Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Maheleth Llinas"'
Autor:
Agessandro Abrahao, Ying Meng, Maheleth Llinas, Yuexi Huang, Clement Hamani, Todd Mainprize, Isabelle Aubert, Chinthaka Heyn, Sandra E. Black, Kullervo Hynynen, Nir Lipsman, Lorne Zinman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
MR-focused ultrasound can be used to transiently open the blood-brain barrier (BBB). Here, the authors report the results of a first-in-human trial on four patients with amyotrophic lateral sclerosis (ALS), showing that the procedure reversibly perme
Externí odkaz:
https://doaj.org/article/39152bb20d4547b38efa39b5f3872500
Autor:
Walter Kucharczyk, Gavin J B Elias, Alfonso Fasano, Clement Hamani, Suresh Joel, Alexandre Boutet, Andres M. Lozano, Philippe De Vloo, Robert Gramer, Maheleth Llinas
Publikováno v:
Journal of Neurosurgery. 136:215-220
Dysgeusia, or distorted taste, has recently been acknowledged as a complication of thalamic ablation or thalamic deep brain stimulation as a treatment of tremor. In a unique patient, left-sided MR-guided focused ultrasound thalamotomy improved right-
Autor:
Ying Meng, Julia Keith, Hon S. Leong, Arun Seth, Yuexi Huang, Kullervo Hynynen, Arjun Sahgal, Chinthaka Heyn, Nir Lipsman, Christopher B Pople, Suganth Suppiah, Maheleth Llinas, Isabelle Aubert, James Perry, Benjamin Davidson, Clement Hamani, Yutaka Amemiya
Publikováno v:
Neuro-Oncology
Background Liquid biopsy is promising for early detection, monitoring of response, and recurrence of cancer. The blood-brain barrier (BBB) limits the shedding of biomarker, such as cell-free DNA (cfDNA), into the blood from brain tumors, and their de
Autor:
James Perry, Ying Meng, Rossanna C. Pezo, Sten Myrehaug, Clement Hamani, Chinthaka Hyen, Arjun Sahgal, Benjamin Davidson, Raymond M. Reilly, Yuexi Huang, Suganth Suppiah, Amit Singnurkar, Nir Lipsman, Maheleth Llinas, Kullervo Hynynen, Christopher B Pople, Maureen E. Trudeau
Publikováno v:
Science translational medicine. 13(615)
The blood-brain barrier (BBB) is an important factor limiting the effectiveness of central nervous system (CNS) therapeutics. MR-guided focused ultrasound (MRgFUS) is a noninvasive, spatially precise technology that enhances drug delivery across a te
Autor:
Alexandre Boutet, Andres M. Lozano, Mojgan Hodaie, Ailish Coblentz, Kullervo Hynynen, Eugen Hlasny, Gabriel A. Devenyi, Walter Kucharczyk, Christopher S Lozano, Gavin J B Elias, Maheleth Llinas, Alfonso Fasano, Jidan Zhong, Jason R. Chan, David S. Xu, M. Mallar Chakravarty, Nir Lipsman, Jürgen Germann, Michael L. Schwartz, Manish Ranjan
Publikováno v:
Brain. 141:3405-3414
Magnetic resonance guided focused ultrasound (MRgFUS) thalamotomy is a novel and minimally invasive ablative treatment for essential tremor. The size and location of therapeutic lesions producing the optimal clinical benefits while minimizing adverse
Autor:
Ying Meng, Agessandro Abrahao, Todd G. Mainprize, Clement Hamani, Sandra E. Black, Kullervo Hynynen, Lorne Zinman, Isabelle Aubert, Chinthaka Heyn, Yuexi Huang, Maheleth Llinas, Nir Lipsman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Nature Communications
Nature Communications
MR-guided focused ultrasound (MRgFUS) is an emerging technology that can accurately and transiently permeabilize the blood-brain barrier (BBB) for targeted drug delivery to the central nervous system. We conducted a single-arm, first-in-human trial t
Autor:
Ying, Meng, Benjamin, Solomon, Alexandre, Boutet, Maheleth, Llinas, Nadia, Scantlebury, Yuexi, Huang, Kullervo, Hynynen, Clement, Hamani, Alfonso, Fasano, Andres M, Lozano, Nir, Lipsman, Michael L, Schwartz
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 33(10)
Magnetic resonance-guided focused ultrasound is an emerging, minimally invasive thermoablation technique for medically refractory essential tremor. Beyond the initial year, data regarding efficacy and potential predictors of efficacy are still prelim
Autor:
Gaddum Duemani Reddy, Alfonso Fasano, Darcia Paul, Nathan C. Rowland, Brian J. Murray, Renato P. Munhoz, Francesco Sammartino, Philippe De Vloo, Maheleth Llinas, Suneil K. Kalia, Anthony E. Lang
Publikováno v:
Movement Disorders. 34:585-586
Publikováno v:
Neurology. 87:736-738
MRI-guided focused ultrasound (MRgFUS) is a promising, incision-free but nevertheless invasive technique to ablate deep brain targets.1 Recent studies have investigated the effectiveness and safety of MRgFUS targeting the ventrointermedius nucleus (V
Autor:
Andres M. Lozano, Eugen Hlasny, Renato P. Munhoz, Alfonso Fasano, Walter Kucharczyk, Maheleth Llinas
Publikováno v:
Neurology. 89(8)
Objective:To report the 6-month single-blinded results of unilateral thalamotomy with MRI-guided focused ultrasound (MRgFUS) in patients with tremors other than essential tremor.Methods:Three patients with tremor due to Parkinson disease, 2 with dyst