Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Mahdis, Monajemi"'
Autor:
Sarah J. Colpitts, Matthew A. Budd, Mahdis Monajemi, Kyle T. Reid, Julia M. Murphy, Sabine Ivison, C. Bruce Verchere, Megan K. Levings, Sarah Q. Crome
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Defining the immunological landscape of human tissue is an important area of research, but challenges include the impact of tissue disaggregation on cell phenotypes and the low abundance of immune cells in many tissues. Here, we describe methods to t
Externí odkaz:
https://doaj.org/article/a3403a527ce5473e87c809b9fafea3b5
Autor:
Chi-Chao Liu, Pascal Leclair, Foujan Pedari, Heidi Vieira, Mahdis Monajemi, Laura M. Sly, Gregor S. Reid, Chinten James Lim
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Therapy-induced presentation of cell surface calreticulin (CRT) is a pro-phagocytic immunogen beneficial for invoking anti-tumor immunity. Here, we characterized the roles of ERp57 and α-integrins as CRT-interacting proteins that coordinately regula
Externí odkaz:
https://doaj.org/article/aec8cc951b8744268b6cb660dd7df2f2
Autor:
Sarah J. Colpitts, Matthew A Budd, Sarah Q. Crome, Megan K. Levings, Mahdis Monajemi, C. Bruce Verchere
Publikováno v:
Diabetologia. 64:2378-2388
Type 1 diabetes results from defects in immune self-tolerance that lead to inflammatory infiltrate in pancreatic islets, beta cell dysfunction and T cell-mediated killing of beta cells. Although therapies that broadly inhibit immunity show promise to
Autor:
Caigan Du, Haiming D. Luo, Megan K. Levings, Christine M. Wardell, Kevin Rey, Jayachandran N. Kizhakkedathu, Lyann Sim, Jonathan C. Choy, Qiunong Guan, Stephen G. Withers, Zheng J. Zhang, Franklin Tam, Mahdis Monajemi, Haisle Moon, Majid Mojibian, Ashani Montgomery, Erika M. J. Siren, Winnie Enns, Jiao Jing Wang
Publikováno v:
Nature Biomedical Engineering. 5:1202-1216
Systemic immunosuppression for the mitigation of immune rejection after organ transplantation causes adverse side effects and constrains the long-term benefits of the transplanted graft. Here we show that protecting the endothelial glycocalyx in vasc
Autor:
Susan C. Menzies, Jessica Leung, Mahdis Monajemi, Rym Ben-Othman, Tobias R. Kollmann, Laura M. Sly, Bing Cai, Shera Fisk, Yvonne C. F. Pang, Jacob Rozmus
Publikováno v:
Journal of Leukocyte Biology. 106:863-877
This study tested the hypothesis that mucosa associated lymphoid tissue 1 (Malt1) deficiency causes osteoporosis in mice by increasing osteoclastogenesis and osteoclast activity. A patient with combined immunodeficiency (CID) caused by MALT1 deficien
Autor:
Mahdis Monajemi, Claire F Woodworth, Katrin Zipperlen, Maureen Gallant, Michael D Grant, Mani Larijani
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93428 (2014)
Due to constitutive expression in cells targeted by human immunodeficiency virus (HIV), and immediate mode of viral restriction upon HIV entry into the host cell, APOBEC3G (A3G) and APOBEC3F (A3F) have been considered primarily as agents of innate im
Externí odkaz:
https://doaj.org/article/f7d377f606264b15884137f88a126b5b
Autor:
Matthew A, Budd, Mahdis, Monajemi, Sarah J, Colpitts, Sarah Q, Crome, C Bruce, Verchere, Megan K, Levings
Publikováno v:
Diabetologia. 64(11)
Type 1 diabetes results from defects in immune self-tolerance that lead to inflammatory infiltrate in pancreatic islets, beta cell dysfunction and T cell-mediated killing of beta cells. Although therapies that broadly inhibit immunity show promise to
Autor:
Erika M J, Siren, Haiming D, Luo, Franklin, Tam, Ashani, Montgomery, Winnie, Enns, Haisle, Moon, Lyann, Sim, Kevin, Rey, Qiunong, Guan, Jiao-Jing, Wang, Christine M, Wardell, Mahdis, Monajemi, Majid, Mojibian, Megan K, Levings, Zheng J, Zhang, Caigan, Du, Stephen G, Withers, Jonathan C, Choy, Jayachandran N, Kizhakkedathu
Publikováno v:
Nature biomedical engineering. 5(10)
Systemic immunosuppression for the mitigation of immune rejection after organ transplantation causes adverse side effects and constrains the long-term benefits of the transplanted graft. Here we show that protecting the endothelial glycocalyx in vasc
Autor:
Chi-Chao Liu, Gregor S. D. Reid, Chinten James Lim, Pascal Leclair, Laura M. Sly, Mahdis Monajemi
Publikováno v:
Cell Death and Disease, Vol 9, Iss 5, Pp 1-14 (2018)
Cell Death & Disease
Cell Death & Disease
CD47 is a cell-surface marker well recognized for its anti-phagocytic functions. As such, an emerging avenue for targeted cancer therapies involves neutralizing the anti-phagocytic function using monoclonal antibodies (mAbs) to enhance tumour cell im
Autor:
Nico van Rooijen, Mahdis Monajemi, Susan C. Menzies, Saelin Bjornson, Yvonne C. F. Pang, Laura M. Sly
Publikováno v:
Journal of leukocyte biology. 104(3)
This study tested the hypothesis that Malt1 deficiency in macrophages contributes to dextran sodium sulfate (DSS)-induced intestinal inflammation in Malt1-deficient mice. In people, combined immunodeficiency caused by a homozygous mutation in the MAL