Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Mahendra P. Darokar"'
Autor:
Saurabh Kumar, Deepak Singh kapkoti, Pooja Rani Mina, Divya Bhatt, Parmanand Kumar, Manju Singh, Karuna Shanker, Dnyaneshwar Umrao Bawankule, Rajendra Singh Bhakuni, Anirban Pal, Mahendra P. Darokar
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 10, Iss , Pp 100396- (2024)
Introduction: Malaria control is hindered by drug-resistant parasites, leading to a shortage of effective drugs. There is a need to find new, better antimalarial drug. Traditional Chinese Medicine (TCM) are more accessible and cheaper alternative for
Externí odkaz:
https://doaj.org/article/bc30bc5e9029446389a8378f0bdf4fc4
Publikováno v:
Drugs and Drug Candidates, Vol 2, Iss 2, Pp 295-310 (2023)
Acquired bacterial resistance against several antibiotics has severely impaired the drug treatment regime. Multidrug-resistant Staphylococcus aureus (MDRSA) causes several life-threatening human pathologies. The introduction of novel antibiotics is a
Externí odkaz:
https://doaj.org/article/d90a1783b35f4b8c92418e2721f6011d
Autor:
Sneha Sinha, Vivek Kumar Gupta, Parmanand Kumar, Rajiv Kumar, Robin Joshi, Anirban Pal, Mahendra P. Darokar
Publikováno v:
FEBS Open Bio, Vol 9, Iss 12, Pp 2025-2040 (2019)
Multidrug‐resistant Staphylococcus aureus infections place a huge burden on the healthcare sector and the wider community. An increasing rate of infections caused by methicillin‐resistant Staphylococcus aureus (MRSA) has necessitated the developm
Externí odkaz:
https://doaj.org/article/132689f955be4646ba608ed0b570e059
Autor:
Gaurav Raj Dwivedi, Reeta Rai, Ramendra Pratap, Khusbu Singh, Sanghamitra Pati, Satya Narayan Sahu, Rajni Kant, Mahendra P. Darokar, Dharmendra K. Yadav
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 142, Iss , Pp 112084- (2021)
We explored the antibacterial potential (alone and combination) against multidrug resistant (MDR) Pseudomonas aeruginosa isolates KG-P2 using synthesized thieno[3,2-c]pyran-2-ones in combination with different antibiotics. Out of 14 compounds, two co
Externí odkaz:
https://doaj.org/article/70153e65d96348268e6a753366831119
Autor:
Pooja Rani Mina, Saurabh Kumar, Karishma Agarwal, Ravi Kumar, Anirban Pal, Sudeep Tandon, Sanjeev Kumar Yadav, Sanjay Yadav, Mahendra P. Darokar
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 137, Iss , Pp 111311- (2021)
4-chloro eugenol (4CE), a semisynthetic analog of phytomolecule eugenol exhibited potent antiplasmodial activity with IC50 in the range of 1.5–5 μM against sensitive as well as drug resistant strain of P. falciparum. This analog also showed synerg
Externí odkaz:
https://doaj.org/article/233b82434a0a4563a371806a204232d7
4-Chlorothymol Exerts Antiplasmodial Activity Impeding Redox Defense System in Plasmodium falciparum
Autor:
Saurabh Kumar, Pooja Rani Mina, Ravi Kumar, Anirban Pal, Ateeque Ahmad, Sudeep Tandon, Mahendra P. Darokar
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Malaria remains one of the major health concerns due to the resistance of Plasmodium species toward the existing drugs warranting an urgent need for new antimalarials. Thymol derivatives were known to exhibit enhanced antimicrobial activities; howeve
Externí odkaz:
https://doaj.org/article/792369d9fa6b4a6f863daf43712ce0cd
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Staphylococcus aureus is an opportunistic bacterium of the human body and a leading cause of nosocomial infections. Methicillin resistant S. aureus (MRSA) infections involving biofilm lead to higher mortality and morbidity in patients. Biofilm causes
Externí odkaz:
https://doaj.org/article/3b6f4f772fc442829d01b52321091b10
Autor:
Priyanka Sharma, Priyanka Pathak, Vidushi Tyagi, Feroz Khan, Karuna Shanker, Mahendra Pandurang Darokar, Anirban Pal
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Vitamin B12 deficiency is prevalent among individuals globally. Inadequate consumption of B12 rich diet and low bioavailability (due to diet based/physiological factors) are linked to the deficiency of Vitamin B12 inside the body. Bioavailability enh
Externí odkaz:
https://doaj.org/article/66a60737ad854811a560a72eca4b14ce
Autor:
Deepak Singh Kapkoti, Saurabh Kumar, Ashish Kumar, Mahendra P. Darokar, Anirban Pal, Rajendra Singh Bhakuni
Publikováno v:
New Journal of Chemistry. 47:6967-6982
Malaria is an enormous threat to public health due to the emergence of Plasmodium falciparum resistance to widely used anti-malarials, such as chloroquine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a5c5f855be64af1006989ee37397dd8
https://doi.org/10.1039/d2nj05302k
https://doi.org/10.1039/d2nj05302k
Autor:
Saurabh Kumar, Deepak Singh Kapkoti, Pooja Rani Mina, Madhuri Gupta, Ravi Kumar, Parmanand Kumar, Priyanka Pathak, R S Bhakuni, Prasant Rout, Anirban Pal, Mahendra P. Darokar
Publikováno v:
Phytomedicine. 114:154738
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7955a197e9d41b2e32a14ca29f7e3f74
https://doi.org/10.1016/j.phymed.2023.154738
https://doi.org/10.1016/j.phymed.2023.154738