Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Maheedhara R, Guda"'
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-13 (2022)
Abstract Galectins are a family of β-galactose-specific binding proteins residing within the cytosol or nucleus, with a highly conserved carbohydrate recognition domain across many species. Accumulating evidence shows that Galectin 1 (Gal-1) plays a
Externí odkaz:
https://doaj.org/article/b3c3f0327b2848dcb476d301a94f27cd
Autor:
Swapna Asuthkar, Sujatha Venkataraman, Janardhan Avilala, Katherine Shishido, Rajeev Vibhakar, Bethany Veo, Ian J. Purvis, Maheedhara R. Guda, Kiran K. Velpula
Publikováno v:
Cancers, Vol 14, Iss 7, p 1673 (2022)
Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Maximum safe resection, postoperative craniospinal irradiation, and chemotherapy are the standard of care for MB patients. MB is classified into four subgroups: Shh, Wnt, Group
Externí odkaz:
https://doaj.org/article/1e66e13782234ef798f89d1b9d81c601
Publikováno v:
F1000Research, Vol 9 (2020)
The pandemic brought on by the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has become a global health crisis, with over 22 million confirmed cases and 777,000 fatalities due to coronavirus disease 2019 (COVID-19) reported
Externí odkaz:
https://doaj.org/article/b0204a9be64344c48e547ba0ba44c16b
Publikováno v:
PeerJ, Vol 8, p e9392 (2020)
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), the causative agent of coronavirus disease 2019 (COVID-19), has been declared a global pandemic by the World Health Organization. With no standard of care for the treatment
Externí odkaz:
https://doaj.org/article/23debeb1c7ed4d8ebf48a170495642fc
Autor:
Willie Elliott, Maheedhara R. Guda, Swapna Asuthkar, Narasaraju Teluguakula, Durbaka V. R. Prasad, Andrew J. Tsung, Kiran K. Velpula
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1867 (2021)
Since the discovery of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019, the virus’s dynamicity has resulted in the evolution of various variants, including the delta variant and the more novel mu variant. With a multit
Externí odkaz:
https://doaj.org/article/e4a158bbfe6d465090f8eb42e37875ac
Autor:
Ian J. Purvis, Kiran K. Velpula, Maheedhara R. Guda, Daniel Nguyen, Andrew J. Tsung, Swapna Asuthkar
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7050 (2020)
(1) Aim: Medulloblastoma is the most common aggressive pediatric cancer of the central nervous system. Improved therapies are necessary to improve life outcomes for medulloblastoma patients. Exosomes are a subset of extracellular vesicles that are ex
Externí odkaz:
https://doaj.org/article/7097f1d00d544cfb80ff21aebeb2c0a5
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3300 (2020)
Glioblastoma (GBM) is the most common type of adult primary brain tumor with a median survival rate of less than 15 months, regardless of the current standard of care. Cellular heterogeneity, self-renewal ability and tumorigenic glioma cancer stem ce
Externí odkaz:
https://doaj.org/article/85fa6f0ac1b644f9abb9121440c7dede
Autor:
Maheedhara R. Guda, Collin M. Labak, Sara Ibrahim Omar, Swapna Asuthkar, Subra Airala, Jack Tuszynski, Andrew J. Tsung, Kiran K. Velpula
Publikováno v:
Cancers, Vol 11, Iss 9, p 1308 (2019)
Glioblastoma multiforme (GBM) is the most aggressive and deadly brain tumor, portending a median 13-month survival even following gross total resection with adjuvant chemotherapy and radiotherapy. This prognosis necessitates improved therapies for th
Externí odkaz:
https://doaj.org/article/1d2182cb8ffc4bafbacd8874fa9a074b
Autor:
Ian J. Purvis, Janardhan Avilala, Maheedhara R. Guda, Sujatha Venkataraman, Rajeev Vibhakar, Andrew J. Tsung, Kiran K. Velpula, Swapna Asuthkar
Publikováno v:
Journal of Clinical Medicine, Vol 8, Iss 8, p 1158 (2019)
Medulloblastoma (MB) is the most common embryonal neuroepithelial tumor, with poor patient outcomes and secondary complications. In this study, we investigated the role of the B7 family of immune checkpoint homolog 3 (B7-H3) expression in MB angiogen
Externí odkaz:
https://doaj.org/article/476e91cf89554cc686e016616abce20a
Autor:
Anvesh, Jalasutram, John L, Caniglia, Kiran K, Velpula, Maheedhara R, Guda, Sarah E, Bach, Andrew J, Tsung
Publikováno v:
Am J Transl Res
The molecular mechanisms underlying progression from astrocytoma to secondary glioblastoma are poorly understood. Telomerase reverse transcriptase (TERT), a gene encoding for the catalytic subunit of telomerase, is upregulated in various cancers. Upr