87cf942b4a
Autor:
Hua You, Zijun Y. Xu-Monette, Li Wei, Harry Nunns, Máté L. Nagy, Govind Bhagat, Xiaosheng Fang, Feng Zhu, Carlo Visco, Alexandar Tzankov, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, Fredrick B. Hagemeister, Jooryung Huh, Maurilio Ponzoni, Andrés J.M. Ferreri, Michael B. Møller, Benjamin M. Parsons, J. Han Van Krieken, Miguel A. Piris, Jane N. Winter, Yong Li, Qingyan Au, Bing Xu, Maher Albitar, Ken H. Young
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma with high mutation burdens but a low response rate to immune checkpoint inhibitors. In this study, we performed targeted next-generation sequencing and fluorescent multiplex im
Externí odkaz:
https://doaj.org/article/4cc601ce935d46d6bdaa5d24f1fab423
Autor:
Hong Zhang, Muhammad A. Qureshi, Mohsin Wahid, Ahmad Charifa, Aamir Ehsan, Andrew Ip, Ivan De Dios, Wanlong Ma, Ipsa Sharma, James McCloskey, Michele Donato, David Siegel, Martin Gutierrez, Andrew Pecora, Andre Goy, Maher Albitar
Publikováno v:
The American Journal of Pathology. 193:51-59
Diagnosis and classification of tumors is increasingly dependent on biomarkers. RNA expression profiling using next-generation sequencing provides reliable and reproducible information on the biology of cancer. This study investigated targeted transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efcd4eb3701a12fa7db89e89905830f
https://doi.org/10.1016/j.ajpath.2022.09.006
https://doi.org/10.1016/j.ajpath.2022.09.006
Autor:
Alana Vicente, Bhavisha A. Patel, Fernanda Gutierrez-Rodrigues, Emma Groarke, Valentina Giudice, Jennifer Lotter, Xingmin Feng, Sachiko Kajigaya, Barbara Weinstein, Evette Barranta, Matthew J. Olnes, Ankur R. Parikh, Maher Albitar, Colin O. Wu, Ruba Shalhoub, Katherine R. Calvo, Danielle M. Townsley, Phillip Scheinberg, Cynthia E. Dunbar, Neal S. Young, Thomas Winkler
Publikováno v:
Haematologica, Vol 105, Iss 12 (2020)
Myelodysplastic syndromes (MDS) are a group of clonal myeloid disorders characterized by cytopenia and a propensity to develop acute myeloid leukemia (AML). The management of lower-risk (LR) MDS with persistent cytopenias remains suboptimal. Eltrombo
Externí odkaz:
https://doaj.org/article/d39465a6ea80433faa1359329e4d1aed