Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mahdi Moqri"'
Autor:
Kejun Ying, José P. Castro, Anastasia V. Shindyapina, Alexander Tyshkovskiy, Mahdi Moqri, Ludger J. E. Goeminne, Sofiya Milman, Zhengdong D. Zhang, Nir Barzilai, Vadim N. Gladyshev
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract While previous studies identified common genetic variants associated with longevity in centenarians, the role of the rare loss-of-function (LOF) mutation burden remains largely unexplored. Here, we investigated the burden of rare LOF mutatio
Externí odkaz:
https://doaj.org/article/5caa0089e32b4109a566c31b600051c0
Autor:
Andrea Cipriano, Alessio Colantoni, Alessandro Calicchio, Jonathan Fiorentino, Danielle Gomes, Mahdi Moqri, Alexander Parker, Sajede Rasouli, Matthew Caldwell, Francesca Briganti, Maria Grazia Roncarolo, Antonio Baldini, Katja G. Weinacht, Gian Gaetano Tartaglia, Vittorio Sebastiano
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-39 (2024)
Abstract Background The Pharyngeal Endoderm (PE) is an extremely relevant developmental tissue, serving as the progenitor for the esophagus, parathyroids, thyroids, lungs, and thymus. While several studies have highlighted the importance of PE cells,
Externí odkaz:
https://doaj.org/article/f51958fa58764091b1141540dff228c9
Autor:
Mahdi Moqri, Andrea Cipriano, Daniel J. Simpson, Sajede Rasouli, Tara Murty, Tineke Anna de Jong, Daniel Nachun, Guilherme de Sena Brandine, Kejun Ying, Andrei Tarkhov, Karolina A. Aberg, Edwin van den Oord, Wanding Zhou, Andrew Smith, Crystal Mackall, Vadim N. Gladyshev, Steve Horvath, Michael P. Snyder, Vittorio Sebastiano
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract DNA methylation (DNAm) is one of the most reliable biomarkers of aging across mammalian tissues. While the age-dependent global loss of DNAm has been well characterized, DNAm gain is less characterized. Studies have demonstrated that CpGs wh
Externí odkaz:
https://doaj.org/article/903dd1a324284990bb38ba6fe77d4c37
Autor:
Nima Safaei, Babak Safaei, Seyedhouman Seyedekrami, Mojtaba Talafidaryani, Arezoo Masoud, Shaodong Wang, Qing Li, Mahdi Moqri
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0262895 (2022)
Improving the Intensive Care Unit (ICU) management network and building cost-effective and well-managed healthcare systems are high priorities for healthcare units. Creating accurate and explainable mortality prediction models helps identify the most
Externí odkaz:
https://doaj.org/article/fe12bfcb76e243b7b514628bf474b315
Autor:
Kejun Ying, Alexander Tyshkovskiy, Alexandre Trapp, Hanna Liu, Mahdi Moqri, Csaba Kerepesi, Vadim N. Gladyshev
Aging represents the greatest risk factor for chronic diseases and mortality, but to understand it we need the ability to measure biological age. In recent years, many machine learning algorithms based on omics data, termed aging clocks, have been de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::790cdb00ea3f43518903309ef396cc8c
https://doi.org/10.1101/2023.02.28.530532
https://doi.org/10.1101/2023.02.28.530532
Autor:
Mahdi Moqri, Michael Snyder
Publikováno v:
Nature Medicine. 29:1068-1069
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33b7de681f134bd81e4319d33e6c1a82
https://doi.org/10.1038/s41591-023-02338-z
https://doi.org/10.1038/s41591-023-02338-z
Autor:
Andrei E. Tarkhov, Thomas Lindstrom-Vautrin, Sirui Zhang, Kejun Ying, Mahdi Moqri, Bohan Zhang, Vadim N. Gladyshev
Age-related changes in DNA methylation (DNAm) form the basis for the development of most robust predictors of age, epigenetic clocks, but a clear mechanistic basis for what exactly they quantify is lacking. Here, to clarify the nature of epigenetic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3f950e94bbe74459efac10e500bbcb7
https://doi.org/10.1101/2022.09.26.509592
https://doi.org/10.1101/2022.09.26.509592
Autor:
Mahdi Moqri, Andrea Cipriano, Daniel Nachun, Tara Murty, Guilherme de Sena Brandine, Sajede Rasouli, Andrei Tarkhov, Karolina A. Aberg, Edwin van den Oord, Wanding Zhou, Andrew Smith, Crystal Mackall, Vadim Gladyshev, Steve Horvath, Michael P. Snyder, Vittorio Sebastiano
DNA methylation (DNAm) is one of the most reliable biomarkers for aging across many mammalian tissues. While the age-dependent global loss of DNAm has been well characterized, age-dependent DNAm gain is less specified. Multiple studies have demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::510debb68f4612d737de50ef6623717d
https://doi.org/10.1101/2022.06.03.494609
https://doi.org/10.1101/2022.06.03.494609
Autor:
Javad Norouzi Nia, Atousa Zarindast, Masoud Salehi, Fateme Fotouhi, Mahdi Moqri, Nima Safaei, Reyhaneh Bijari, Atefeh Rajabalizadeh, Mojtaba Talafidaryani
The monitoring of severely ill patients is a crucial procedure for every intensive care unit (ICU). By applying different data exploration methods on monitoring data, some perspective can be gained. In the present research, such monitoring data were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b491f399e550b033cd7263df0be9bf3
https://doi.org/10.1101/2020.03.29.20042028
https://doi.org/10.1101/2020.03.29.20042028
Publikováno v:
Journal of Management Information Systems. 35:1188-1217
In this study, we estimate the effect of “online following,” a basic form of online social interaction, on members’ contributions in open source software (OSS) communities, using a unique longitudinal data set containing information on over 4 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38453f1d63f70cd7c203ae6a9a08c9d4
https://doi.org/10.1080/07421222.2018.1523605
https://doi.org/10.1080/07421222.2018.1523605