Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mahdi Hijazi"'
Autor:
Robert E. Jefferson, Aurélien Oggier, Andreas Füglistaler, Nicolas Camviel, Mahdi Hijazi, Ana Rico Villarreal, Caroline Arber, Patrick Barth
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Engineering protein biosensors that sensitively respond to specific biomolecules by triggering precise cellular responses is a major goal of diagnostics and synthetic cell biology. Previous biosensor designs have largely relied on binding st
Externí odkaz:
https://doaj.org/article/6b49ba1051634d6fb46147418a7f26b1
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Following the hugely successful application of deep learning methods to protein structure prediction, an increasing number of design methods seek to leverage generative models to design proteins with improved functionality over native proteins or nov
Externí odkaz:
https://doaj.org/article/ac0fb84c216840fa8c3e443a026d9a7e
Autor:
Roger K. Sunahara, Mahdi Hijazi, Patrick Barth, Punita Kumari, Xiao Chen Bai, Mary J. Clark, Jie Yin, Daniel M. Rosenbaum, Kuang Yui M. Chen
Publikováno v:
Nature
The D2 dopamine receptor (DRD2) is a therapeutic target for Parkinson's disease1 and antipsychotic drugs2. DRD2 is activated by the endogenous neurotransmitter dopamine and synthetic agonist drugs such as bromocriptine3, leading to stimulation of Gi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad5aa04b7d121910a64e1b355196ef4
https://doi.org/10.1038/s41586-020-2379-5
https://doi.org/10.1038/s41586-020-2379-5
Publikováno v:
IBM Journal of Research and Development. 62:5:1-5:9
The design and development of novel drugs could benefit considerably from more reliable atomistic modeling schemes able to deal with the appropriate level of theoretical description on size and time scales relevant for complex life-science systems. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9341bd9390f08574d6052f355a4272b2
https://doi.org/10.1147/jrd.2018.2887388
https://doi.org/10.1147/jrd.2018.2887388
Autor:
Mahdi Hijazi, Michel Kazan
Publikováno v:
AIP Advances, Vol 6, Iss 6, Pp 065024-065024-15 (2016)
We present a predictive Boltzmann model for the cross-plane thermal conductivity in superlattices. The developed model considers particle-like phonons exhibiting wave characteristics at the interfaces and makes the assumption that the phonon heat tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8097636ffdf40d57026e5d974e1aa0
https://doaj.org/article/c3a1efffc4384434b2fcd9b01ceae480
https://doaj.org/article/c3a1efffc4384434b2fcd9b01ceae480
Publikováno v:
The Journal of Chemical Physics
Stochastic thermostats based on the Langevin equation, in which a system is coupled to an external heat bath, are popular methods for temperature control in molecular dynamics simulations due to their ergodicity and their ease of implementation. Trad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7dd4342274adbda5732557d692e3c63