Zobrazeno 1 - 10
of 378
pro vyhledávání: '"Mahendra S. Rao"'
Autor:
Behnam Ahmadian Baghbaderani, Xinghui Tian, Boon Hwa Neo, Amy Burkall, Tracy Dimezzo, Guadalupe Sierra, Xianmin Zeng, Kim Warren, Don Paul Kovarcik, Thomas Fellner, Mahendra S. Rao
Publikováno v:
Stem Cell Reports, Vol 5, Iss 4, Pp 647-659 (2015)
The discovery of induced pluripotent stem cells (iPSCs) and the concurrent development of protocols for their cell-type-specific differentiation have revolutionized our approach to cell therapy. It has now become critical to address the challenges re
Externí odkaz:
https://doaj.org/article/87a6c61b95c549c695317ba1ea0d7b9d
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
The discovery of reprogramming and generation of human-induced pluripotent stem cells (iPSCs) has revolutionized the field of regenerative medicine and opened new opportunities in cell replacement therapies. While generation of iPSCs represents a sig
Externí odkaz:
https://doaj.org/article/b56ce5d58211405eb37a3072d5bd1b10
Autor:
Hidenori Akutsu, Masakazu Machida, Seiichi Kanzaki, Tohru Sugawara, Takashi Ohkura, Naoko Nakamura, Mayu Yamazaki-Inoue, Takumi Miura, Mohan C. Vemuri, Mahendra S. Rao, Kenji Miyado, Akihiro Umezawa
Publikováno v:
Regenerative Therapy, Vol 1, Iss C, Pp 18-29 (2015)
The potential applications of human embryonic stem cells (hESCs) in regenerative medicine and developmental research have made stem cell biology one of the most fascinating and rapidly expanding fields of biomedicine. The first clinical trial of hESC
Externí odkaz:
https://doaj.org/article/ff9fe3a75f5746b88b5dd394039fb3d7
Autor:
Atossa Shaltouki, Renuka Sivapatham, Ying Pei, Akos A. Gerencser, Olga Momčilović, Mahendra S. Rao, Xianmin Zeng
Publikováno v:
Stem Cell Reports, Vol 4, Iss 5, Pp 847-859 (2015)
In this study, we used patient-specific and isogenic PARK2-induced pluripotent stem cells (iPSCs) to show that mutations in PARK2 alter neuronal proliferation. The percentage of TH+ neurons was decreased in Parkinson’s disease (PD) patient-derived
Externí odkaz:
https://doaj.org/article/09c9b6a82cb84787af6c448a4944fa27
Autor:
Barbara S. Mallon, Rebecca S. Hamilton, Olga A. Kozhich, Kory R. Johnson, Yang C. Fann, Mahendra S. Rao, Pamela G. Robey
Publikováno v:
Stem Cell Research, Vol 12, Iss 2, Pp 376-386 (2014)
Many studies have compared the genetic and epigenetic profiles of human induced pluripotent stem cells (hiPSCs) to human embryonic stem cells (hESCs) and yet the picture remains unclear. To address this, we derived a population of neural precursor ce
Externí odkaz:
https://doaj.org/article/ec43e652c81044fa9c947b8de9a0a1a6
Publikováno v:
Journal of Clinical Medicine, Vol 8, Iss 1, p 117 (2019)
Newborn stem cell banking began with the establishment of cord blood banks more than 25 years ago. Over the course of nearly three decades, there has been considerable evolution in the clinical application of stem cells isolated from newborn tissues.
Externí odkaz:
https://doaj.org/article/219edd08cefb4ad29329b27d352bedeb
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Externí odkaz:
https://doaj.org/article/eafc4dd932f44124b68de3f6eeb142a5
Autor:
A. Shyamsundar, Vivek Benegal, Bangalore N. Gangadhar, Bharath Holla, Mathew Varghese, Ganesan Venkatasubramanian, Pratima Murthy, Sumantra Chattarji, Srinivas Balachander, Odity Mukherjee, Sanjeev Jain, Mahendra S. Rao, Biju Viswanath, Arun Kandasamy, K.G. Vijay Kumar, Palanimuthu T. Sivakumar, Padinjat Raghu, Dhruva Ithal, Jitender Saini, Jayant Mahadevan, Ravi Kumar Nadella, Bhupesh Mehta, Furkhan Ali, John P. John, Jagadisha Thirthalli, Joan C. Puzhakkal, Bhaskarapillai Binukumar, Mitradas M. Panicker, Vanteemar S. Sreeraj, Upinder S. Bhalla, Sydney Moirangthem, Y.C. Janardhan Reddy, Sweta Sheth, Deepak Jayarajan, Meera Purushottam, Naren P. Rao, Kesavan Muralidharan, Thennarasu Kandavel, Urvakhsh Meherwan Mehta
Publikováno v:
Journal of psychiatric research. 142
Background Minor physical anomalies (MPA) are markers of impaired neurodevelopment during the prenatal stage. Assessing MPA across psychiatric disorders may help understand their shared nature. In addition, MPA in family members would indicate a shar
Publikováno v:
Cell and Gene Therapy Insights. 5:203-219
Autor:
Biju Viswanath, Sanjeev Jain, Mahendra S. Rao, Ravi Prabhakar More, Manasa Seshadri, Ahmed P H, Ravi Kumar Nadella, Suhas Ganesh, Odity Mukherjee
Publikováno v:
Psychiatry and Clinical Neurosciences
IntroductionSevere Mental Illnesses (SMI), such as bipolar disorder and schizophrenia, are highly heritable, and have a complex pattern of inheritance. Genome wide association studies detect a part of the heritability, which can be attributed to comm