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Akademický článek

Molecular docking and mouse modeling suggest CMKLR1 and INSR as targets for improving PCOS phenotypes by minocycline

Autor: Mahdie Kian, Elham Hosseini, Tooba Abdizadeh, Taimour Langaee, Azadeh Khajouei, Sorayya Ghasemi

Publikováno v: EXCLI Journal : Experimental and Clinical Sciences, Vol 21, Pp 400-414 (2022)

Polycystic ovary syndrome (PCOS) is the most common cause of women’s infertility. Some inflammatory pathways play a pivotal role in the pathogenesis of PCOS. This study aimed to investigate the possible beneficial effects of minocycline on chemokin

Externí odkaz: https://doaj.org/article/0007b20517ee4536827095b921d9adf4

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Beneficial effects of minocycline on the ovary of polycystic ovary syndrome mouse model: Molecular docking analysis and evaluation of TNF-α, TNFR2, TLR-4 gene expression

Autor: Mahdie Kian, Sorayya Ghasemi, Azadeh Khajouei, Tooba Abdizadeh, Elham Hosseini

Publikováno v: Journal of Reproductive Immunology. 144:103289

Polycystic ovary syndrome (PCOS) is the most common cause of ovulatory infertility. Inflammation may be involved in the pathogenesis and development of PCOS. We investigated the anti-inflammatory effect of minocycline on TNF-α, TNFR2, and TLR4 expre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142d62f13384cc12abb90201f7c074c0
https://doi.org/10.1016/j.jri.2021.103289

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