Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Mahendra Pal Singh"'
Autor:
Monika Bhardwaj, Jennifer J. Lee, Amanda M. Versace, Sandra L. Harper, Aaron R. Goldman, Mary Ann S. Crissey, Vaibhav Jain, Mahendra Pal Singh, Megane Vernon, Andrew E. Aplin, Seokwoo Lee, Masao Morita, Jeffrey D. Winkler, Qin Liu, David W. Speicher, Ravi K. Amaravadi
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 8 (2023)
Lysosomal inhibition elicited by palmitoyl-protein thioesterase 1 (PPT1) inhibitors such as DC661 can produce cell death, but the mechanism for this is not completely understood. Programmed cell death pathways (autophagy, apoptosis, necroptosis, ferr
Externí odkaz:
https://doaj.org/article/fad0eadd0ff64a57986f4c0b83cbe4f7
Autor:
Ravishankar Ramachandran, Vivek Bhosale, Himanshu Reddy, Virendra Atam, MMA Faridi, Jalees Fatima, Vaibhav Shukla, Zaw A Khan, Hana Khan, Vikram Singh, Mahendra Pal Singh Negi, Mukesh Srivastava, Ajay Kumar Srivastava, Chandra Bhushan Tripathi, Nayan Ghosh, Nilanjana Majumdar, Raj Kamal Tripathi, Srikanta Kumar Rath, Prabhat Ranjan Mishra, Sharad Sharma, Tapas K Kundu
Publikováno v:
International Journal of Infectious Diseases, Vol 115, Iss , Pp 62-69 (2022)
Objective: To test efficacy, safety and tolerability of Umifenovir in non-severe COVID-19 adult patients. Methods: We carried out randomized, double-blind, placebo-controlled, multicenter, phase III trials involving adult (18-75 years), non-severe CO
Externí odkaz:
https://doaj.org/article/dcd93c210c8347afac38aa1f14db76ae
Autor:
Sadashiv, Anupama Modi, Manoj Khokhar, Praveen Sharma, Rajnish Joshi, Sudhanshu Shekhar Mishra, Rajay N Bharshankar, Sunita Tiwari, Pankaj Kumar Singh, Vivek Vidyadhar Bhosale, Mahendra Pal Singh Negi
Publikováno v:
Journal of Obesity & Metabolic Syndrome, Vol 30, Iss 3, Pp 304-311 (2021)
Background : It is well established that obesity is a major health risk in diabetes and associated diseases. Epigenetic changes, specially DNA methylation, play an important role in regulation of adipokines. The objective of the present study was to
Externí odkaz:
https://doaj.org/article/f7f4fe609f1f4bd0be75148bc9d06953
Publikováno v:
Cancer Medicine, Vol 10, Iss 15, Pp 5175-5190 (2021)
Abstract Background Anatomical variations in head and neck cancer during IMRT leads to volume shrinkage, results in dosimetric variations in tumour and normal tissue including parotid glands, with a risk of radiation toxicities. Methods 30 patients w
Externí odkaz:
https://doaj.org/article/6717ddc447274db0a5ae22438efbb934
Autor:
Yujiro Hayashi, David T. Asuzu, Michael R. Bardsley, Gabriella B. Gajdos, Sergiy M. Kvasha, David R. Linden, Rea A. Nagy, Siva Arumugam Saravanaperumal, Sabriya A. Syed, Yoshitaka Toyomasu, Huihuang Yan, Eduardo N. Chini, Simon J. Gibbons, Todd A. Kellogg, Khashayarsha Khazaie, Makoto Kuro-o, Jair Machado Espindola Netto, Mahendra Pal Singh, James G. Tidball, Michelle Wehling-Henricks, Gianrico Farrugia, Tamas Ordog
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 117-145 (2021)
Background & Aims: Gastric dysfunction in the elderly may cause reduced food intake, frailty, and increased mortality. The pacemaker and neuromodulator cells interstitial cells of Cajal (ICC) decline with age in humans, and their loss contributes to
Externí odkaz:
https://doaj.org/article/8b43f8672b2b4107aadaf0a158051895
Autor:
Shreyash Rai, Pankaj Kumar Garg, Shuchi Bhatt, Thammineni Krishna Latha, Amit Kumar Verma, Basu Dev Banerjee, Mahendra Pal Singh
Publikováno v:
Lung India, Vol 37, Iss 6, Pp 501-505 (2020)
Background: Although histopathological examination of the biopsy specimen is the gold standard for the diagnosis of non small cell lung cancer (NSCLC), a blood-based noninvasive test (liquid biopsy) may prove to be helpful in patients with repeatedly
Externí odkaz:
https://doaj.org/article/fc65fe1f6a7e4ddca2d24be92efba859
Publikováno v:
Reproductive Biology and Endocrinology, Vol 16, Iss 1, Pp 1-9 (2018)
Abstract Background Since the first report of a decline in semen quality in 1974, there have been several reports of similar declines across populations. Despite some scattered reports of declining semen quality in the Indian sub-continent, comprehen
Externí odkaz:
https://doaj.org/article/4d883d11127542d6a365ddbb78c5bf1f
Autor:
Abdulrahman Saadalla, Mariana Machado Lima, Funien Tsai, Abu Osman, Mahendra Pal Singh, David R. Linden, Kristen L. Dennis, S. M. Mansour Haeryfar, Michael F. Gurish, Fotini Gounari, Khashayarsha Khazaie
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Mast cells constitutively express ß-catenin and expand in solid tumors such as colon and skin cancer. However, the role of ß-catenin signaling in mast cells and the cause or effect of mast cell expansion and tumor growth has yet to be established.
Externí odkaz:
https://doaj.org/article/d74f0c3cead74cfbad7b4ed8559236bf
Autor:
Mahendra Pal Singh, Tejinder Pal Khaket, Vivek K. Bajpai, Saleh Alfarraj, Se-Gie Kim, Lei Chen, Yun Suk Huh, Young-Kyu Han, Sun Chul Kang
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8253 (2020)
The cross-talk between apoptosis and autophagy influences anticancer drug sensitivity and cellular death in various cancer cell lines. However, the fundamental mechanisms behind this phenomenon are still unidentified. We demonstrated anti-cancerous r
Externí odkaz:
https://doaj.org/article/a0d1f917244d4e4c96d025e65bf35f77
Autor:
Seema Gupta, Vandana Singh Kushwaha, Sandeep Verma, Huma Khan, M.L.B. Bhatt, Nuzhat Husain, Mahendra Pal Singh Negi, Vivek Vidyadhar Bhosale, Ashim Ghatak
Publikováno v:
Heliyon, Vol 2, Iss 12 (2016)
Introduction: Oral cancer accounts for approximately 2.1% of all cancers worldwide. In India, oral squamous cell carcinoma (OSCC) is the most common cancer with half a million new cases diagnosed every year. More than 50% of patients eventually devel
Externí odkaz:
https://doaj.org/article/0393deaa580d4ed1842b1baa61e81e09